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All Journal Padjadjaran Journal of Dentistry Jurnal Wiyata : Penelitian Sains dan Kesehatan Odonto dental journal Indonesian Journal of Dentistry
Mahardika, Christina
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences Other

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Effect coffee administration on alkaline phosphatase levels during relapse following orthodontic retention in rats: an experimental study Tyas, Septa Yumnaning; Abdurrohman, Muhamat Muhtar S; Mahardika, Christina; Yusuf, Moh
Padjadjaran Journal of Dentistry Vol 36, No 3 (2024): November 2024
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol36no3.57868

Abstract

Introduction: Maintaining teeth in their corrected positions following orthodontic treatment can be extremely challenging. Coffee is one substance whose effects on relapse have been extensively studied. The aim of study is to analyze the effect of coffee administration on relapse after orthodontic retention by evaluating alkaline phosphatase levels. Methods: This experimental laboratory study enrolled SpraqueDawley rats, with brackets applied using Edgewise slot 0.022” system and a nickel-titanium open coil spring fixed between the lower central incisors for 14 days. Based on Federer’s formula, 36 SpraqueDawley rats were randomly divided by simple random sampling into four groups: Group 1 (no retention), Group 2(retention for 3 days), Group 3(retention for 7 days), and Group 4(retention for 2 weeks). The Spraque-Dawley rats in the four experimental groups were given aquadest, 50 mg, and 100 mg/kg coffee intake ad libitum. Orthodontic relapse was assessed by measuring changes in alkaline phosphatase levels between the lower central incisors (the relapse side). Changes in the distance between the central incisors during relapse were observed visually. Alkaline phosphatase levels, which serve as a predictor of recurrence, were determined using an enzyme-linked immunosorbent assay (ELISA). Data analysis was conducted with the Two-way analysis of variance (ANOVA) and a post hoc Tukey test. Results: Overall, we found that a longer retention period was associated with a slower rate of relapse and a shorter overall amount of relapse. In addition, inhibiting osteoclast formation using coffee also reduced orthodontic relapse. Alkaline phosphatase (ALP) and/or its biomarkers could serve as potential therapeutic targets in the prevention and treatment of orthodontic relapse, with changes observed at a value of 0.001. This demonstrates that coffee administration affects alkaline phosphatase levels during relapse after orthodontic retention. Conclusion: Coffee administration increased alkaline phosphatase levels during relapse after orthodontic retention in rats.
ROOT CANAL TREATMENT IN CASE IRREVERSIBLE PULPITIS MAXILLARY PREMOLAR TEETH WITH DIRECT COMPOSITE: CASE REPORT Mahardika, Christina; Melati, Viona Sekar
Indonesian Journal of Dentistry Vol 5, No 2 (2025): August 2025
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/ijd.v5i2.17236

Abstract

Background: Irreversible pulpitis is an inflammatory process in the tooth that involves the pulp. Teeth that experience inflammation in the pulp require root canal treatment to eliminate bacteria. Post root canal treatment teeth with minimal loss of healthy tissue can be restored with direct composite. The purpose of this case report is to convey the success of multiple root canal treatment in cases of irreversible pulpitis with direct restoration. Case: A 47-year-old female patient came to RSGM Unimus, complaining of frequent toothache when eating cold food and in the morning. Intraoral examination showed blackness on the cervical of tooth 14 with positive sondation. Radiographic examination showed radiolucency on the cervical buccal of tooth 14 with pulp depth.Conclusion: The treatment performed showed good results, with root canal treatment in cases of irreversible pulpitis and direct restoration, so that it can maintain teeth, prevent further infection, provide good aesthetics and provide satisfaction to patients.
THE EFFECT SODIUM HYPOCHLORITE 2,5% AND SODIUM THIOSULPHATE AS IRRIGATION ON THE CLEANLINESS OF THE APICAL THIRD ROOT Mahardika, Christina; Kristanti, Yulita; Rinastiti, Margareta
Odonto : Dental Journal Vol 9, No 1 (2022): July 2022
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (324.567 KB) | DOI: 10.30659/odj.9.1.81-87

Abstract

Background: Sodium hypochlorite produces free oxygen and free radicals that cause damage to dentin collagen. Combination with Sodium thiosulfate with the aim of improving root canal hygiene and restoring the oxidizing effect on the dentin surface.The apical third of the root canal is the most difficult part, due to its narrower anatomy, curvature and frequent branching of the root canal. Method: The study used 30 specimens which were divided into 3 groups, group I was irrigated with 2.5% NaOCl, 5% sodium thiosulfate and saline, group II was irrigated with 2.5% NaOCl, 10% sodium thiosulfate and saline and group III was irrigated with 2.5% NaOCl and saline. The tooth length 14 mm measured from apical to crown. The crown down technique was prepared using the M3 Pro gold file. Observation of the level of cleanliness of the root canal was carried out using a Scanning Electron Microscope (SEM) with 5000x magnification at apical third . The results of micrographic photographs are then given a score of 1-4.Result: Irrigated with 5% and 10% sodium thiosulfate showed no significant difference.Conclusion: The differences is not significant, 2,5% irrigation with sodium thiosulfate resulted in a higher cleanliness apical third of the root canalthan 2,5% NaOCl irigation with saline
EFEKTIVITAS EDUKASI KESEHATAN GIGI DAN MULUT TERHADAP PENINGKATAN PENGETAHUAN KADER MUHAMMADIYAH/ AISYIYAH Arinawati, Dian Yosi; Lestari, Rastriana; Lutfia, Almira; Faqih, Kintan; Nissa, Tsalitsa; Mahardika, Christina
Jurnal Wiyata Penelitian Sains dan Kesehatan Vol 12 No 2 (2025)
Publisher : LP2M IIK (Lembaga Penelitian dan Pengabdian Masyarakat Institut Ilmu Kesehatan) Bhakti Wiy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56710/wiyata.v12i2.1077

Abstract

Latar Belakang: Kesehatan gigi dan mulut merupakan bagian integral dari kesehatan umum yang berperan penting dalam kualitas hidup. Rendahnya pengetahuan masyarakat, termasuk kader kesehatan, masih menjadi faktor utama yang berkontribusi terhadap tingginya angka masalah kesehatan gigi di Indonesia. Edukasi kesehatan berbasis komunitas menjadi strategi efektif dalam meningkatkan literasi dan kesadaran masyarakat terhadap pentingnya menjaga kebersihan rongga mulut. Tujuan: Penelitian ini bertujuan untuk mengetahui pengaruh edukasi kesehatan gigi dan mulut terhadap peningkatan pengetahuan kader Muhammadiyah/Aisyiyah di Bantar, Kulon Progo. Metode: Penelitian menggunakan desain one group pretest–posttest dengan pendekatan pre-eksperimental. Sampel terdiri atas 30 kader Muhammadiyah/Aisyiyah yang mengikuti kegiatan edukasi kesehatan gigi dan mulut. Instrumen penelitian berupa kuesioner berisi lima pertanyaan pilihan ganda yang diberikan sebelum dan sesudah edukasi. Data dianalisis menggunakan Paired t-test dengan tingkat signifikansi p < 0,05. Hasil: Terdapat peningkatan skor rata-rata pengetahuan peserta dari 78.79 ± 18.31 pada pretest menjadi 92.12 ± 14.31 pada posttest. Paired t-test menunjukkan adanya perbedaan yang signifikan antara nilai pretest dan posttest (t = 4.74, p < 0,001), menunjukkan bahwa edukasi berpengaruh positif terhadap peningkatan pengetahuan kader. Simpulan: Edukasi kesehatan gigi dan mulut terbukti efektif dalam meningkatkan pengetahuan kader Muhammadiyah/Aisyiyah di Bantar, Kulon Progo. Kegiatan edukasi serupa perlu dilaksanakan secara berkelanjutan untuk mendukung peningkatan perilaku kesehatan masyarakat.
Co-Authors Abdurrohman, Muhamat Muhtar S Dian Yosi Arinawati Faqih, Kintan Lestari, Rastriana Lutfia, Almira Margareta Rinastiti Melati, Viona Sekar Moh Yusuf, Moh Nissa, Tsalitsa Tyas, Septa Yumnaning Yulita Kristanti