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All Journal Berkala Ilmiah Kedokteran Duta Wacana Makara Journal of Health Research
Atmadi, Lenggana Relung
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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THE COVID-19 PANDEMIC: A CASE STUDY OF DISASTER RESPONSE AT UNIVERSITAS KRISTEN DUTA WACANA Atmadi, Lenggana Relung; Vanadian, Heppi; Kushadiwijaya, RM Silvester Haripurnomo
Berkala Ilmiah Kedokteran Duta Wacana Vol. 9 No. 2 (2024): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v9i2.1016

Abstract

Introduction: This study examined the disaster response system of Universitas Kristen Duta Wacana (UKDW) during the COVID-19 pandemic. As a complex institution with interconnected components, UKDW plays a vital role in disaster mitigation and response. Method: Using a qualitative research approach, this study analyzed data from focus group discussions, in-depth interviews, and questionnaires to assess university preparedness and response to the pandemic. Result: The findings revealed that UKDW's response to COVID-19 involved several key stages: pandemic identification, mitigation and preparedness, changes in learning strategies, and evaluation. While the university demonstrated adaptability and resilience, challenges, such as communication gaps and resource limitations, were identified. Conclusion: The study's recommendations include strengthening disaster response training, improving communication channels, and enhancing collaboration with external partners to enhance UKDW's preparedness for future crises.
Current Insight into LDLR and PCSK9 Genetic Variants: Investigating Genetic Keys to Cholesterol in a Cohort of Stroke Patients from Yogyakarta, Indonesia Priskila, Loury; Atmadi, Lenggana Relung; Bagaskara, Arya Taksya; Anggitama, Andreas Mercyan
Makara Journal of Health Research
Publisher : UI Scholars Hub

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Abstract

Background: Stroke is the second leading cause of mortality worldwide. In Yogyakarta, Indonesia, the incidence of stroke (14%) is higher than the national average. We therefore investigated the roles of LDLR rs688 (C/T) and PCSK9 rs562565 (A/G) polymorphisms in familial hypercholesterolemia as predictors of first-time ischemic stroke. Methods: In this case-control study, 119 first-time ischemic stroke patients were divided into dyslipidemia (N = 71) and non-dyslipidemia groups (N = 48). The DNA of the nucleotide polymorphisms LDLR rs688 (C/T) and PCSK9 rs562556 (A/G) was extracted and analyzed using the PCR-RFLP method, and statistical analyses were performed to evaluate their predictive potential. Results: The LDLR rs688 (C/T) CT genotype was the most common in both groups. The TT genotype appeared slightly more frequently in the dyslipidemia group, but no significant association was found with dyslipidemia (p = 0.460). While lipid levels had no significant relationship with LDLR rs688 (C/T), hemoglobin levels differed significantly across the genotypes (p = 0.002), which suggested the biological relevance of hemoglobin. Conclusions: The LDLR rs688 (C/T) polymorphism was not significantly associated with dyslipidemia among the stroke patients. Nonetheless, genotype-related trends related to lipid and hemoglobin levels indicated potential mechanisms that warrant further investigation.
Co-Authors Anggitama, Andreas Mercyan Bagaskara, Arya Taksya Kushadiwijaya, RM Silvester Haripurnomo Priskila, Loury Vanadian, Heppi