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All Journal The International Journal of Medical Science and Health Research The Indonesian Journal of General Medicine
Muhammad Imam, Muhammad Imam
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Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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Prevalence of Depression in Patients With Mild Cognitive Impairment Muhammad Iqbal, Muhammad Iqbal; Muhammad Imam, Muhammad Imam
The Indonesian Journal of General Medicine Vol. 2 No. 6 (2024): The Indonesian Journal of General Medicine
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/zwa5qg67

Abstract

Background: The literature on the prevalence of depression in patients with mild cognitive impairment (MCI) reveals a complex interplay between these conditions that significantly affects patient outcomes. Various studies illustrate how depressive symptoms can exacerbate cognitive decline, increase the risk of progression to dementia, and complicate diagnosis and treatment strategies. Literature Review: The examination of depressive symptoms in patients with MCI, particularly in the context of Parkinson's disease, indicates that these symptoms significantly impair recognition performance. The relationship between social engagement and depression is also critical, as increased social support may mitigate depressive symptoms and improve overall well-being. The challenges in differentiating between MCI and depression are underscored by the overlapping cognitive impairments, suggesting that subsyndromal depressive symptoms may serve as early indicators of dementia. The bidirectional association between depression and cognitive impairment is particularly pronounced in primary care settings, where depression rates among individuals with MCI can reach as high as 32%. Conclusion: In conclusion, the literature collectively highlights the urgent need for integrated approaches in the assessment and management of depression and MCI. Recognizing the interplay between these conditions can lead to improved outcomes through early detection, targeted interventions, and a holistic approach to patient care.
A Comprehensive Literature Review of Vitamin D and Glaucoma Adrian Wijaya, Adrian Wijaya; Yohana, Yohana; Muhammad Imam, Muhammad Imam
The International Journal of Medical Science and Health Research Vol. 5 No. 2 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/6z8qwn30

Abstract

Background: The literature presents a multifaceted examination of the relationship between vitamins, particularly vitamin D, and glaucoma, with a focus on the implications of dietary factors on ocular health. The systematic review and meta-analysis by (Li et al., 2017) establishes a baseline by indicating no significant association between serum vitamin D levels and various types of glaucoma. However, the authors caution against definitive conclusions, emphasizing the need for larger studies to provide a clearer understanding of this relationship. Literature Review: Building on this foundation, (D. Ramdas et al., 2018) expands the investigation to include a broader spectrum of vitamins, revealing a beneficial association between dietary intake of vitamins A and C and open-angle glaucoma (OAG). The review underscores the complexity of the relationship between dietary habits and ocular health, noting that while dietary intake may influence glaucoma risk, blood levels of these vitamins do not consistently correlate with OAG. This complexity is further elucidated by the role of oxidative stress, which is posited as a significant factor in glaucoma pathogenesis. The exploration of neuroprotective properties of vitamins in glaucoma is further detailed by (Adornetto et al., 2020), which highlights the critical role of oxidative stress in the disease's progression. The authors link oxidative stress markers to increased intraocular pressure (IOP), suggesting that antioxidants from dietary sources may mitigate this risk. Conclusion: In conclusion, the literature indicates that while serum vitamin D levels do not appear to have a direct association with glaucoma, there is a potential beneficial role of dietary vitamins, particularly A and C, in influencing the risk and progression of glaucoma through mechanisms related to oxidative stress. The need for further research is emphasized to clarify these relationships and explore the potential of nutritional interventions in glaucoma management.
Effect of Selepressin vs Placebo on Ventilator- and Vasopressor-Free Days in Patients With Septic Shock Muhammad Imam, Muhammad Imam; Sebastian, Sebastian
The International Journal of Medical Science and Health Research Vol. 2 No. 7 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/7036j221

Abstract

Background: The exploration of the effects of selepressin versus placebo in patients experiencing septic shock is an emerging area of interest in critical care medicine. The literature surrounding this topic reveals a complex interplay between vasopressor use, patient outcomes, and potential complications associated with septic shock management. Literature Review: The literature surrounding the effects of selepressin versus placebo in patients with septic shock reveals a nuanced understanding of its potential benefits and limitations in critical care settings. The introduction highlights the significance of vasopressor management in septic shock and sets the stage for a detailed examination of selepressin's role, particularly its impact on ventilator- and vasopressor-free days. Conclusion: In conclusion, the literature suggests that selepressin presents a promising alternative to traditional vasopressors in the management of septic shock, particularly in its ability to maintain hemodynamic stability and potentially reduce the duration of mechanical ventilation. However, the variability in trial outcomes and the lack of significant differences in primary endpoints underscore the need for further research to clarify the role of selepressin in clinical practice. Continued exploration of its effects on secondary outcomes may provide valuable insights into optimizing treatment strategies for patients with septic shock.
Co-Authors Adrian Wijaya, Adrian Wijaya Muhammad Iqbal, Muhammad Iqbal Sebastian, Sebastian Yohana Yohana