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The Effect of Blood Transfusion on Hemoglobin, Hematocrit, and Ferritin Levels in Children with Thalassemia at RSUDZA Banda Aceh Telambanua, Arniat Christiani; Desi Maryasari
International Journal of Midwifery and Health Sciences Vol. 2 No. 3 (2024): IJMHS Vol 2 No 3 (2024)
Publisher : Rajaki of Tulip Medika Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61777/ijmhs.v2i3.89

Abstract

In children with thalassemia, lower hemoglobin levels are associated with several symptoms of general weakness and decreased mental alertness that can cause disturbances in several quality-of-life domains. This study aimed to determine the effect of blood transfusion on hemoglobin levels, hematocrit, and ferritin levels in children with thalassemia at RSUDZA Banda Aceh. This type of research is a Quasy Experiment design one only group pretest and posttest. This research was conducted in July 2024. The population in this study was 59 pediatric patients with thalassemia while sampling used a simple random sampling technique of 30 respondents. Data were analyzed univariately and bivariately using the Paired sample t-test. The results of the study obtained an average hemoglobin level before blood transfusion of 6,350 gr / dL and after 11.44 gr / dL, an average hematocrit level before blood transfusion of 22.50% and after 40.23%, an average ferritin level before blood transfusion of 379.167 µg / L after 35.5475 µg / L. There is an effect of blood transfusion on hemoglobin levels (p = 0.000), hematocrit levels (p = 0.000), and ferritin levels (p = 0.000) in children with thalassemia at RSUDZA Banda Aceh. Based on the results, it can be concluded that blood transfusion affects hemoglobin levels, hematocrit, and ferritin levels in children with thalassemia. Suggestion: It is hoped that all health workers can provide information about the occurrence of thalassemia and it is hoped that they can provide information related to differences in hemoglobin, hematocrit, and ferritin levels in children with thalassemia.
Relationship between Quantitative C-Reactive Protein (CRP) Levels and Leukocyte Counts in Pulmonary Tuberculosis Infection Patients at Arifin Achmad Regional Hospital Telambanua, Arniat Christiani; Ressi Oktaviani; Adewirli Putra
International Journal of Midwifery and Health Sciences Vol. 2 No. 3 (2024): IJMHS Vol 2 No 3 (2024)
Publisher : Rajaki of Tulip Medika Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Pulmonary tuberculosis is a chronic infectious disease caused by Mycobacterium tuberculosis. C-reactive protein (CRP) and leukocyte count are indicators that can reflect the severity of infection in pulmonary TB patients. This study aims to analyze the relationship between quantitative CRP levels and leukocyte counts in pulmonary tuberculosis patients. This study is an observational analytical study with a cross-sectional approach conducted on 30 pulmonary TB patients at Arifin Achmad Hospital, Pekanbaru who met the inclusion and exclusion criteria. Data on CRP levels and leukocyte counts were obtained through laboratory examinations, while demographic data were taken from patient medical records. Normality and linearity tests were performed before correlation analysis using linear regression tests. The average CRP level of patients was 84.14 ± 91.59 mg/L, with the lowest level of 0.71 mg/L and the highest of 316.7 mg/L. The mean number of leukocytes was 10,481 ± 4,625.53 mm³, with the lowest number of 3,190 mm³ and the highest of 21,310 mm³. The results of the bivariate analysis showed no significant relationship between CRP levels and leukocyte counts in pulmonary TB patients (p = 0.378). There was no significant correlation between quantitative CRP levels and leukocyte counts in pulmonary tuberculosis patients at Arifin Achmad Hospital Pekanbaru. Further research with larger samples and longitudinal designs is needed to further explore the relationship between these two variables and their implications in the management of pulmonary TB.
Relationship Between HbA1c Levels and Erythrocyte Sedimentation Rate (ESR) in Type II Diabetes Mellitus Patients at Dr. Rasidin Padang Hospital Demitra Rona; Telambanua, Arniat Christiani
International Journal of Midwifery and Health Sciences Vol. 3 No. 2 (2025): IJMHS Vol 3 No 2 (2025)
Publisher : Rajaki of Tulip Medika Publisher

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Abstract

Type II Diabetes Mellitus is a chronic metabolic disorder characterized by increased blood sugar due to decreased insulin secretion by pancreatic beta cells and/or impaired insulin function. The purpose of this study was to determine the relationship between HbA1c levels and the Erythrocyte Sedimentation Rate (ESR) in Type II Diabetes Mellitus patients at Dr. Rasidin Padang Regional General Hospital. This type of research employs quantitative methods and a descriptive design and was conducted in January 2024. The population was all type II diabetes mellitus patients at Dr. Rasidin Padang Regional General Hospital, totaling 55 patients, while the sampling used the total sampling technique. Data were analyzed univariately and bivariately using the Chi-square test. The results of the study showed that 40% had prediabetes HbA1c levels, and 50.9% had abnormal erythrocyte sedimentation rates (ESR). There was a relationship between HbA1c levels and erythrocyte sedimentation rates (ESR) (p = 0.015) in type II diabetes mellitus patients at Dr. Rasidin Padang Regional General Hospital. Based on the results, it can be concluded that there is a relationship between HbA1c levels and the erythrocyte sedimentation rate (ESR) in type II diabetes mellitus patients at Dr. Rasidin Padang Regional Hospital. Suggestions: All healthcare workers are expected to provide information about the relationship between HbA1c levels and the erythrocyte sedimentation rate (ESR) in patients with type 2 diabetes mellitus. Health workers should conduct HbA1c examinations more routinely in type II diabetes mellitus patients with tuberculosis
Effect Of Red Amber (Amaranthus Tricolor L.) Extract on Soil-Transmitted Helminth Worm Egg Morphology as a Substitute for 2% Eosin Telambanua, Arniat Christiani; Sri Handayani
International Journal of Midwifery and Health Sciences Vol. 3 No. 2 (2025): IJMHS Vol 3 No 2 (2025)
Publisher : Rajaki of Tulip Medika Publisher

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Abstract

The prevalence of worm disease in Indonesia is around 45-65%. The cause of worm infections that are still common in Indonesia is intestinal nematodes. The intestinal nematode group inhabits the digestive tract and is classified within the Soil-Transmitted Helminths group. This group requires contact with warm, moist soil to reach an infectious form. Clinically important soil-transmitted helminth species that infect humans are Ascaris Lumbricoides (roundworm), Trichuris Trichiura (whipworm), Anylostoma Duodenale, and Necator Americanus. This study aimed to determine the effect of red spinach extract (Amaranthus tricolor L.) on the morphology of soil-transmitted helminth eggs as a substitute for 2% Eosin. The research method used was experimental research, and the design used was Statistical Group Comparison. The results of this study are that red spinach extract (Amaranthus tricolor L.) can be used as an alternative coloring in the microscopic examination of soil-transmitted helminth worm eggs. A concentration of 1:1 shows the optimal concentration that can color Soil Transmitted Helminth worm eggs.
Effectiveness Test of Red Spinach Leaf Extract (Amarathus Tricolor L) as a Substitute for Crystal Violet in Gram Staining of Staphylococcus Aureus Bacteria Morphology Diastari Damayanti; Telambanua, Arniat Christiani
International Health Sciences Journal Vol. 3 No. 1 (2025): IHSJ Vol 3 No 1 (2025)
Publisher : Rajaki of Tulip Medika Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61777/ihsj.v3i1.90

Abstract

Gram staining is the most common procedure used to identify bacterial morphology, using crystal violet as the primary dye. However, crystal violet is a synthetic dye that has toxic effects on the environment and health. The purpose of this study was to test the effectiveness of red spinach leaf extract (Amaranthus tricolor L) as an alternative natural dye to replace crystal violet in Gram staining of Staphylococcus aureus bacteria morphology. This type of research is a laboratory experiment with a post-test group control design with samples of Staphylococcus aureus bacterial colonies and red spinach leaf extract with concentrations of 20%, 40%, 60%, 80%, and 100%. Bacterial morphology was observed based on color intensity and clarity of cell shape. The results showed that red spinach leaf extract with a concentration of 100% gave very good morphological results and approached staining using crystal violet. The results of the Kruskal-Wallis test showed a significance value of 0.009 (p <0.05), indicating that there is a significant difference between the concentration groups and the color quality of the Staphylococcus aureus bacteria. This study concludes that red spinach leaf extract is effective as an alternative natural dye to replace crystal violet in Gram staining of Staphylococcus aureus bacteria. Suggestions for further researchers are to conduct further research on the use of natural dyes that can be used as natural dyes to replace crystal violet, which are able to color bacterial morphology in Gram staining.