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All Journal International Journal of Health and Pharmaceutical (IJHP) The Journal of Society Medicine (JSOCMED)
Simbolon, Novery
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Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Factors Affecting Lung Function in Patients with Drug-Sensitive Tuberculosis after Treatment. Simbolon, Novery; Pandiaman, Pandia; Andika , Pradana
Journal of Society Medicine Vol. 3 No. 10 (2024): Oktober
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v3i10.171

Abstract

Introduction: Some studies show restrictive and obstruction disorders but still rarely describe factors such as the extent of lung lesions and the history of recurrent tuberculosis to pulmonary physology. To identify the factors affecting the lung function of patients suffering from tuberculosis sensitive to drug post-treatment in patients treated in Outpatient clinic USU Hospital and Adam Malik Hospital. Method: Data that has been collected and then processed and analyzed descriptively to see to see the frequency distribution of the subject of the study based on characteristics. Data in a categorical scale is displayed in percentages while data in a numerical  is shown in ratio values and standard deviations. The data will be processed through bivariate analysis using a chi-sqaure test with a degree of fertility p< 0.05 and be continued by multivariate analyses to find out which factor has the greatest role against the independent variable. Results: Using the enter method, it was found that only one significant independent variable influenced the lung function in patients with drug-sensitive pulmonary tuberculosis in this study is the area of the lesion (p = 0,014) with an Exp (B) value of 4,889 (95% IK = 1,386 – 17,241) which means that subjects with an advanced area of lesion would tend to be at a 4.899 times greater risk of developing an abnormal area of lung function than those with an unadvanced area. Conclusion: The extent of the lung lesion is the variable that most affects the lung function of patients with post-treatment tuberculosis in this study.
Pulmonary Function Recovery After Treatment in Drug Sensitive TB: What Factors Matter? Simbolon, Novery; Pandia, Pandiaman; Pradana, Andika; Anhar, Taufik
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 4 (2025): November 2025
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i4.465

Abstract

Background: Indonesia ranks second globally in tuberculosis burden, and up to 50% of treated patients develop pulmonary dysfunction. Objectives: To identify clinical and radiographic factors influencing spirometric recovery after treatment in drug-sensitive pulmonary tuberculosis. Methods: Analytical observational study with cross-sectional design. Population comprised adults (>18 years) in Medan who completed standard drug-sensitive TB therapy within six months. Sixty participants were selected by consecutive sampling. Instruments included spirometry (Global Lung Function Initiative 2022 equations) and chest radiograph scoring. A structured questionnaire captured demographics, TB history, comorbidities, and smoking. Data analysis involved bivariate tests (chi-square, Kruskal–Wallis, Fisher’s exact) and multivariate logistic regression (enter method). Results: Advanced radiographic lesion extent was the only independent predictor of abnormal spirometry (Exp(B)=4.889; 95% CI 1.386–17.241; p=0.014). Other variables lost significance after adjustment. Conclusion: Initial lesion burden on chest radiograph strongly determines pulmonary function recovery post-treatment. Early stratification by lesion extent is recommended for targeted follow-up and rehabilitation
Co-Authors Andika , Pradana Andika Pradana Anhar, Taufik Pandia, Pandiaman Pandiaman, Pandia