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All Journal Jurnal Biologi Tropis
Dhiya Atsila Shofa
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology

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Cutaneous Photobiology in Basal Cell Carcinoma: A Literature Review Husna, Najla Firyal; Baiq Annisa Ulfi Anggraeni; Lalu Maulana Azmi Gifari; Aisya Nur Abida; Dhiya Atsila Shofa; Muhammad Fauzan; Alifa Aswandani; Anang Hermansyah; Komang Puspa Dewi; Muhammad Rezky Audia Aunurrahman; Dyah Purnaning
Jurnal Biologi Tropis Vol. 24 No. 4 (2024): Oktober - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i4.7809

Abstract

Basal cell carcinoma (BCC) is the most common type of skin cancer. BCC arises primarily from prolonged exposure to ultraviolet (UV) radiation, which has been classified as a carcinogenic agent by the International Agency for Research on Cancer (IARC). The prevalence of BCC has increased by approximately 10% annually, which serves as the basis for this article aimed at better understanding the pathophysiology linking UV exposure to BCC and to provide more comprehensive information about BCC. This study uses a literature review approach by collecting data from online databases such as PubMed, ScienceDirect, MDPI and Google Scholar. This literature review comprehensively discusses the definition, etiology, epidemiology, risk factors, pathophysiology, clinical manifestation, treatment, and prevention strategies of BCC. This study find that UV radiation causes genetic mutations, especially in tumor suppressor genes such as PTHC and p53 which lead to development of BCC. In conclusion, early detection through clinical appearance and effective prevention strategies are crucial to significantly enhancing outcomes for patients with BCC.
Co-Authors Aisya Nur Abida Alifa Aswandani Anang Hermansyah Baiq Annisa Ulfi Anggraeni Dyah Purnaning Husna, Najla Firyal Komang Puspa Dewi Lalu Maulana Azmi Gifari Muhammad Fauzan Muhammad Rezky Audia Aunurrahman