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All Journal Scientia Psychiatrica Sriwijaya Journal of Otorhinolaryngology
Arsan Saliha
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience Public Health

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Climate Change and Mental Health: Exploring the Psychological Impacts of Environmental Distress in Indonesia Najmah Shareeff; Rini Kuswohadi Pramono; Arsan Saliha
Scientia Psychiatrica Vol. 6 No. 2 (2025): Scientia Psychiatrica
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/scipsy.v5i4.179

Abstract

Introduction: Climate change is a global crisis with profound implications for mental health. Indonesia, as a highly vulnerable country, faces escalating environmental challenges that can significantly impact the psychological well-being of its population. This study investigates the psychological impacts of environmental distress related to climate change in Indonesia. Methods: A mixed-methods approach was employed, combining quantitative and qualitative data collection. A cross-sectional survey was conducted with a representative sample of 1,500 Indonesian adults to assess the prevalence of mental health issues associated with climate change concerns and experiences. Qualitative data were gathered through in-depth interviews with 50 individuals from diverse backgrounds who reported experiencing significant environmental distress. Results: Quantitative analysis revealed a strong correlation between climate change concerns and various mental health problems, including anxiety, depression, and post-traumatic stress disorder (PTSD). Individuals directly affected by extreme weather events exhibited higher levels of psychological distress. Qualitative findings highlighted the complex interplay of factors contributing to environmental distress, including fear of future impacts, loss of livelihoods, displacement, and cultural disruption. Conclusion: Climate change poses a significant threat to mental health in Indonesia. The findings underscore the urgent need for comprehensive mental health support services and community-based interventions to address the psychological impacts of environmental distress. Further research is needed to explore the long-term effects of climate change on mental health and develop culturally appropriate coping strategies.
Proteomic Analysis of Saliva in Patients with Oral Squamous Cell Carcinoma: Identifying Diagnostic and Prognostic Biomarkers in Indonesia Rachmat Hidayat; Johan Wirahadi Putro; Arsan Saliha
Sriwijaya Journal of Otorhinolaryngology Vol. 1 No. 2 (2023): Sriwijaya Journal of Otorhinolaryngology
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjorl.v1i1.31

Abstract

Introduction: Oral squamous cell carcinoma (OSCC) is a significant health problem in Indonesia, characterized by high morbidity and mortality rates. Early detection is critical for improving patient outcomes. Saliva, a readily accessible biofluid, holds promise as a non-invasive source for identifying biomarkers for OSCC diagnosis and prognosis. This study aimed to identify salivary proteomic biomarkers associated with OSCC in an Indonesian population. Methods: Saliva samples were collected from 50 OSCC patients and 50 healthy controls. Proteomic analysis was performed using liquid chromatography-mass spectrometry (LC-MS/MS). Differentially expressed proteins were identified and validated using enzyme-linked immunosorbent assays (ELISA). Bioinformatic analysis was conducted to explore the functional roles and pathways associated with identified biomarkers. Results: LC-MS/MS analysis revealed 100 differentially expressed proteins in the saliva of OSCC patients compared to controls. After validation by ELISA, five proteins consistently showed significant differences: Increased levels of S100A7, MUC5B, and IL-6, and decreased levels of Statherin and Histatin 1 were observed in OSCC patients. Conclusion: This study identified a panel of salivary protein biomarkers with potential for OSCC diagnosis and prognosis in the Indonesian population. Further validation in larger cohorts is needed to assess their clinical utility and develop potential screening tools.
Co-Authors Johan Wirahadi Putro Najmah Shareeff Rachmat Hidayat Rini Kuswohadi Pramono