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All Journal Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Idea Pengabdian Masyarakat
Okzelia, Sari Defi
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Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health

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Formulation of Micellar Based Water from Piper crocatum Leaves Extract Using Various Concentrations of Poloxamer 188: Formulasi Micellar Berbasis Air Ekstrak Daun Sirih Merah (Piper crocatum) dengan Variasi Konsentrasi Poloxamer 188 Pratiwi, Hani; Okzelia, Sari Defi; Afiah, Mawar
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 10 No. 2 (2024): (October 2024)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2024.v10.i2.16628

Abstract

Background: Micellar based water (micellar water) is a preparation used to clean the face or makeup with water-based ingredients. Micellar water has moisturizing additives accompanied by antioxidants. Piper crocatum leaves is one of the plants that contain flavonoid compounds so it has the potential as an antioxidant. Micelles are the main component in micellar water preparations derived from amphiphilic block copolymer-type surfactants such as poloxamer. Objectives: The purpose of this study was to formulate, evaluate, and observe the antioxidant activity of the most optimum formulation of micellar based water preparations of Piper crocatum leaves extract with variations in poloxamer 188 concentrations. Material and Methods: The stages of this research were material preparation, extract characteristics evaluation, production of micellar preparations at poloxamer 188 concentrations of 1% (F1); 1.5% (F2); and 2% (F3); preparation characteristics evaluation, stability, particle size, antioxidant activity assay for the optimum formula, and irritation test. Results: The results of the evaluation showed that the pH of the preparation ranged from 4.54 - 4.76; viscosity values ranged from 16.40 - 24.26 cP; particle size ranged from 170.6 – 349.9 nm; and the entire formula did not irritate the skin. Conclusions: Based on the results of this study, it was found that the most optimal concentration of poloxamer 188 was 2% (F3) with IC50 value of 119.63 ppm which categorized as a moderate antioxidant activity.
Edukasi Dapatkan, Gunakan, Simpan dan Buang (DAGUSIBU) Obat pada Masyarakat Secara Home Pharmacy Care Yanti, Silfera Indra; Rohenti, Iin Ruliana; Okzelia, Sari Defi; Shoaliha, Maratun
Idea Pengabdian Masyarakat Vol. 4 No. 02 (2024): May
Publisher : PT.Mantaya Idea Batara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53690/ipm.v4i02.284

Abstract

DAGUSIBU (DApatkan, GUnakan, SImpan, BUang) obat yaitu tatacara pengunaan dan pengelolaan obat secara baik dan benar. Ketidaktahuan masyarakat dalam mengelola obat bisa dipengaruhi oleh pengetahuan, perilaku dan sikap. Kegiatan edukasi bertujuan memberikan pemahaman masyarakat dalam penggunaan obat dan untuk mengetahui tingkat pengetahuan, sikap dan perilaku terkait DAGUSIBU di kecamatan Duren Jaya dan masyarakat sekitar TPS Bantar Gebang Kota Bekasi yang dilakukan secara Home Pharmacy Care pada 55 responden dan pemberian kuesioner untuk mengidentifikasi tingkat pemahaman, perilaku dan sikap masyarakat mengenai DAGUSIBU. Hasil pengabdian tentang pengetahuan, sikap dan perilaku tentang DAGUSIBU adalah baik tetapi masih ada masyarakat yang kurang memahami cara mendapatkan obat, penggunaan antibiotik dan cara pembuangan obat. Dengan kegiatan ini nantinya dapat meningkatkan pengetahuan masyarakat dalam penggunaan obat sehingga perilaku dan sikap masyarakat tentang DAGUSIBU menjadi baik dan benar.
Co-Authors Afiah, Mawar Maratun Shoaliha Pratiwi, Hani Rohenti, Iin Ruliana Yanti, Silfera Indra