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All Journal Majalah Kedokteran Nusantara The Journal Of Medical School Jurnal Impresi Indonesia The Journal of Society Medicine (JSOCMED) MEDALION JOURNAL: Medical Research, Nursing, Health and Midwife Participation
Iqbal, Kiki Mohammad
Fakultas Kedokteran USU
Religion Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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Neuropsychiatric systemic lupus erythematosus Kiki Mohammad Iqbal
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 45, No 2 (2012): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Abstract

Systemic lupus erythematosus (SLE) is a chronic, heterogenous, autoimmun disease with diverse clinical manifestations, which can include end-organ damage. Neuropsychiatric systemic lupus erythematosus (NP-SLE) is defined as abnormalities of the central, peripheral and autonomic nervous systems and the psychiatric syndromes observed in patients with SLE for which other causes have been excluded.. However, the pathogenic mechanisms that result in primary neuropsychiatric manifestations in NP-SLE are throught to include autoantibodies, vascular abnormalities, and the local production of inflammatory mediators. Diagnosis is typically achieved throught careful analysis of clinical, laboatory, and imaging data on a case-by-case basis. A better approach to management of NP-SLE may be achieved by : 1) the recognition of the antiphospholipid syndrome and its treatment with anticoagulants; 2) the use of steroids, especially in patients with mild manifestations; and 3) the use of pulse cyclophosphamide in diffuse / nonthrombotic CNS lupus.Keywords : neuropsychiatric; systemic lupus erythematosus
CORRELATION OF BODY MASS INDEX, AGE AND GENDER WITH THE DEGREE OF SPONDYLOLISTHESIS ON LUMBOSACRAL XRAY PHOTOS AT HAJI ADAM MALIK HOSPITAL MEDAN Dina Utami Lubis; Evo Elidar Harahap; Kiki Mohammad Iqbal
MEDALION JOURNAL: Medical Research, Nursing, Health and Midwife Participation Vol. 5 No. 3 (2024): September
Publisher : PT. Radja Intercontinental Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59733/medalion.v5i3.124

Abstract

Introduction :Spondylolisthesis is a displacement of one vertebra relative to the vertebra below it with an estimated prevalence of spondylolisthesis of 6 to 7% at age 19 years, and up to 18% of adult patients undergoing MRI of the lumbar spine. Grade I spondylolisthesis accounts for 75% of all cases. Various factors can influence the occurrence of spondylolisthesis such as BMI, age and gender. Objective. This study aims to determine the characteristics and analysis of the relationship between spondylolisthesis patients and lumbosacral x-rays based on body mass index, age and gender as well as the local anatomical distribution and frequency of spondylolisthesis degrees. Results :A total of 120 patients were predominantly aged>60 years old, female and obese. Based on the location of spondylolisthesis, most of them are at L4-5. There are almost the same numbers of scoliosis patients and those without scoliosis. The majority of spondylolisthesis patients are dominated by spondylosis on lumbosacral xray examination. There was a relationship between spondylolisthesis and age, BMI and gender (p<0.05). Spondylolisthesis patients with female risk factors are at risk of experiencing spondylolisthesis (OR=6.490) and obese patients are at risk of experiencing spondylolisthesis (OR=4.024). Discussion:The prevalence of spondylolisthesis and patient gender may be related to the influence of the female sex hormone estrogen on tissues associated with the human musculoskeletal system. An increase in body mass index (BMI), an axial load on the intervertebral discs and facet joints, causes an increase in compressive forces on the spine. Age has the potential to be a determining factor in degenerative conditions with the occurrence of disc narrowing, osteoarthritis (OA) of facet joints, and degenerative spondylolisthesis showing a significant linear trend. Conclusion :There is a significant relationship between spondylolisthesis and BMI, age and gender in spondylolisthesis patients who underwent lumbosacral xray examination at H Adam Malik Hospital Meda. The variables gender and BMI are the most significant risk factors. Spondylolisthesis patients with female risk factors are at risk of experiencing spondylolisthesis 6.5 times greater and patients who have an obese BMI are at risk of experiencing spondylolisthesis 4 times greater than patients without this condition at RSUP H Adam Malik Medan.
Relationship between Cluster of Differentiation 4 Levels and Neuroopthalmic Manifestations in HIV Patients in Haji Adam Malik General Hospital Medan Sinaga, Sofi Oktaviera; Ritarwan, Kiking; Iqbal, Kiki Mohammad
Journal of Society Medicine Vol. 2 No. 11 (2023): November
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v2i11.95

Abstract

Introduction: The neuroophthalmic manifestations of HIV infection involve afferent and efferent visual pathways. Neuroophthalmic involvement is caused by direct infection and opportunistic infections. Screening for neuroophthalmic manifestations should be done even without vision complaints to identify neuroophthalmic signs and symptoms and refer to a neuroophthalmologist soon. The aim of this study was to determine the relationship between CD4 levels and neuroophthalmic manifestations in HIV positive patients Method: It was a cross-sectional study with primary data sources taken consecutively from HIV positive patients at Haji Adam Malik General Hospital in Medan. Subjects were examined for CD4 levels and also performed the neuroophthalmic and neurological physical examination such as visual acuity examination, visual field, pupil examination and funduscopy. Results: There were 45 subjects with demographic characteristics the most of subjects were male (71.1%), age group 31-40 years (55.6%) with an average age of 35.98 + 9.23 years, self-employed (46.7%), married (60% ) and Bataknese (62.8%). CD4 levels < 200 cells/µL were found at 55.6% with a median value of 162 cells/µL (30-878). The most of neuroophthalmic clinical manifestations were found in 52% of subjects with CD4 levels <200 cells/µL with symptoms of blurred vision (22.2%) and clinical signs of abnormalities on fundoscopy (20%). There was a significant relationship between CD4 levels and neuroophthalmic manifestations in HIV patients (p<0.005). Conclusion: There was a significant relationship between CD4 levels and neuroophthalmic manifestations in HIV patients (p<0.005).
Correlation between National Institute Health Stroke Scale and QT Dispersion In Acute Ischemic Stroke Siahaan, Widya Prawirani; Arina, Cut Aria; Iqbal, Kiki Mohammad
Journal of Society Medicine Vol. 3 No. 1 (2024): January
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v3i1.120

Abstract

Introduction: Stroke is a global health problemwhose incidence is increasing every year throughout the world. Stroke can cause disorders of the autonomic system in sufferers including cardiovascular disorders. Several studies examining cardiovascular disorders after acute stroke using electrocardiography (ECG), one of which is the QT Dispersion. The aim of this study was to examine the relationship between the National Institute of Health Stroke Scale and the QT Dispersion. Method: This research is analytic correlation with cross-sectional design. The study sample consisted of 50 acute ischemic stroke patients. QT Dispersion were assessed based on the results of the ECG examination on the first day of treatment. Stroke outcome assessment using the NIHSS score was assessed on the first day of treatment. Results: The mean age of the 50 subjects is 57,28±12,216. The majority were male (64%), the majority were Batak (72%), 58% Subjects graduated fromsenior high school and the majority works as housewives 32%. The mean NIHSS value obtained was 8,74±6,599.81 and the mean QTd value was 142,40±73,250 ms. The most common infarct site in this study were basal ganglia (21%). There was a significant correlation between NIHSS scores and QTd in acute ischemic stroke patients (r= 0,668, p<0.05). Conclusion: There was a significant relationship between NIHSS scores and QT dispersion in acute ischemic stroke patients (p<0.05).
Hubungan Antara Kadar Serum Laktat dengan Karnofsky Perfomance Status, Derajat Keganasan dan Ukuran Tumor pada Pasien Tumor Primer Intrakranial di RS Adam Malik Medan Khairina, Fadilah Oliv; Nasution, Irina Kemala; Iqbal, Kiki Mohammad
Jurnal Impresi Indonesia Vol. 5 No. 2 (2026): Jurnal Impresi Indonesia
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jii.v5i2.7562

Abstract

Laktat berperan sebagai produk metabolik utama dari glikolisis anaerob pada sel tumor otak yang mengalami efek Warburg. Peningkatan kadar laktat mencerminkan aktivitas metabolik, hipoksia jaringan, dan agresivitas tumor, serta berpotensi sebagai biomarker prognosis keganasan tumor primer intrakranial. Mengetahui hubungan antara kadar serum laktat dengan dengan skala Karnofsky Perfomance Status (KPS), derajat keganasan dan ukuran tumor pada pasien tumor primer intrakranial. Penelitian ini menggunakan desain cross sectional pada 32 pasien tumor primer intrakranial di RS Adam Malik Medan yang memenuhi kriteria inklusi dan eksklusi dilakukan pengambilan data identitas, penilaian status fungsional pasien dengan Karnofsky Perfomance Status (KPS), derajat keganasan tumor berdasarkan hasil histopatologi dan ukuran tumor berdasarkan hasil pencitraan radiologi. Dari 32 subjek penelitian, didapatkan mayoritas pasien dengan derajat keganasan tumor rendah/low-grade (71,9%), nilai median ukuran tumor 40,81 cm3 (2,41 - 353,56 cm3), KPS 70 (40-90), kadar laktat serum 2,4 mmol/L (1,41 - 6,66 mmol/L). Berdasarkan uji korelasi Spearman, terdapat hubungan yang signifikan antara kadar laktat terhadap derajat keganasan tumor dengan kekuatan korelasi kuat (r = 0,772, p < 0,001). Namun, tidak dijumpainya hubungan yang bermakna antara kadar laktat dengan skala KPS dan ukuran tumor pada pasien tumor primer intrakranial dengan nilai p = 0,195 dan p = 0,903 berurutan.  Kadar laktat serum berkorelasi positif dengan derajat keganasan tumor primer intrakranial.
Co-Authors Cut Aria Arina Dina Utami Lubis Evo Elidar Harahap Khairina, Fadilah Oliv Kiking Ritarwan Nasution, Irina Kemala Siahaan, Widya Prawirani Sinaga, Sofi Oktaviera