Azizah, Fatimah Nur
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Uji Aktivitas Antiinflamasi Ekstrak Etanol Daun Sereh Wangi (Cymbopogon nardus L.) Dengan Metode Denaturasi Protein Sari, Eni Kartika; Dellima, Beta Ria Erika Marita; Azizah, Fatimah Nur
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 6, No 1 (2025): Januari
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v6i1.19785

Abstract

Long-term use of steroid and non-steroidal antiinflammatory drugs (NSAIDs) will cause side effects such as liver damage, digestive disorders and other side effects. Therefore, alternative treatments are needed that utilize the potential of natural ingredients. Lemongrass leaves have active compounds of flavonoids, tannins, steroids, saponins and alkaloids which have the potential to act as antiinflammatory. This study aims to determine the antiinflammatory activity of ethanol extract of citronella leaves using the protein denaturation method. Bovine serum albumin (BSA) as protein for testing. The test was carried out in vitro based on its effect on the inhibition of protein breakdown using BSA as a test medium which was damaged by heating.The results showed that the ethanol extract of citronella leaves has antiinflammatory activity with its ability to inhibit protein breakdown, where the higher the concentration, the higher the % inhibition of inhibition of BSA protein damage. A % inhibition value of more than 20% can be said to have antiinflammatory activity. The IC50 value of the ethanol extract of citronella leaves is 19,608 ppm and diclofenac sodium is 29,124 ppm. The IC50 value of the ethanol extract of citronella leaves and diclofenac sodium is in the very active category because the IC50 value is less than 50 ppm. This indicates that the antiinflammatory activity of the ethanol extract of citronella leaves is higher than diclofenac sodium so that it has the potential to be used as an antiinflammatory agent.
PENERAPAN INTEGRATED MARKETING COMMUNICATION BUMDES SINERGI SIDOWAYAH DALAM PENGELOLAAN DESA WISATA SIDOWAYAH PERIODE 2023 Azizah, Fatimah Nur; Wangi, Maya Sekar; Maserona, Lukas
Solidaritas Vol 8 No 2 (2024): Solidaritas
Publisher : Fakultas Ilmu Sosial dan Ilmu Politik, Universitas Slamet Riyadi Surakarta

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Abstract

Sidowayah Village, located in Klaten Regency, Central Java, has significant potential in the tourism sector, particularly through water attractions like Umbul Siblarak. The Covid-19 pandemic that began in 2020 led to a sharp decline in visitor numbers. Bumdes Sinergi Sidowayah responded to this challenge by implementing an Integrated Marketing Communication (IMC) strategy in 2023 to increase tourist numbers and strengthen the positive image of Umbul Siblarak. This research aims to analyze the effectiveness of IMC implementation by Bumdes in managing Sidowayah Tourism Village. Five key IMC elements, namely advertising, sales promotion, public relations, direct marketing, and personal selling, are examined in depth. The research employs a descriptive qualitative method, with data collected through in-depth interviews, observation, and documentation. The results indicate that IMC implementation successfully increased visitor numbers and reinforced Umbul Siblarak’s image as a safe and attractive tourist destination. Keywords: Integrated Marketing Communication, Bumdes Sinergi Sidowayah, Umbul Siblarak, Marketing, Tourism