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All Journal JURNAL FARMASIMED (JFM) Jurnal Inovasi Farmasi Indonesia Lumbung Farmasi : Jurnal Ilmu Kefarmasian Jurnal Ilmiah Pharmacy SOCIAL CLINICAL PHARMACY INDONESIA JOURNAL Pharmacy Action Journal Sinteza Jurnal Kabar Masyarakat Karunia: Jurnal Hasil Pengabdian Masyarakat Indonesia Inspirasi: Jurnal Pengabdian Masyarakat IPSSJ
Fajar Amirulah
Fakultas Farmasi, Universitas 17 Agustus 1945 Jakarta
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences Other

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Formulasi Sabun Cair Cuci Tangan dan Uji Aktivitas Bakteri Staphylococcus aureus dari Ekstrak Daun Kelor (Moringa oleifera Lam.) Waris, Dinda Izzatul; Yanti, Silfera Indra; Okzelia, Sari Defi; Amirulah, Fajar
Sinteza Vol. 3 No. 1 (2023): February
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/sinteza.v3i1.7890

Abstract

Soap is what can be used to wash hands so as to avoid bacteria that can cause diseases such as acne and boils. One of the natural ingredients in making soap is Moringa leaves. Moringa leaves are one of the plants that have antibacterial properties, Staphylococcus aureus bacteria are bacteria that can cause infectious diseases such as acne and boils. The purpose of this study was to formulate hand washing liquid soap from Moringa leaf extract (Moringa oliefera Lam.), to evaluate the antibacterial activity of the preparation against Staphylococcus aureus. Moringa extract was obtained by maceration method. Furthermore, phytochemical screening was carried out, then formulated into soap preparations at concentrations of 20% (F1), 25% (F2), and 30% (F3). The preparations were evaluated and tested for activity against Staphylococcus aureus. Based on the results of the study, the yield of ethanol extract of Moringa leaves was 32.35% and contained secondary metabolites such as alkaloids, flavonoids, saponins and tannins. Moringa leaf ethanol extract soap formula met the requirements of all test parameters including pH test, irritation test, specific gravity test, and organoleptic test. The results of the antibacterial activity test gave an inhibition zone of 20.2 mm, 21.5 mm, and 23.2 mm, respectively. For F1, F2 and F3 against Staphylcoccus aureus.
Gambaran Tingkat Pengetahuan dan Perilaku Responden pada Penggunaan Sunscreen di Klinik Kecantikan Wilayah Bekasi Amirulah, Fajar; Yulianti, Yulianti; Yanti, Silfera Indra
Sinteza Vol. 4 No. 1 (2024): February
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/sinteza.v4i1.7926

Abstract

Sunlight contains ultraviolet rays that harm the skin, causing various kinds of skin disorders such as redness, premature aging, black spots, dryness, wrinkles, and skin cancer. Sunscreen is a skin care product that is useful for protecting the skin from the sun. This study aimed to determine the level of knowledge, attitudes, and behavior of female patients at the Beauty Clinic Region of Bekasi about the use of sunscreen. This study uses a descriptive method with a cross-sectional approach. The sample of 92 respondents at the Beauty Clinic Region of Bekasi was selected by purposive sampling by distributing questionnaires. The highest research results were obtained in the age group of 17-25 years as much as 38%, the Senior High School education group as much as 54,3%, the housewives occupation group as much as 35,9%, and private employees as much as 35,9%. The level of sufficient knowledge is 59,8%, sufficient attitude is 56,5% and sufficient behavior is 45,7%. Based on the results of this study, it can be concluded that the respondents at the Beauty Clinic Region of Bekasi have sufficient knowledge and behavior regarding the use of sunscreen.
Efektivitas Penggunaan Obat Antikanker Pada Pasien Kanker Serviks di RSUP Fatmawati Tahun 2024 Amirulah, Fajar; Islamyah, Azmi Annisa; Sari, Dini; Luthfiana, Farisa
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 7, No 1 (2026): Januari
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v7i1.37368

Abstract

Kanker serviks merupakan salah satu penyebab utama kematian akibat kanker pada wanita di Indonesia, yang sebagian besar disebabkan oleh rendahnya cakupan deteksi dini dan keterlambatan diagnosis sehingga efektivitas terapi antikanker menjadi kurang optimal. Penelitian ini bertujuan untuk mengevaluasi efektivitas penggunaan obat antikanker berdasarkan respons klinis pada pasien kanker serviks rawat inap di RSUP Fatmawati tahun 2024. Penelitian ini menggunakan pendekatan observasional dengan desain cross-sectional, menggunakan data dari 156 pasien yang memenuhi kriteria inklusi. Hasil penelitian menunjukkan bahwa kemoterapi kombinasi paklitaksel dan sisplatin merupakan jenis terapi yang paling banyak digunakan. Respons klinis terbanyak adalah respons parsial (56,41%) dan respons lengkap (18,59%), menunjukkan efektivitas terapi berdasarkan dominasi respons klinis positif dibandingkan progresi penyakit. Progresi penyakit terjadi pada 17,95% pasien dan penyakit stabil pada 7,05%. Analisis bivariat menunjukkan bahwa hanya stadium kanker yang memiliki hubungan signifikan terhadap respons klinis (p = 0,017). Penelitian ini menyimpulkan bahwa terapi antikanker yang digunakan cukup efektif, terutama pada pasien dengan stadium awal. Pemilihan terapi yang tepat dan deteksi dini menjadi faktor penting dalam meningkatkan keberhasilan pengobatan kanker serviks
Effectiveness of the Use of Analgetic Drugs in Sectio Caesarea (SC) Patients at RSAL Mintoharjo Atisi; Fajar Amirulah; Rizky Farmasita Budiastuti; Rangki Astiani; Atisi, Atisi
Jurnal FARMASIMED (JFM) Vol 8 No 2 (2026): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/0jfgbm77

Abstract

Cesarean section (CS) is a common obstetric surgical procedure that is frequently associated with moderate to severe postoperative pain, which may delay early mobilization and prolong recovery. This study aimed to evaluate the effectiveness of analgetic use based on the type and number of analgetics on pain intensity and recovery time in post-cesarean section patients at RSAL Mintoharjo. This research was conducted as an observational analytic study with a prospective cohort design involving 80 post-CS patients. Data were collected through medical records, direct observation, and pain assessment using the Numeric Rating Scale (NRS) at 6 hours, 24 hours and on day 2 or 3 postoperatively. Statistical analysis was performed using univariate analysis, Chi-Square test, and one-way ANOVA. The results show that the type of analgesic significantly affects pain intensity at all measurement times (p < 0,05), with combination analgetic regimens providing better pain control that single analgetics. The number of analgetics does not affect pain intensity at 6 hours postoperatively but shows a significant effect at 24 hours and during follow-up interviews. Recovery time is not significantly influenced by the type or number of analgesics, with most patients discharged within three days. Patient age and comorbidities affect pain intensity, while cesarean history and smoking status do not. In conclusion, multimodal analgesia is effective for controlling acute postoperative pain following cesarean section, whereas recovery time is more strongly influenced by patient clinical factors
EVALUASI FUNGSI GINJAL BERDASARKAN FARMAKOKINETIK EKSKRESI PADA PASIEN HIPERTENSI DI INSTALASI RAWAT INAP RSUD CILINCING JAKARTA UTARA Octaviani, Egy; Amirulah, Fajar; Sari, Dini Permata; Astiani, Rangki
SOCIAL CLINICAL PHARMACY INDONESIA JOURNAL Vol 11, No 1 (2026)
Publisher : Universitas 17 Agustus 1945 Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52447/scpij.v11i1.8932

Abstract

Hypertension is a major risk factor for impaired renal function, which may progress to chronic kidney disease (CKD). This study aimed to evaluate renal function based on excretory pharmacokinetic parameters (urea, creatinine, and creatinine clearance) in hypertensive inpatients, and to assess the impact of patient characteristics and types of antihypertensive drugs on renal function decline. This observational analytic study with a cross-sectional design utilized secondary data from 100 medical records of hypertensive inpatients at RSUD Cilincing, North Jakarta, collected during March–April 2025. Most patients were classified in CKD stages 2–3a. The most frequently prescribed therapies were calcium channel blockers (CCBs) and angiotensin receptor blockers (ARBs). Chi-Square analysis revealed significant associations between renal function and gender, age, and CCB use (p < 0.05), while diuretic use was not significantly associated (p = 0.134). These findings highlight the importance of appropriate antihypertensive drug selection and regular renal monitoring to prevent CKD progression in hypertensive patients.
STUDI DRUG UTILIZATION REVIEW (DUR) TERHADAP PENGGUNAAN ANTIBIOTIK PADA INFEKSI SALURAN PERNAPASAN ATAS Amirulah, Fajar
SOCIAL CLINICAL PHARMACY INDONESIA JOURNAL Vol 11, No 1 (2026)
Publisher : Universitas 17 Agustus 1945 Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52447/scpij.v10i2.9411

Abstract

Upper respiratory tract infection (URTI) is a condition characterized by irritation and swelling of the upper respiratory tract without pneumonia, usually accompanied by a cough. According to the Indonesian Ministry of Health, the use of medication can be categorized as rational when the medication given meets the patient's needs. Treatment can only be considered rational if it meets several criteria, namely: the right patient, the right indication, the right drug, the right dose, the right interval of administration, the right duration of administration, and others. The objective of this study is to examine the use of antibiotics for ARI in pediatric patients at Jawilan Health Center. The research method employed is a descriptive method with a cross-sectional design to determine the pattern of antibiotic use for ARI in pediatric patients. Data collection was conducted retrospectively using secondary data obtained from medical records and prescriptions of patients with ARI during the period of May 2024–April 2025 at Puskesmas Jawilan, Serang Regency, Banten. The number of patients was 261 patients aged 1-17 years, diagnosed with ARI and given antibiotics. The most commonly used class of antibiotics was amoxicillin, with 253 administrations (96.9%), followed by cotrimoxazole with 8 administrations (3.1%). The results of the treatment rationality are as follows: correct patient 100%, correct indication 77%, correct drug 100%, correct dosage 86.6%, correct interval of antibiotic administration 100%, and correct duration of antibiotic administration 97.7%. From this research data, it can be concluded that there are still irrational drug administrations below 100% that have long-term effects on the patient's body.
Co-Authors Afifah, Aulia Nur Anton Hadi Wibowo Apriansyah, Hadi Artha Permata Hati Malau Astiani, Rangki Atisi Atisi, Atisi Atmi, Nur Azizah Besin, Cecilia S.M Bulele, Viscaria Kesya Ella Soriarti Nurdin Enjlin Parhusip Farisa Luthfiana Farmasita Budiastuti, Rizky Indah Ananda Putri Islamyah, Azmi Annisa Katamang, Eden Eljire Imanuel Magfirah Magfirah Mahendra, Dimas Akbar Maria Caecilia Novi Yanti Maria Vivian Wea Zi Melani, Inge Tri Meretsha Nurjanah Murida Rusanda Octaviani, Egy Okzelia, Sari Defi Rangki Astiani Rosdayani, Devia Sari, Dini Sari, Dini Permata Suprihanto, Mutiara Thillah S Vrilly Laturake Wardah Amalia Amal Waris, Dinda Izzatul Yanti, Silfera Indra Yulianti Yulianti Zumaero, Zuni