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All Journal Disease Prevention and Public Health Journal Media Ilmu Kesehatan SOCIAL CLINICAL PHARMACY INDONESIA JOURNAL Journal of Innovation in Community Empowerment (JICE) Journal of Pharmaceutical (JOP)
Hidiyaningtyas, Lutfi
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Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences

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Analisis Efektivitas Biaya (Cost Effectiveness Analysis) Monoterapi Pada Pasien Preeklampsia Di Rsud Sleman Andriani, Yuni; Hidiyaningtyas, Lutfi; Utami, Nendhi Wahyunia
MEDIA ILMU KESEHATAN Vol 12 No 3 (2023): Media Ilmu Kesehatan
Publisher : Universitas Jenderal Achmad Yani Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30989/mik.v12i3.1234

Abstract

Background: Preeclampsia treatment if not treated immediately will cause seizures and even cause death. Rational treatment can be seen from the (outcome) therapy and costs. Pharmacoeconomic analysis can be used to see which drug is most effective in terms of therapeutic outcomes and the costs incurred to obtain that therapy.Objective: This study aims to analyze the cost-effective antihypertensive monotherapy in preeclampsia patients.Methods: The research was conducted at the Sleman Regional Hospital on inpatient preeclampsia patients for the 2021-2022 period. Retrospective data collection in the form of medical record data and financial administration. The effectiveness of therapy is calculated based on blood pressure and length of stay with ICER (Incremental Cost-Effectiveness Ratio) calculations.Results: The description of the characteristics of preeclampsia patients at Sleman Regional Hospital is dominated by those aged 20-35 years, 23 patients (51%), without comorbidities, 39 patients (87%). The most widely used antihypertensive monotherapy was Nifedipine in 33 patients (73%). The cost effective monotherapy is Nifedipine, with an ICER value of Rp. 3,258 based on blood pressure and an ICER of -Rp. 6,041 based on LOSConclusion: Monotherapy that cost effective for hospitalized preeclampsia patients at Sleman Regional Hospital is Nifedipine.
The effect of green bean juice and oxytocin massage on breast milk production in breastfeeding mothers Ayuningtyas, Ika Fitria; Hidiyaningtyas, Lutfi; Ekawati
MEDIA ILMU KESEHATAN Vol 14 No 2 (2025): Media Ilmu Kesehatan
Publisher : Universitas Jenderal Achmad Yani Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30989/mik.v14i2.1509

Abstract

Background: Optimal breast milk production is crucial for a baby's health. Common problems include low milk supply, blocked milk ducts, and anatomical breast issues. These factors include poor breastfeeding technique, stress and fatigue, poor nutrition, and delayed milk production.Objective: To determine the effect of giving green bean juice and oxytocin massage on breast milk production.Methods: The study employed a pretest-posttest design with a control group, divided into two groups: one receiving green bean juice and the other receiving oxytocin massage.Results: The statistical test T-test sig value 0.512 (>0.05), there is no significant difference between giving green bean juice and oxytocin massage on breast milk production. The green bean juice group has a value (3273) higher than the oxytocin massage group (3180), although there is no significant difference, but the giving of green bean juice has a slightly greater effect on breast milk production.Conclusion: Giving green bean juice has a slightly greater effect on breast milk production than giving oxytocin massage. Giving green bean juice and oxytocin massage to postpartum mothers simultaneously increased breast milk production
Relationship Between Potential Antihypertensive Drug Interactions and Target Blood Pressure in Outpatients with Chronic Kidney Disease Hidiyaningtyas, Lutfi; Lestari, Mardiana; Puspitasari, Trinita
Disease Prevention and Public Health Journal Vol. 19 No. 2 (2025): Disease Prevention and Public Health Journal
Publisher : Universitas Ahmad Dahlan

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Background: Chronic kidney disease (CKD) is an increasingly prevalent condition globally and is strongly associated with cardiovascular disease (CVD). Hypertension frequently occurs during the development of kidney disease and is a leading cause of its progression. CKD patients with complications and comorbidities often require combination therapy. However, some drug combinations can cause adverse drug reactions and reduce the efficacy of therapy. One such reaction is failing to achieve the blood pressure target; Method: This research is a non-experimental, analytical study with retrospective sampling. The sample for this study consisted of 71 patients. Potential drug interactions were analyzed using the drug interaction checker application on drug.com. Univariate analysis was performed to describe patient characteristics, and bivariate analysis using the Chi-square statistical test was performed to examine the relationship between the potential interactions of antihypertensive drugs and blood pressure targets; Results: The correlation analysis test results showed no relationship between the potential interaction of antihypertensive drugs and the target blood pressure of CKD patients (p-value = 0.607); Conclusion: There is potential for antihypertensive drug interactions in CKD patients, but they do not statistically affect blood pressure targets.
Application of Oxytocin Massage as an Effort to Create a Healthy and Happy Postpartum Ika Fitria Ayuningtyas; Hidiyaningtyas, Lutfi; Rukmi, Dwi Kartika
The Journal of Innovation in Community Empowerment Vol 7 No 2 (2025): Journal of Innovation in Community Empowerment (JICE)
Publisher : Universitas Jenderal Achmad Yani Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30989/jice.v7i2.1496

Abstract

Awareness of the importance of exclusive breastfeeding has increased among parents. However, several challenges remain, one of which is the inability of mothers to breastfeed until their babies are six months old. This is often attributed to mothers' lack of understanding of proper breastfeeding techniques, including methods to support optimal breast milk production. The purpose of the community service program is to increase breast milk production through oxytocin massage. The method used is divided into three stages: a pretest, providing material on oxytocin massage, followed by an oxytocin massage demonstration, and finally a posttest. The results obtained were 36 respondents, 100% of whom had good knowledge. The posttest results showed a 16.66% increase in knowledge scores compared to the pretest. Husbands/family members were willing to simulate oxytocin massage after being given a demonstration by the midwife. The community service program hopes that husbands/family members will continue to provide oxytocin massage at home for 2-3 minutes every day
Hubungan Potensi Interaksi Obat Antihipertensi terhadap Luaran Klinis Pasien Lansia Waningsih , Ayu; Hidiyaningtyas, Lutfi; Dewi, Novia Ariani
JOURNAL OF PHARMACEUTICAL (JOP) Vol. 3 No. 2 (2025): Journal of Pharmaceutical (JOP)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) UNIVERSITAS JENDERAL ACHMAD YANI YOGYAKARTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30989/jop.v3i2.1673

Abstract

Background: The prevalence of hypertension increases with advancing age. Data from the 2018 Indonesian Basic Health Research (Riskesdas) indicates that hypertension is a common condition among the elderly. Physiological changes, along with alterations in pharmacokinetics, pharmacodynamics, and a higher likelihood of comorbidities, contribute to an increased number of medications consumed by elderly patients. This condition may raise the risk of drug interactions, potentially affecting clinical outcomes. Objective: To determine the association between the potential for antihypertensive drug interactions and clinical outcomes in elderly patients. Methods: This study was an analytical observational study with a retrospective design and purposive sampling technique. A total of 92 patients were included in the study. The research was conducted in the outpatient department of a hospital in Yogyakarta using medical record data from elderly hypertensive outpatients. Drug interactions were analyzed using the drugs.com application, and the association between potential antihypertensive drug interactions and clinical outcomes was analyzed using the chi-square test. Results: Most elderly hypertensive patients were female (65.2%) and had comorbidities or complications (78.3%). The majority of patients received combination therapy (65.2%). Potential drug interactions were identified in 78.3% of patients, with 80.5% classified as moderate in severity and 80.5% involving pharmacodynamic mechanisms. The chi-square test showed a p-value of 0.445, indicating no significant association between the potential for antihypertensive drug interactions and clinical outcomes. Conclusion: There is no significant association between the potential for antihypertensive drug interactions and clinical outcomes in elderly patients
Evaluasi Kesesuaian Terapi Terhadap Pedoman Terapi pada Pasien Rawat Jalan Diabetes Melitus Tipe 2 Dewi, Novia Ariani; Anjani, Windi; Putri, Vera Dian Apsella; Hidiyaningtyas, Lutfi
SOCIAL CLINICAL PHARMACY INDONESIA JOURNAL Vol 11, No 1 (2026)
Publisher : Universitas 17 Agustus 1945 Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52447/scpij.v11i1.9349

Abstract

Diabetes Mellitus (DM) merupakan penyakit metabolik kronis yang ditandai dengan hiperglikemia atau peningkatan kadar glukosa darah yang disebabkan oleh kelainan sekresi insulin, kerja insulin, atau kedua-duanya. Penderita DM rawat jalan di Kabupaten Sleman pada tahun 2022 menduduki peringkat kedua setelah hipertensi yaitu sebesar 5,39%. Salah satu faktor yang mempengaruhi keberhasilan terapi pada pasien DM adalah faktor terapi pasien (jumlah obat, frekuensi minum obat, dan produk obat). Dalam faktor ini, penting untuk menyesuaikan pemberian obat pada pasien dengan pedoman terapi yang digunakan. Penelitian ini bertujuan untuk mengevaluasi kesesuaian terapi yang diresepkan dokter dengan pedoman terapi yaitu PERKENI (2019) pada pasien rawat jalan DM tipe 2 di salah satu rumah sakit pada kabupaten Sleman. Sampel dalam penelitian ini adalah pasien DM tipe 2 rawat jalan pada bulan April – November 2023 yang memenuhi kriteria inklusi diperoleh 99 sampel. Jenis penelitian observasional analitik dengan metode pengambilan data secara retrospektif dengan teknik pengambilan sampel secara consecutive sampling. Hasil evaluasi kesesuaian penggunaan obat 100%, kesesuaian frekuensi penggunaan obat 97,98%, dosis obat 80,81%, jumlah obat 100%, kesesuaian golongan/nama obat 100 %. Pasien DM tipe 2 terbanyak adalah laki-laki, usia 45-59 tahun, komorbiditas pasien tertinggi adalah hipertensi, terdapat kesesuaian dibawah 100% yaitu kesesuaian frekuensi dan dosis obat.
Co-Authors Anjani, Windi Dewi, Novia Ariani ekawati Ika Fitria Ayuningtyas Lestari, Mardiana Puspitasari, Trinita Putri, Vera Dian Apsella Rukmi, Dwi Kartika Utami, Nendhi Wahyunia Waningsih , Ayu Yuni Andriani