Digital transformation has reshaped how leaders and employees interact, raising both opportunities for flexibility and risks of technostress and digital fatigue. This article synthesizes 25 recent studies (2019-2026) to examine how human-centered leadership relates to employee well-being in digital workplaces. Using a narrative literature review approach, evidence was drawn from journal articles and conference proceedings indexed in Scopus, Web of Science, and Google Scholar, selected through a structured identification, screening, and eligibility process. The synthesis shows that human-centered leadership consistently predicts higher employee well-being across sectors and countries, operating through three mediating pathways: psychological safety and digital trust, work engagement and digital self-efficacy, and technostress mitigation. These relationships are moderated by work arrangement (remote, hybrid, on-site), organizational digital readiness, and industry context. Grounded in the Job Demands-Resources model, Conservation of Resources theory, and Self-Determination Theory, this study proposes an integrated conceptual framework linking human-centered leadership to employee well-being in digitalized settings. The novelty of this article lies in its explicit integration of digital and human-centered leadership literatures, its cross-sectoral synthesis, and its attention to underexplored moderators. Findings offer theoretical propositions for future empirical testing and practical guidance for organizations seeking to humanize digital transformation while safeguarding employee well-being.