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All Journal Promotif: Jurnal Kesehatan Masyarakat ARRUS Journal of Mathematics and Applied Science
Aida Ayu Chandrawati
Universitas Negeri Makassar
Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Mathematics Physics Public Health

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Body Composition Indicators and Cardiovascular Health Score among Young Adults: An Early Cardiovascular Aging Perspective Rayhani Ichsan; Nurul Mufidah Damry; Nurul Mutiah Aminuddin; Aida Ayu Chandrawati; Bhirau Wilaksono; Okto Sofyan
ARRUS Journal of Mathematics and Applied Science Vol. 6 No. 1 (2026)
Publisher : PT ARRUS Intelektual Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35877/mathscience4868

Abstract

This study examined the association between body composition indicators and cardiovascular health score among young adults from an early cardiovascular aging perspective. A cross-sectional analytic study was conducted using de-identified data from 44 young adults, consisting of 35 females and 9 males. Body composition indicators included body mass index, waist circumference, body fat percentage, skeletal muscle percentage, and visceral fat index. Cardiovascular and metabolic markers included systolic blood pressure, diastolic blood pressure, total cholesterol, and random blood glucose. Cardiovascular health was assessed using a modified Life’s Essential 8-based cardiovascular health score. Spearman correlation and age- and sex-adjusted linear regression analyses were performed. Higher adiposity indicators were significantly associated with lower cardiovascular health score, including body mass index, waist circumference, body fat percentage, and visceral fat index. Visceral fat index showed the strongest inverse association with cardiovascular health score. In contrast, skeletal muscle percentage was positively associated with cardiovascular health score. Adiposity indicators were also associated with less favorable blood pressure profiles, particularly systolic blood pressure. These findings suggest that body composition indicators, especially visceral fat index and skeletal muscle percentage, may provide practical insight into early cardiovascular health variation among young adults.
Wound healing activity of Combination Propolis and Coconut Shell Liquid Smoke Ointment on wistar rat second degree Burns wound models Aida ayu chandrawati; Marhaen Hardjo; Syahrijuita Kadir
Promotif : Jurnal Kesehatan Masyarakat Vol. 15 No. 1: JUNE 2025
Publisher : Fakultas Kesehatan Masyarakat, Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/promotif.v15i1.6570

Abstract

Introduction: The delay in burns healing is a serious complication that can lead to disability and death. TGF-?1 contributes significantly to the wound healing process. Chronic wounds that do not heal often indicate a loss of TGF-?1 signaling. Propolis and coconut shell liquid smoke (CS-LS) are natural ingredients that contain antioxidant, anti-inflammatory, and analgesic compounds to accelerate wound healing. This study aimed to prove the effectiveness of using a topical combination of propolis and CS-LS in accelerating the healing process of degree II burns and their relationship with the expression of TGF-?1 in serum. Method: A 14-day in vivo experimental investigation using Wistar rats was carried out with a total sample of 25 rats divided into 4 groups.; Group 1, treated with sulfadiazine ointment; Group 2, treated with propolis ointment; Group 3, treated with CS-LS ointment; Group 4, treated with the combination of propolis and CS-LS ointment, and 1 control group without treatment. Serum TGF-?1 levels were determined by ELISA. Result: Measurements of wound size were on days 0,3,7 and 14. This study obtained results the combination ointment group alone had significantly different TGF-?1 levels from day 7 to day 14 and experienced a decrease in TGF-?1 levels of 52.28 ?/mg. Based on wound size, there was a significant difference in all groups (p<0.05), this was supported by the mean value of wound size which was smaller in the sulfadiazine ointment group and the combination (propolis and liquid smoke) ointment group. Conclusion: The combination of propolis and coconut shell liquid smoke can be considered as an alternative in the treatment of second degree burns because of its ability to reduce TGF-?1 and accelerate burn wound healing. Keywords: wound healing, propolis, coconut shell liquid smoke, TGF-?1
Co-Authors Bhirau Wilaksono Marhaen Hardjo Nurul Mufidah Damry Nurul Mutiah Aminuddin Okto Sofyan Rayhani Ichsan Syahrijuita Kadir