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Suprayoga, Imam Mi'raj
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Health Professions Immunology & microbiology Medicine & Pharmacology

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CARDIOPROTECTIVE EFFECT OF REMOTE ISCHEMIC PRECONDITIONING: FROM BENCH TO BEDSIDE Suprayoga, Imam Mi'raj; Anjarwani, Setyasih
Heart Science Journal Vol 5, No 2 (2024): Challenges in the Management of Congenital Heart and Structural Heart Diseases
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub/hsj.2024.005.02.6

Abstract

Remote ischemic preconditioning (rIPC) refers to a cardioprotective phenomenon in which short episodes of ischemia, followed by reperfusion, in one organ or tissue might provide future protection against ischemia/reperfusion damage in other organs, namely the heart. The process involves the activation of humoral, neural, or systemic communication channels, which in turn induce various intracellular signals inside the heart. The primary objective of this review is to provide a concise overview of the potential processes implicated in rIPC cardioprotection, as well as to elucidate current clinical studies aimed at establishing the effectiveness of these techniques in safeguarding the heart from detrimental ischemia/reperfusion injury. In this context, many variables contribute to the attenuation of subcellular processes of rIPC in patients, including advanced age, presence of comorbidities, medication use, and variations in anaesthetic protocols. These factors may account for the observed variability in outcomes across different clinical studies. Additional research, meticulously planned, is needed in order to enhance our comprehension of the pathways and mechanisms associated with both early and late rIPC. A comprehensive understanding of the various routes is crucial in facilitating the translation of medical advancements to the benefit of patients.
Comparison of Clinical Outcomes of Patients With Chronic Vein Insufficiency Underwent Endovenous Laser Ablation With Puncture Above The Knee And Below The Knee Techniques Based on Venous Clinical Severity Score And Venous Disability Score Assessment Suprayoga, Imam Mi'raj; Kurnianingsih, Novi; Sargowo, Djanggan
Heart Science Journal Vol 5, No 3 (2024): The Science and Art of Revascularization in Acute Coronary Syndrome
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub/hsj.2024.005.03.9

Abstract

Background: In chronic venous insufficiency (CVI), a puncture below the knee is done to access the great saphenous vein for endovenous laser ablation (EVLA). Getting a puncture below the knee is difficult in some conditions. Puncture above the knee to access the incompetent saphenous vein is another option. Objective: This study compared CVI patients' clinical results after EVLA with above- and below-the-knee punctures.Methods/Design: This retrospective, single-centre cohort study compared clinical outcomes after two EVLA technical punctures. Puncturing the GSV below the knee was one way. An above-knee GSV puncture was chosen as an alternative. At all follow-up visits, clinical outcomes, closure rate, and complications such as thrombosis, bruising, burn damage, and paresthesia were assessed.  Results: This study has recruited 248 patients, with 132 patients in the below-knee group and 116 patients in the above-knee group. Similar clinical outcomes after the procedure with the Venous Clinical Severity Score (VCSS) were seen in both groups (p = 0.875) and with the Venous Disability Score (VDS) were seen in both groups (p = 0.777) without significant difference. The closure rate in both groups was 100%. Complications, including thrombosis, did not show statistical significance between groups (p = 1.000). Bruising, burn injuries, and paresthesia were absent in both groups.Conclusion: The EVLA for incompetence GSV using an above-knee puncture was safe and effective and should be considered as an alternative method if the below-knee puncture fails.
Unveiling The Diagnosis Pitfall: Complete Heart Block Presenting In Acute Coronary Syndromes Without Chest Pain And Non-Ischemic Electrocardiography In A Young Adult Suprayoga, Imam Mi'raj; Rizal, Ardian; Widito, Sasmojo; Rahimah, Anna Fuji
Heart Science Journal Vol 4, No 4 (2023): The Science and Art of Caring for Critically III Patients in Intensive Cardiac C
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2023.004.04.8

Abstract

Background: The majority of studies indicate that the asymptomatic or atypical presentation of acute coronary syndrome (ACS) as a significant manifestation of coronary artery disease (CAD) is associated with a poor prognosis.Objective: The purpose of this study was to characterize the clinical characteristics and management of ACS patients who presented without chest pain and non-ischemic electrocardiogram (ECG).Case presentation: A 31 years old man with syncope was brought to our hospital. ECG revealed total AV block (TAVB) without ST segment changes. First, he was diagnosed with cardiac syncope because his ECG showed no ischemic sign. He had a strong familial history of CAD, so we examined his cardiac enzymes and found an increase in serial cardiac enzymes. Then, he was diagnosed with non-ST elevation myocardial infarction (NSTEMI). Early invasive strategy with chronic total occlusion (CTO) at osteal right coronary artery (RCA) and acute total occlusion at mid RCA with implantation of 1 DES at osteal-proximal RCA was selected for this patient. After five days of hospitalization, he discharged home with medicines. Conclusion: In order to significantly lower their morbidity and mortality, this group of high-risk patients needs to receive improved early diagnostic and treatment choices.
Successful Emergency Percutaneous Coronary Intervention of Challenging Unprotected Left Main Coronary Artery Disease Patient: How to Prepare and Optimize Suprayoga, Imam Mi'raj; Rohman, Mohammad Saifur; Martini, Heny; Satrijo, Budi
Heart Science Journal Vol 5, No 3 (2024): The Science and Art of Revascularization in Acute Coronary Syndrome
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub/hsj.2024.005.03.11

Abstract

Background: Myocardial infarction (MI) due to unprotected left main coronary artery disease (ULMCAD) is a relatively uncommon presentation. It represents as the anatomical subset of coronary artery disease (CAD) with the highest risk of atherosclerotic obstructive CAD. In the setting of acute MI, the treatment options are limited in this particular condition. Major advances in the field of PCI have made PCI as a viable option for patients with ULMCAD who are equally suited for CABG or PCI.Objective: This study aimed to describe the contemporary evidence PCI for ULMCADCase presentation: A man was admitted to our hospital with crescendo angina accompanied with dyspnea. Electrocardiogram (ECG) showed biphasic t wave on V2-V5 leads. He continued to experience symptoms of ischemia and had increased serial cardiac enzymes. Intra-aortic balloon pump (IABP) support was implemented before performing the PCI. After eight days of hospitalization, he was discharged with stable hemodynamics. Conclusion: PCI has risks and advantages when performed on patients with complex CAD, including ULMCAD. The prognosis for this high-risk patient group can be improved with thorough preparation and effective treatment strategies.
Technical procedure of endovenous laser ablation for chronic venous insufficiency Suprayoga, Imam Mi'raj; Kurnianingsih, Novi
Heart Science Journal Vol. 6 No. 2 (2025): The Complexity in the Management of Heart Rhythm Disorder
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.02.5

Abstract

Venous insufficiency is an often-encountered medical issue. In recent years, a number of procedures have been developed for the treatment of venous insufficiency within the context of minimally invasive surgery. Endovenous laser ablation (EVLA) is a commonly used contemporary method. The ultimate outcome is the formation of fibrotic tissue that seals the lumen of the treated vein. Vein ablation procedures are often performed with local-tumescent anaesthesia, allowing patients to be treated in an office environment and resume full activity immediately afterwards. The use of EVLA is strongly recommended above surgical intervention or foam sclerotherapy, as indicated by a 1A class recommendation. The approach seems to possess significant attributes and benefits in terms of safety and efficacy. This article provides an overview of the technical technique involved in EVLA for the treatment of venous insufficiency. Additionally, it emphasises the significance of EVLA in managing venous insufficiency.
Co-Authors Anjarwani, Setyasih Djanggan Sargowo Kurnianingsih, Novi Martini, Heny Mohammad Saifur Rohman Rahimah, Anna Fuji Rizal, Ardian Satrijo, Budi Widito, Sasmojo