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All Journal Padjadjaran Journal of Dentistry Journal of Indonesian Dental Association
Maulina, Shania Tri
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Antimicrobial potency of toothpaste containing gambir (Uncaria gambir) extract Dewi, Siti Rusdiana Puspa; Handayani, Pudji; Anastasia, Danica; Maulina, Shania Tri
Padjadjaran Journal of Dentistry Vol 35, No 2 (2023): July 2023
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol35no2.47130

Abstract

ABSTRACTIntroduction: The biggest problem in oral health is dental caries and periodontal disease. The way to prevent dental and mouth problems is to keep oral hygiene. One of them is adequate plaque control. Plaque control can be done by brushing teeth and using toothpaste. Currently, many herbal ingredients have been used as antibacterials such as gambir (Uncaria gambir). Gambir mainly contains catechins and tannins, which have the ability to inhibit the growth of bacteria. The purpose of this study was to determine the antimicrobial potential of toothpaste containing gambir (Uncaria gambir). Methods: The total sample was 30, and it divided into three groups. Samples were toothpaste containing ten percent of Uncaria gambir extract, fluoride, placebo toothpaste, Streptococcus mutans (Gram-positive), Phorphyromonas gingivalis (Gram-negative), and Candida albicans. Antimicrobial activity of toothpaste with gambir (Uncaria gambir) extract against microorganisms was observed with the formation of inhibitory zone diameter in agar. Data were analyzed by using SPSS with one-way ANOVA and Tukey test. Results: The results showed that toothpaste containing gambir extract could inhibit the Streptococcus mutans (p<0.05), Phorphyromonas gingivalis (p<0.05), Candida albicans (p<0.05) compared significantly with placebo (p<0.05). Antimicrobial toothpaste containing gambir extract had no different effect from toothpaste containing fluoride. However, toothpaste containing gambir extract had significantly different effect than toothpaste containing fluoride. Conclusion: It can be concluded that toothpaste containing gambir (Uncaria gambir) extract has antimicrobial potential against Streptococcus mutans, Phorphyromonas gingivalis, and Candida albicans. These findings showed that the extract of Uncaria gambir possesses potent antimicrobial activity.
Oral Pseudomembrane Kandidiasis in Nasopharynx Cancer - A Case Report Dewi, Siti Rusdiana Puspa; Maulina, Shania Tri
Journal of Indonesian Dental Association Vol 8 No 1 (2025): May
Publisher : Indonesian Dental Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32793/jida.v8i1.1222

Abstract

Introduction. Nasopharyngeal cancer (NPC) is a malignant condition of the nasopharynx. The cancer therapy given is usually radiotherapy (RT), chemotherapy (CT), or a combination of RT and CT. Cancer therapy and poor oral hygiene can lead to susceptibility to fungal infections, one of which is pseudomembranous kandidiasis (thrush). The aim of this report was to present oral pseudomembrane kandidiasis patient with nasopharynx cancer. Case report. A 52-year-old female patient was referred to the hospital's dental clinic with complaints of a white coating on the inside of her cheeks, roof of the mouth, and tongue since ± 1 week ago. The patient feels pain when swallowing and discomfort when opening the mouth. The results of clinical and supporting examinations showed that the patient was diagnosed with oral pseudomembranous kandidiasis. The patient was treated using nystatin drop and chlorhexidine gluconate 0.2% Conclusion. The NPC patient in this case was diagnosed with pseudomembranous kandidiasis (thrush) caused by Candida albicans. Early management of cases of pseudomembranous kandidiasis in NPC patients was very important so that the lesion would not disrupt the general condition of the patient as a whole. Collaboration and coordination from various specialist divisions were needed.
Co-Authors Handayani, Pudji Siti Rusdiana Puspa Dewi