Article Per Year (5 Year)
p-Index From 2021 - 2026
0.444
P-Index
This Author published in this journals
All Journal As-syifaa Jurnal Farmasi Journal of Biotechnology and Natural Science
S. Somadayo, Nur Asma
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
EFEK EKSTRAK DAGING BUAH PALA (Myristica fragrans Houtt.) TERHADAP HISTOPATOLOGI PANKREAS TIKUS PUTIH (Rattus norvegicus) DIABETES Handayani, Sri Windi; S. Somadayo, Nur Asma; Fiskia, Ermalyanti; Nur, Amran
As-Syifaa Jurnal Farmasi Vol 16, No 2 (2024): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v16i2.1202

Abstract

Diabetes mellitus is a severe and persistent illness caused by insufficient production of insulin, a hormone responsible for regulating blood glucose levels, by the pancreas. Diabetes mellitus is a significant public health issue, and its incidence is expected to rise over the next several decades. This study aims to investigate the impact of nutmeg (Myristica fragrans Houtt) pulp extract on the pancreatic histopathology of diabetic white rats (Rattus novergicus). According to research findings, a dose of 100 mg/kgBW of nutmeg pulp extract has been found to effectively lower blood sugar levels without causing harm to the pancreas. On the other hand, doses of 200 mg/kgBW and 300 mg/kgBW of nutmeg pulp extract can drop blood sugar levels, but they have certain side effects. cause harm to the pancreas organ
Antioxidant Capacity and Phytochemical Profile of Jatropha curcas L. Leaf Extracts and Fractions Using the FRAP Method Sadik, Fahmi; Nur, Amran; S. Somadayo, Nur Asma; Hartina, Sitti
Journal of Biotechnology and Natural Science Vol. 5 No. 2 (2025): December
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/jbns.v5i2.14781

Abstract

This study explored the free radical scavenging potential of Jatropha curcas L. leaves, focusing on identifying active biochemical constituents and evaluating antioxidant efficacy through a series of extraction and chemical analysis procedures. Phytochemical screening confirmed the presence of several bioactive secondary metabolites, including alkaloids, saponins, triterpenoids, tannins, and flavonoids. In the Ferric Reducing Antioxidant Power (FRAP) assay, the ethyl-acetate fraction exhibited the highest level of antioxidant activity (9.19 ± 0.38 µmol TE/g), significantly higher than that of the ethanol extract (3.52 ± 0.71 µmol TE/g), as well as the aqueous and n-hexane fractions. This value corresponds to strong activity according to the TEAC classification, indicating that Jatropha curcas leaves are a promising source of natural antioxidants. The total phenolic content (TPC) was determined to be 6.78 ± 0.27% GAE, while the total flavonoid content (TFC) measured 1.35 ± 0.07% QE. These findings indicate that phenolic and flavonoid constituents play a primary role in the antioxidant activity of the extract. Variations significantly influenced the observed outcomes in the extraction methodology and solvent polarity. In summary, Jatropha curcas leaves possess substantial antioxidant potential, particularly within the ethyl-acetate fraction, supporting further development for nutraceutical and pharmaceutical applications.
Co-Authors Amran Nur Ermalyanti Fiskia Handayani, Sri Windi Hartina, Sitti Sadik, Fahmi