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PENGARUH LINAMARIN TERHADAP PENAMPILAN REPRODUKSI INDUK MENCIT (Mus musculus L.) Wahyuni, Fitra; Sumarsono, Sony Heru
Jurnal Ipteks Terapan Vol 11, No 4 (2017): JIT
Publisher : LLDIKTI Wilayah X

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (527.313 KB) | DOI: 10.22216/jit.2017.v11i4.2637

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ABSTRACTThis study was performed to observe the effect of linamarin on reproductive performance, that consist of the number of live fetuses, reabsorption embryo or fetal, fetal death and fetal body weight together with length. Pregnant mice were divided into one control group with administration of distilled water (0 mg/kgb.w/days) and six treatment groups linamarin dose is 0.36; 0.72; 1.26 mg; 2; 4; and 8 mg/kgb.w./days. Linamarin dosing and control begins at 5th to 16th gestation days, at 17-days of gestation caesarean section were performed to pregnant mice to remove foetuses. Statistical analysis used was a variation analysis by ANOVA followed by comparisons between treatments HSD test (Tukey). Giving linamarin observed in the parent mice led to a decrease in average weight gain of the mother during pregnancy compared with controls. In linamarin dose 8 mg/kgb.w/day an increase in embryo reabsorption and fetal death, as well as the observed decrease in fetal body weight and length, but after statistical analysis of the decrease was not significantly different. Linamarin with the doses given in this study is not expected to interfere with pregnancy based on reproductive performance were observed. Keywords: Linamarin, reproductive performance, fetal weight, fetal body length ABSTRAKPenelitian ini dilaksanakan bertujuan untuk mengamati pengaruh linamarin pada penampilan reproduksi yang meliputi jumlah fetus hidup, embrio resorpsi, fetus mati dan berat beserta panjang badan fetus. Induk mencit yang bunting dikelompokkan ke dalam satu kelompok kontrol dengan pemberian akuades (0 mg/kgb.b./hari) dan enam kelompok perlakuan dosis linamarin yaitu 0,36; 0,72; 1,26 mg; 2; 4; dan 8 mg/kgb.b./hari. Pemberian dosis linamarin dan kontrol dimulai pada umur kebuntingan 5 sampai 16 hari, setelah itu pada umur kebuntingan 17 hari mencit dikorbankan nyawanya untuk pengambilan fetus. Analisis statistik yang digunakan adalah analisis variasi dengan ANOVA dan dilanjutkan dengan uji perbandingan antar perlakuan HSD (Tukey). Pemberian linamarin pada induk mencit diamati menyebabkan penurunan rata-rata pertambahan berat badan induk selama kebuntingan dibandingkan dengan kontrol. Pada dosis linamarin 8 mg/kgb.b./hari terjadi peningkatan embrio resorpsi dan fetus yang mati, serta diamati penurunan berat dan panjang badan fetus, namun setelah dilakukan analisis statistik penurunan tersebut tidak berbeda nyata. Linamarin dengan dosis yang diberikan pada penelitian ini diduga tidak mengganggu kebuntingan berdasarkan penampilan reproduksi yang diamati. Kata kunci: Linamarin, penampilan reproduksi, berat badan fetus, panjang badan fetus
STRUKTUR HISTOLOGI DAN JUMLAH SEL GOBLET PADA SEDIAAN HISTOPATOLOGIS RADANG USUS BESAR DENGAN PEWARNAAN HEMATOXYLIN-EOSIN (HE) DAN PERIODIC ACID-SCHIFF (PAS) Chairani Chairani; Fitra Wahyuni; Tofrizal Tofrizal; Salsabila Salsabila
Ensiklopedia of Journal Vol 4, No 3 (2022): Vol 4 No. 3 Edisi 2 April 2022
Publisher : Lembaga Penelitian dan Penerbitan Hasil Penelitian Ensiklopedia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (316.544 KB) | DOI: 10.33559/eoj.v4i3.137

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Abstract: Goblet cells and the mucus they produce serve as an important barrier to prevent pathogens invading the mucosal tissue that can cause inflammation. In the inflamed tissue, will have changed in the structure and number of goblet cells. Hematoxylin-Eosin (HE) staining is a standard stain used to examine the histological structure of tissues while Periodic Acid-Schiff (PAS) is a histological stain other than HE that can stain carbohydrates and carbohydrate-rich macromolecules. The purpose of this study was to observe differences in the structure and number of goblet cells in the inflammatory colon using HE and PAS staining. This study used 27 samples of paraffin block of rat colon tissue which were divided into three groups, namely the normal group, acute intestinal inflammation, and chronic intestinal inflammation. The tissue samples were then stained with HE and PAS staining techniques. In this study, statistical analysis of an independent t-test and Mann-Whitney test was used to observe differences in the number of goblet cells in inflammatory colon tissue using HE and PAS staining in each group. This study concludes that the number of goblet cells that can be observed in inflammatory colon tissue using HE and PAS staining is significantly different with a p-value <0.05 where the average number of goblet cells using PAS staining is higher than using HE.Keywords: goblet cells, inflammatory colon, Hematoxylin-Eosin, Periodic Acid-Schiff.
HUBUNGAN BIOMARKER INFLAMASI C-REAKTIF PROTEIN DENGAN LAJU ENDAP DARAH PADA PASIEN TERKONFIRMASI COVID-19 Renowati Renowati; Waslaini Waslaini; Fitra Wahyuni
Ensiklopedia of Journal Vol 4, No 3 (2022): Vol 4 No. 3 Edisi 2 April 2022
Publisher : Lembaga Penelitian dan Penerbitan Hasil Penelitian Ensiklopedia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (86.326 KB) | DOI: 10.33559/eoj.v1i4.176

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Abstract: China country. It spreads very quickly, namely through physical contact through the nose, mouth, and eyes, and develops in the lungs (C-Reactive Protein). CRP is an acute phase protein synthesized in the liver for non-specific monitoring of local and systemic disease. The erythrocyte sedimentation rate is the rate at which erythrocytes settle in a vertical tube. Research has been carried out to determine the title of the relationship between C-Reactive Protein Levels and Blood Sedimentation Rates in Covid-19 Confirmed Patients. Samples in this study were 60 samples. Then it was found that there were 45 men with a percentage (58.3 %) and a female sex with a percentage of 25 people (41.7 %), and the average c-reactive protein level 477.63 mg/dl and the sedimentation rate was 3.258,33 mm /hour. Then the results of statistical tests obtained results of 0.001 < 0.05. the conclusion is that there is a relationship between levels of c-reactive protein and levels of erythrocyte sedimentation rate in patients suspected of covid-19 with sufficient correlation criteria.Keywords: Corona virus, CRP levels, LED
PENGARUH LAMA WAKTU SIMPAN TERHADAP ANGKA Escherichia coli DALAM AIR MINUM ISI ULANG Fitra Wahyuni; Adi Hartono; Fessy Novita Sari
JURNAL KESEHATAN PERINTIS Vol 5 No 2 (2018): DESEMBER 2018 : Jurnal Kesehatan Perintis (Perintis's Health Journal)
Publisher : LPPM UNIVERSITAS PERINTIS INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (352.178 KB) | DOI: 10.33653/jkp.v5i2.151

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Air merupakan komponen penting bagi tubuh. Menurut Permenkes No.492 Tahun 2010 tentang syarat mikrobiologi air minum adalah tidak ditemukannya bakteri Coliform dan Escherichia coli dalam 100 ml air. Tujuan penelitian ini adalah mengetahui berapa angka Escherichia coli pada air minum isi ulang sebelum dan sesudah disimpan 0 hari, 3 hari dan 6 hari dan mengetahui spesifisitas angka Escherichia coli uji metode CFU berdasarkan uji Indol. Penelitian bersifat survey eksperimen dengan menggunakan uji Kruskal Wallis dengan melakukan observasi dan pemeriksaan bakteriologi sampel air di Laboratorium Mikrobiologi Balai Laboratorium Kesehatan Provinsi Sumatera Barat. Sampel adalah air minum dari masing-masing depot air minum isi ulang di Kelurahan Lubuk Buaya yang dimasukkan ke dalam botol steril. Penelitian ini menggunakan metode filtrasi dengan menggunakan filter steril 0,45 µm. Hasil pemeriksaan laboratorium menunjukkan tiga dari enam sampel mengandung Escherichia coli, sedangkan hasil sensitivitas adalah 100% CFU/ml dan spesifisitas adalah 0% CFU/ml berdasarkan uji Kruskal Wallis yang dilakukan didapatkan hasil p adalah 0,429 ini berarti nilai p>0,05 jadi tidak ada perbedaan angka Escherichia coli yang disimpan 0 hari, 3 hari dan 6 hari. Pengawasan terhadap depot air minum isi ulang di Kelurahan Lubuk Buaya harus lebih ditingkatkan. Petugas kesehatan setempat diharapkan dapat memberikan penyuluhan kepada pemilik atau operator depot agar memperhatikan kebersihan depot serta peralatan yang digunakan.
PERBANDINGAN EFEKTIFITAS ANTIHIPERTENSI DAUN TANAMAN HERBAL MENURUNKAN TEKANAN DARAH PADA TIKUS BETINA INDUKSI HIPERTENSI Fitra Wahyuni; Renowati Renowati; Ummu Habibah; Mona Dewi Utari; Nia Desriva
Ensiklopedia of Journal Vol 4, No 2 (2022): Vol 4 No. 2 Edisi 1 Januari 2022
Publisher : Lembaga Penelitian dan Penerbitan Hasil Penelitian Ensiklopedia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (235.168 KB) | DOI: 10.33559/eoj.v4i2.1011

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The purpose of this study was to compare the effectiveness of leaf decoction of antihypertensive herbs commonly used in Indonesia to lower blood pressure. This study used female rats induced hypertension as animal models. In this experimental study, rats were divided into seven experimental groups consisting of four rats for each group. Rats have induced hypertension with a dose of 2.5 mg/kg BW of prednisone and 2.5% NaCl. Hypertension induction for rats was carried out for 14 days, treatment with herbs of leaf decoction (soursop, starfruit, celery, and salam) with a dose of 200 mg/kg BW for 14 days. Rat's blood pressure was measured by the tail-cuff method at 0 days, 14 days, and 28 days. Statistical analysis used was an analysis of variance with ANOVA followed by a comparison between treatments with Dunnet's test. This study showed that all the herbal plants given were able to reduce systolic and diastolic blood pressure in female rats induced by hypertension, especially boiled celery leaves and star fruit leaves with p-value < 0.05.
Hubungan Intensitas Penggunaan Gadget Terhadap Perkembangan Anak Usia Pra Sekolah Elka Fitri, Dwi; Dwi Sagita, Mutia; Wahyuni, Fitra
Jurnal Pustaka Keperawatan (Pusat Akses kajian Keperawatan) Vol 1 No 2 (2022): Jurnal Pustaka Keperawatan
Publisher : Pustaka Galeri Mandiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55382/jurnalpustakakeperawatan.v1i2.337

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Pemberian gadget yang terlalu dini di era globalisasi menyebabkan dampak negatif terhadap perkembangan anak usia dini. Tujuan penelitian ini untuk mengetahui hubungan intensitas penggunaan gadget terhadap perkembangan anak usia prasekolah di Desa Kubang Jaya Kecamatan Siak Hulu. Desain penelitian adalah penelitian kuantitatif dengan rancangan cross-sectional. Penelitian dilakukan di Desa Kubang Jaya Kecamatan Siak Hulu dengan sampel 148 responden. Alat ukur yang digunakan adalah kuesioner dan Denver II, dengan tujuan menggunakan kuesioner untuk melihat intensitas penggunaan gadget pada anak usia dini. Analisa data terdiri dari analisa univariat dan bivariat dengan uji Chi-square. Hasil penelitian menunjukkan 148 responden Anak Prasekolah yang diteliti di Desa Kubang Jaya Kecamatan Siak Hulu merupakan pengguna gadget dengan intensitas penggunaan gadget yang tinggi sebanyak 53.38%. Perkembangan anak yang normal kategori tinggi sebanyak 62.0% dan yang suspect sebanyak 33,8%. Dari hasil analisis data yang diperoleh hasil nilai p = 0,000 < 0,05. Kesimpulan bahwa terdapat hubungan yang signifikan antara  intensitas  penggunaan  gadget  dengan  perkembangan  pada anak usia prasekolah.
Gambaran Efek Pemberian Vaksin Pfizer Dan Sinovac Di Puskesmas Sidomulyo Kota Pekanbaru Aldo; Ardenny; Isna Ovari; Fitrah Wahyuni
Jurnal Ilmiah Multidisiplin Keilmuan Mandira Cendikia Vol. 1 No. 6 (2023)
Publisher : Yayasan Pendidikan Mandira Cendikia

Show Abstract | Download Original | Original Source | Check in Google Scholar

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Dalam upaya penanggulangan pandemi COVID-19, vaksinasi COVID-19 bertujuan untuk mengurangi transmisi/penularan COVID-19, menurunkan angka kesakitan dan kematian akibat COVID-19, mencapai kekebalan kelompok di masyarakat (herd imunity) dan melindungi masyarakat dari COVID-19 agar tetap produktif secara sosial dan ekonomi. Berdasarkan hasil survey pendahuluan di Puskesmas Sidomulyo terhadap 10 orang yang telah mendapatkan vaksin pfizer dan sinovac didapatkan hasil bahwa 6 orang dengan vaksin pfizer merasakan demam dan nyeri sendi. Kemudian 4 orang dengan vaksin sinovac merasakan nyeri pada bagian yang disuntikkan, demam, nyeri otot. Tujuan penelitian ini adalah untuk mengetahui perbandingan efek pemberian vaksin pfizer dan sinovac di Puskesmas Sidomulyo Kota Pekanbaru. Penelitian ini menggunakan jenis penelitian kuantitatif dengan metode komparatif yaitu jenis penelitian yang diperuntukan mengetahui perbedaan variable yang diteliti. Berdasarkan hasil analisa data memperlihatkan bahwa efek pemberian vaksin pfizer dan sinovac memiliki perbedaan, hal ini dapat dilihat pada penelitian bahwa sebagian besar responden memiliki efek dari pemberian vaksin pfizer dengan kategori sedang yaitu sebanyak 29 responden (64,4%) sedangkan untuk efek dari pemberian vaksin sinovac dengan kategori ringan yaitu sebanyak 24 responden (53,3%)
PMP: Pemberdayaan Kelompok Remaja Masjid Al-Karomah dalam Pembuatan Virgin Coconut Oil wangi Pandanus Amarylifolius (VCO wangi daun pandan) untuk kesehatan kulit lanjut usia di Kecamatan Tenayan Raya Isna Ovari; Desy Winda; Iqra Idri Fikha; Fitra Wahyuni
Journal Of Human And Education (JAHE) Vol. 4 No. 6 (2024): Journal of Human And Education (JAHE)
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jh.v4i6.1849

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The empowerment activities for the Al-Karomah Mosque youth group in Bencah Lesung Village, Tenayan Raya Subdistrict, are a Community Service Program between STIKes Pekanbaru Medical Center and the target partner, the Al-Karomah Mosque youth. The activities include the following sequence: first, the target partner is provided with knowledge about Virgin Coconut Oil (VCO) with the fragrance of Pandanus Amaryllifolius. Next, the mosque youth are trained and guided directly in making Virgin Coconut Oil with the fragrance of Pandanus Amaryllifolius (VCO with pandan leaf fragrance). After that, the VCO is packaged into glass bottles and labeled. Subsequently, the elderly members of the Al-Karomah Mosque congregation (who are members of the Majelis Taklim) are gathered for a health counseling session on the use of VCO with pandan leaf fragrance for elderly skincare. This community service activity has been carried out at the Al-Karomah Mosque. The VCO with pandan leaf fragrance produced from this activity has been well-received by the elderly, as it has numerous benefits for the skin, including the distinctive pandan leaf fragrance, the clarity of the oil, its safety from chemicals, ease of use, the attractive bottle design, and, importantly, its affordability. The outcomes of this activity are as follows: based on data analysis, the Al-Karomah Mosque youth group has increased their knowledge about VCO with pandan leaf fragrance, including its production, packaging, and usage for the elderly. After receiving training and direct practice in making VCO with pandan leaf fragrance, the mosque youth are now able to produce it simply. Evaluation from the elderly who have been using the VCO regularly for 4 weeks indicates noticeable changes in their skin, such as feeling softer, smoother, and more hydrated. The sequence of these activities can be viewed in videos uploaded on Instagram, YouTube, and TikTok by STIKes Pekanbaru Medical Center. The news of this activity has also been featured in the Pekanbaru Pos electronic print media. And will also be published in the Journal of Human and Education (JAHE), which has been accredited by SINTA 5.
Community Service: Training on Creating Dry Herbarium As A Learning Media For Senior High School Students : Pengabdian kepada Masyarakat: Pelatihan Membuat Herbarium Kering Sebagai Media Pembelajaran Untuk Siswa Sekolah Menengah Atas Negeri 11 Kota Jambi Revis Asra*; Ade Adriadi; Dawam Suprayogi; Hasna Ul Maritsa; Fitra Wahyuni
Dinamisia : Jurnal Pengabdian Kepada Masyarakat Vol. 8 No. 6 (2024): Dinamisia: Jurnal Pengabdian Kepada Masyarakat
Publisher : Universitas Lancang Kuning

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31849/dinamisia.v8i6.23755

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This community service program aimed to enhance the competencies of senior high school teachers and students in creating a simple herbarium as an environmentally based biology learning medium. The program employed tutorials and group mentoring, receiving positive feedback from all participants. During the training, five plant species were successfully identified and converted into herbarium specimens, thereby improving practical knowledge and skills. The findings indicate that the use of herbarium effectively deepens students’ understanding of biological concepts through interactive activities both in the classroom and in the laboratory. Additionally, the program fostered the utilization of local biodiversity within the school environment, raising awareness of ecosystem conservation. Overall, the development of a simple herbarium contributed significantly to achieving biology learning objectives in senior high schools and can continue to serve as a sustainable educational resource.
The Utilization of Organic Waste at State Senior High School 3 Muaro Jambi as an Environmentally Friendly Multipurpose Liquid: Pemanfaatan Limbah Organik Di Sma N 3 Muaro Jambi Sebagai Cairan Serbaguna Yang Ramah Lingkungan Mahya Ihsan; Ade Adriadi; Tia Wulandari; Ahmad Sazali; Fitra Wahyuni; Andini Vermita Bestari; Dawam Suprayogi
Dinamisia : Jurnal Pengabdian Kepada Masyarakat Vol. 8 No. 6 (2024): Dinamisia: Jurnal Pengabdian Kepada Masyarakat
Publisher : Universitas Lancang Kuning

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31849/dinamisia.v8i6.24449

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Waste management has become a central issue due to the growing population and the increasing amount of unmanaged waste. This management should be implemented across all aspects of life, from small to large scales. At the smaller scale, waste management is introduced starting from schools, where values are instilled in students that they will carry into adulthood. The habit of managing waste from an early age is expected to become a positive practice in the future. State Senior High School (SMA N) 3 Muaro Jambi is a well-regarded Senior High School in Jambi Province, holding an A accreditation. Currently, SMA N 3 Muaro Jambi does not have an effective waste management system, particularly for organic waste. Additionally, the school is planning to implement the Adiwiyata program, which includes waste management as one of its key points. This community service activity is carried out in three stages: a survey and analysis of the waste problems, socialization of organic waste management into liquid organic fertilizer as an environmentally friendly solution, and practical training in organic waste management. It is hoped that this activity will provide students with knowledge that can lead to business development, serve as a benchmark for other schools in Jambi Province, and help fulfill the requirements for the Adiwiyata program.