Cici Farhana Ambarwanty
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Pengaruh Penundaan Serum Segera dan 24 Jam terhadap Pemeriksaan Kadar Kolesterol di RSU Sinar Kasih Purwokerto Alfiana Herawati; Oksita Asri Widyayanti; Cici Farhana Ambarwanty
Jurnal Medika Nusantara Vol. 3 No. 1 (2025): Jurnal Medika Nusantara
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/medika.v3i1.1631

Abstract

Cholesterol is a component of fat or lipids. Fat is a nutrient that the body actually needs, but if cholesterol levels are high it can cause disease. Cholesterol sufferers in Indonesia are quite high, namely 28% and 7.9% of cases cause cholesterol sufferers in the world to die from this disease. If treated too late, high cholesterol will actually endanger health and can even lead to death. Methods have been developed for examining total cholesterol in the blood in the laboratory, namely enzymatic methods such as Cholesterol Oxidase Deaminase Peroxidase Aminoantipyrine (CHOD-PAP). The aim of this study was to determine the difference in cholesterol levels between immediate serum examination and serum whose examination was postponed. The research was carried out experimentally using a Time Series Design. From the results of the examination of 16 samples, cholesterol levels were obtained based on the Paired Sample T-Test. From the calculation results, namely 0.000, it can be concluded that there is a difference in the results of checking cholesterol levels immediately and with a delay of 24 hours.
Hubungan Kadar HbA1c Dengan Kadar Serum Kreatinin Pada Penderita Diabetes Melitus Tipe 2 Di RSU Sinar Kasih Purwokerto Oksita Asri Widyayanti; Malta Bethlysa; Cici Farhana Ambarwanty
Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran Vol. 2 No. 3 (2024): Juli : Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/termometer.v2i3.4049

Abstract

Diabetes Mellitus is a metabolic disorder caused by a decrease in insulin products in the body. The World Health Organization estimates an increase in the number of diabetes mellitus sufferers from 8.4 million in 2000 to around 21.3 million in 2030. Chronic diabetes mellitus sufferers can cause complications, one of which is kidney complications. Kidney damage can occur due to uncontrolled blood sugar levels. Complications of diabetes mellitus can be detected by examining HbA1c. HbA1c is a non-enzymatic binding of glucose molecules to hemoglobin through a post-translational glycation process. Uncontrolled HbA1c levels can cause various complications in the body.The samples used for this research were 106 samples with normal HbA1C examination results, namely 59 patients and high results, namely 47 patients. Creatinine examination with normal results was 81 patients and high results were 25 patients. The P-value from the calculation results is 0.066 higher than 0.005. Based on the results of the chi square calculation, it can be concluded that there is not a relationship between HbA1C examination and creatinine examination in type 2 diabetes mellitus patients at Sinar Kasih Hospital.