Garuda - Garba Rujukan Digital

PEMANFAATAN EKSTRAK ETANOL 70% KULIT JERUK SIAM KINTAMANI (Citrus nobilis L.) SEBAGAI BAHAN AKTIF PADA SEDIAAN LOTION ANTIOKSIDAN Indraswari, Putu Ika Indah; Marangyana, I Gede Bagus Indra
As-Syifaa Jurnal Farmasi Vol 16, No 2 (2024): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v16i2.1239

Kintamani Siam orange (Citrus nobilis L.) is the most dominant orange and has been successfully cultivated in Bali. Kintamani Siam orange peel can be used as a source of natural antioxidants. Antioxidants are substances needed by the body to neutralize free radicals and prevent damage caused by free radicals. This study aims to determine the comparison of antioxidant activity in 70% ethanol extract of Kintamani Siam orange peel through optimization of extraction methods: soxhletation and digestion, then optimizing the lotion formula with 3 comparisons of extract concentrations (2.5%, 5%, 7.5%). The next stage is to compare the physical and chemical properties of the lotion and the antioxidant activity it has. Based on the antioxidant activity test of 70% ethanol extract of Kintamani Siam orange peel, it shows that the extract from the digestion extraction results has antioxidant activity with a strong category. Then the test of the lotion: organoleptic tests, adhesion, spreadability, pH, and viscosity of the lotion preparation, showed that all formulas met all preparation requirements. Meanwhile, for the antioxidant activity test, the results showed that the lotion formula 3 preparation had the highest antioxidant activity with an IC50 of 138.52, which is in the medium category. It can be concluded that the lotion formula 3 preparation is the most optimal formula after the extract is formulated in the form of a antioxidant lotion.

FORMULATION AND EFFICACY TEST OF STICK-HEEL MOISTURIZER MADE FROM 96% ETHANOL EXTRACT OF PAPAYA (Carica papaya L.) LEAVES Marangyana, I Gede Bagus Indra; Listiani, Putu Ayu Ratih
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 10 No 1 (2025)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v10i1.1649

Papaya leaves contain phytochemicals including alkaloids, phenols, flavonoids, tannins, saponins, and steroids, which can function as natural moisturizers to maintain healthy heels. Papaya leaves were extracted using the maceration method with 96% ethanol solvent and evaporated on a rotary evaporator to obtain a thick extract. The yield was 10.2%. It was subsequently combined at concentrations of 5 %, 10 %, and 15% to create a moisturizing heel stick preparation. The physical quality of the stick heel moisturizer preparations was assessed using tests for homogeneity, spreadability, adhesion, pH, organoleptic properties, and moisturizing properties. The mixture produces a brownish-green stick, a semi-solid texture, a distinctive odor of papaya leaves, a pH of 6, good homogeneity, good adherence, and qualified spreadability. The moisturizing test results for FI 5%, FII 10%, and FIII 15% had average values of 2.23%, 1.56%, and 1.15%, respectively. The results of SPSS testing also showed various average values that were significant (p<0.05). From the obtained data, FIII was determined to be the most effective moisturizing formula. Keywords: Papaya leaf, stick heel, moisturizer.

FORMULATION AND EFFICACY TEST OF STICK-HEEL MOISTURIZER MADE FROM 96% ETHANOL EXTRACT OF PAPAYA (Carica papaya L.) LEAVES Marangyana, I Gede Bagus Indra; Listiani, Putu Ayu Ratih
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 10 No 1 (2025)
Publisher : Universitas Muhammadiyah Ahmad Dahlan Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v10i1.1649

Papaya leaves contain phytochemicals including alkaloids, phenols, flavonoids, tannins, saponins, and steroids, which can function as natural moisturizers to maintain healthy heels. Papaya leaves were extracted using the maceration method with 96% ethanol solvent and evaporated on a rotary evaporator to obtain a thick extract. The yield was 10.2%. It was subsequently combined at concentrations of 5 %, 10 %, and 15% to create a moisturizing heel stick preparation. The physical quality of the stick heel moisturizer preparations was assessed using tests for homogeneity, spreadability, adhesion, pH, organoleptic properties, and moisturizing properties. The mixture produces a brownish-green stick, a semi-solid texture, a distinctive odor of papaya leaves, a pH of 6, good homogeneity, good adherence, and qualified spreadability. The moisturizing test results for FI 5%, FII 10%, and FIII 15% had average values of 2.23%, 1.56%, and 1.15%, respectively. The results of SPSS testing also showed various average values that were significant (p<0.05). From the obtained data, FIII was determined to be the most effective moisturizing formula. Keywords: Papaya leaf, stick heel, moisturizer.

HUBUNGAN TINGKAT PENGETAHUAN TENTANG HIPERTENSI DAN CARA MINUM OBAT DENGAN KEPATUHAN TERAPI PADA PASIEN HIPERTENSI Aprianti, Pande Made Ayu; Maharani, Kadek Kartika Putri; Marangyana, I Gede Bagus Indra
JURNAL FARMASI, SAINS, dan KESEHATAN Vol. 5 No. 1 (2025): FARMASAINKES: JURNAL FARMASI, SAINS dan KESEHATAN
Publisher : Fakultas Farmasi Universitas Muslim Nusantara Al Washliyah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32696/farmasainkes.v5i1.5209

Penyakit hipertensi adalah faktor risiko utama penyakit kardiovaskular. Kepatuhan terapi obat dianggap sebagai faktor penting dalam mencegah perburukan kondisi pasien hipertensi. Tingkat pengetahuan mengenai penyakit hipertensi dan cara minum obat diduga berperan penting dalam meningkatkan kepatuhan terhadap pengobatan. Penelitian ini bertujuan untuk mengetahui hubungan antara tingkat pengetahuan tentang hipertensi dan cara minum obat dengan kepatuhan terapi pada pasien hipertensi di Rumah Sakit X Denpasar. Desain penelitian ini adalah observasional analitik dengan pendekatan cross-sectional. Teknik pengambilan sampel menggunakan nonprobability sampling dengan metode purposive sampling. Instrumen penelitian terdiri dari kuesioner pengetahuan hipertensi, kuesioner pengetahuan cara minum obat, dan kuesioner kepatuhan MMAS-8. Analisis data menggunakan uji korelasi Spearman. Hasil penelitian melibatkan 70 responden, menunjukkan bahwa mayoritas responden memiliki tingkat pengetahuan cukup tentang hipertensi (37 responden atau 52,86%) dan pengetahuan baik tentang cara minum obat (60 responden atau 85,71%). Tingkat kepatuhan terapi sebagian besar berada pada kategori sedang (44 responden atau 62,86%). Hasil uji Spearman menunjukkan terdapat hubungan yang signifikan antara pengetahuan tentang hipertensi dengan kepatuhan terapi (p = 0,000; r = 0,483) dan antara pengetahuan tentang cara minum obat dengan kepatuhan terapi (p = 0,002; r = 0,360). Kesimpulan dari penelitian ini adalah terdapat hubungan yang bermakna antara tingkat pengetahuan mengenai hipertensi dan cara minum obat dengan kepatuhan terapi pada pasien hipertensi di Rumah Sakit X.

Overview of Factors Influencing Medication Adherence in Elderly Hypertension Patients Aprianti, Pande Made Ayu; Marangyana, I Gede Bagus Indra; Sudiastini, Ni Ketut Ayu
Jurnal Skala Husada : The Journal of Health Vol 22, No 1 (2025): Jurnal Skala Husada (JSH): The Journal of Health
Publisher : Poltekkes Kemenkes Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33992/jsh:tjoh.v22i1.4177

Hypertension is defined as a sustained increase in blood pressure with a systolic value of ≥140 mmHg and/or a diastolic value of ≥90 mmHg. The risk of developing hypertension increases progressively with age, with a prevalence of more than 60% among individuals over 60 years old (elderly). Treatment success for hypertension depends not only on accurate diagnosis and appropriate therapy but also on patients' adherence to antihypertensive medication. This study aimed to examine the relationship between factors such as knowledge about hypertension and family support with medication adherence among elderly hypertensive patients. Methods: This was an analytical observational study with a cross-sectional design conducted at Hospital X in Denpasar. A total of 70 elderly hypertensive patients participated in the study. Data were collected using the MMAS-8 (Morisky Medication Adherence Scale) to assess medication adherence, and validated questionnaires to measure knowledge of hypertension and family support. Data analysis was performed using the Spearman correlation test. Results: A significant relationship was found between knowledge about hypertension and medication adherence (p=0.000), with a Spearman correlation coefficient of r=0.657, indicating a strong correlation. A significant relationship was also found between family support and medication adherence (p=0.000), with a correlation coefficient of r=0.546, indicating a moderate correlation. Conclusion: Higher levels of knowledge about hypertension and stronger family support are significantly associated with better medication adherence among elderly hypertensive patients. Educational efforts and family involvement are recommended to improve adherence to antihypertensive therapy.

Title

Found 5 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 5 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 5 Documents
Search