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All Journal Jurnal Cakrawala Ilmiah Jurnal Sains Farmasi dan Kesehatan
Oktriyisa Tantia Mini
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Humanities Economics, Econometrics & Finance Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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REVIEW: INOVASI ZAT AKTIF DALAM FORMULASI GRANUL EFFERVESCENT DARI EKSTRAK HERBAL Fatimah Salsabila Algina; Oktriyisa Tantia Mini; Surya Alvina Nazaha; Zulfa Muthi’ah; Mirnawati, Mirnawati; Nor Latifah
Jurnal Cakrawala Ilmiah Vol. 4 No. 3: Nopember 2024
Publisher : Bajang Institute

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Abstract

This study aims to explore the innovative incorporation of active compounds from herbal extracts into effervescent granule formulations. Effervescent granules, known for their rapid dissolution and pleasant taste, have gained significant interest in the pharmaceutical industry. The utilization of herbal extracts as active ingredients in these formulations offers a promising approach to develop novel and natural-based pharmaceutical products. This review will delve into various aspects, including the selection of appropriate herbal extracts, the formulation process, and the evaluation of the physicochemical properties of the resulting granules. Additionally, the challenges and opportunities associated with the development of herbal-based effervescent granules will be discussed. By providing a comprehensive overview of the current state-of-the-art, this review seeks to stimulate further research and development in this exiciting area of pharmaceutical sciences.
Review : Aplikasi Fraksinasi Pada Pemisahan Senyawa-Senyawa Bahan Alam Putri, Peni Oktariyani; Septia Miranti; Mirnawati; Oktriyisa Tantia Mini; Nafach Olya Warasky; Helsy Indarwat; Yolla Rizka Amalia
Jurnal Sains Farmasi Dan Kesehatan Vol. 3 No. 1 (2025): Mei - Agustus
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v3i1.3249

Abstract

Fractionation is an important technique in the separation of secondary metabolites from natural products. This method separates compounds based on differences in polarity, size, or affinity for the stationary phase, resulting in more homogeneous and potentially bioactive fractions. This article reviews various fractionation techniques used to separate compounds from medicinal plant extracts, such as vacuum liquid chromatography (VLC), flash column chromatography, centrifugal chromatography (CLC), and fractionation based on solvents of varying polarity. The studies analyzed demonstrate that appropriate fractionation strategies can produce fractions or isolates with biological activity, including antibacterial, antifungal, antioxidant, and anticancer activities. Therefore, the systematic application of fractionation methods is a crucial step in the development of natural products as drug candidates.
Co-Authors Fatimah Salsabila Algina Helsy Indarwat Jayawarsa, A.A. Ketut Mirnawati Mirnawati Nafach Olya Warasky Nor Latifah Putri, Peni Oktariyani Septia Miranti Surya Alvina Nazaha Yolla Rizka Amalia Zulfa Muthi’ah