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All Journal PENDIPA Journal of Science Education Walisongo Journal of Chemistry
Sihombing, Chatrina Yohana
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Chemistry Education Mathematics

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Biosynthesis of Silver Microparticles Using Spondias Dulcis Fruit Peel Extract and Its Antibacterial Activity Girsang, Thereshia Margaretta; Purba, Elisabeth; Simamora, Adela Rosalia; Sihombing, Chatrina Yohana; Inabuy, Marchella; Tahya, Candra Yulius
Walisongo Journal of Chemistry Vol. 7 No. 2 (2024): Walisongo Journal of Chemistry
Publisher : Department of Chemistry Faculty of Science and Technology Walisongo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21580/wjc.v7i2.22996

Abstract

In recent decades, the overuse and misuse of antibiotics, along with various social and economic factors, have accelerated the spread of antibiotic-resistant bacteria, including Klebsiella pneumoniae and Pseudomonas aeruginosa, both of which are Gram-negative pathogenic bacteria. Silver particles (AgPs) have garnered significant research interest over the years due to their diverse biological activities, particularly their antibacterial properties. The green synthesis method for silver particles involves synthesizing silver metal particles using natural materials derived from organisms such as plants, resulting in particles that are less harmful to human cells but highly toxic to pathogenic bacteria. Kedondong (Spondias dulcis) is a tropical fruit widely grown in South and Southeast Asia. The peels of this fruit often become organic waste with limited utility. To explore the potential of kedondong fruit peels, this study investigated the synthesis of silver particles using their extract. The ethanolic extract of kedondong fruit peels was analyzed using LC-MS/MS-QTOF, identifying 5 alkaloids, 21 flavonoids, and 17 terpenoid compounds. The total flavonoid and phenolic contents of the extract were determined to be 1.8918 and 12.8104 mg/g of extract, respectively. The silver particles synthesized in this study had an average size of 4641.97 micrometers and a zeta potential of 40.2 mV, as determined by PSA, and were confirmed as silver particles through P-XRD phase analysis. These silver particles exhibited strong antibacterial activity against P. aeruginosa, with an inhibition zone diameter of 19.43 mm, and moderate activity against K. pneumoniae, with an inhibition zone diameter of 11.50 mm, at a suspension concentration of 10 mg/mL. Notably, the P. aeruginosa strain used in this experiment was resistant to the antibiotic amoxicillin.
Identifikasi Miskonsepsi Materi Kinetika Kimia Pada Mahasiswa Tahun Kedua Pendidikan Kimia Teachers College Purba, Friska Juliana; Sihombing, Chatrina Yohana; Inabuy, Marchella
PendIPA Journal of Science Education Vol 9 No 1 (2025): February
Publisher : UNIB Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/pendipa.9.1.46-52

Abstract

The student’s learning outcome on 1st general chemistry is in the low score. Based on the observation, most of the students tend to memorize the formulas rather than understand the concepts that involve in almost chemistry subjects. Sometimes, this could lead to a misconception. Through this research, we are trying to identify the misconception that commonly happen in Chemical Kinetics to avoid the protracted mistakes that might affect the profession of theses student-teacher candidates. From this finding, it will also help the lecturers to find better teaching strategies and methods. The research approach used is a qualitative and descriptive approach. Subject of this research is the seconds year student-teacher candidates of chemistry education in Teachers College. The instrument that help to gather the student’s misconceptions is a four-tier diagnostic questions test, and to get more information on what causing the misconceptions we will do interview to some of the students.  From the analysis there are 52.17% of student who are misconception in rate equation reaction, 30.43% in order reaction, 13.04% inactivation energy, 17.39% rate constant reaction. From the inteview, it was found out that the causes of misconceptions are such as students’ unreadiness, inaccuracy in applying the concept during the learning process and lack of practices.
Biosynthesis of Silver Microparticles Using Spondias Dulcis Fruit Peel Extract and Its Antibacterial Activity Girsang, Thereshia Margaretta; Purba, Elisabeth; Simamora, Adela Rosalia; Sihombing, Chatrina Yohana; Inabuy, Marchella; Tahya, Candra Yulius
Walisongo Journal of Chemistry Vol. 7 No. 2 (2024): Walisongo Journal of Chemistry
Publisher : Department of Chemistry Faculty of Science and Technology UIN Walisongo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21580/wjc.v7i2.22996

Abstract

In recent decades, the overuse and misuse of antibiotics, along with various social and economic factors, have accelerated the spread of antibiotic-resistant bacteria, including Klebsiella pneumoniae and Pseudomonas aeruginosa, both of which are Gram-negative pathogenic bacteria. Silver particles (AgPs) have garnered significant research interest over the years due to their diverse biological activities, particularly their antibacterial properties. The green synthesis method for silver particles involves synthesizing silver metal particles using natural materials derived from organisms such as plants, resulting in particles that are less harmful to human cells but highly toxic to pathogenic bacteria. Kedondong (Spondias dulcis) is a tropical fruit widely grown in South and Southeast Asia. The peels of this fruit often become organic waste with limited utility. To explore the potential of kedondong fruit peels, this study investigated the synthesis of silver particles using their extract. The ethanolic extract of kedondong fruit peels was analyzed using LC-MS/MS-QTOF, identifying 5 alkaloids, 21 flavonoids, and 17 terpenoid compounds. The total flavonoid and phenolic contents of the extract were determined to be 1.8918 and 12.8104 mg/g of extract, respectively. The silver particles synthesized in this study had an average size of 4641.97 micrometers and a zeta potential of 40.2 mV, as determined by PSA, and were confirmed as silver particles through P-XRD phase analysis. These silver particles exhibited strong antibacterial activity against P. aeruginosa, with an inhibition zone diameter of 19.43 mm, and moderate activity against K. pneumoniae, with an inhibition zone diameter of 11.50 mm, at a suspension concentration of 10 mg/mL. Notably, the P. aeruginosa strain used in this experiment was resistant to the antibiotic amoxicillin.
Co-Authors Girsang, Thereshia Margaretta Inabuy, Marchella Purba, Elisabeth Purba, Friska Juliana Simamora, Adela Rosalia Tahya, Candra Yulius