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Combining antimicrobial photodynamic therapy with curcumin and with methylene blue against S. mutans Hariyani, Ninuk; Setyowati, Dini; Armadanty, Talsha Irzaputri; Amiati, Devy Ratriana; Dani, Anugrah Putra; Shoaib, Lily Azura; Shanbhag, Namita
Majalah Kedokteran Gigi Indonesia Vol 10, No 2 (2024): August
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.94888

Abstract

ntimicrobial photodynamic treatment (aPDT) is a treatment method that links a light source to a photosensitizing carrier. There is no clear standardization regarding the exact therapeutic concentration when it is combined with curcumin or methylene blue, and there is no comparison of their activities toward S. mutans. We aimed to assess the best composition of the combination of aPDT and curcumin and with the combination of aPDT and methylene blue in reducing the number of S. mutans biofilms. The searches were carried out in Pubmed, ScienceDirect, and Proquest from 2015 to April 2023; collecting in-vitro and in-vivo research. Two authors independently reviewed studies, assessed their quality and eligibility, then extracted the data. 14 articles that met the inclusion criteria were retained. The final results were then grouped into 2, showing the effectiveness for a combination of aPDT and methylene blue and of aPDT and cucumin (9 and 5 articles, respectively). Each combination has different aPDT properties. The combination of aPDT and methylene blue is effective in reducing S. mutant biofilm in 660 nm diode laser wavelength and 40 mW output power. Furthermore, aPDT combined with curcumin is effective in reducing S. mutants biofilm in a wavelength of 405 nm and an irradiation time of 50-150 seconds. The addition of EDTA in a combination of aPDT and curcumin could increase its effectivity.
Penyuluhan Bahaya Bakteri Plak pada Fase Geligi Pergantian di MI Plus Darussaadah Lirboyo Kota Kediri Ratriana Amiati, Devy; Khafid , Mohammad; Kusumastuti , Endah
Journal of Science and Social Development Vol. 8 No. 1 (2025): Journal of Science and Social Development
Publisher : Universitas Nahdlatul Ulama Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55732/jssd.v8i1.1661

Abstract

Abstract. Problem: Dental caries is a disease caused by plaque bacteria. Dental caries often occurs in children aged 6-12 years in the changing teeth phase. Changing teeth are easily damaged by plaque bacteria because at this phase the tooth structure has not matured. Efforts that can be made to avoid dental caries are to provide counseling about the dangers of plaque bacteria in the changing teeth phase. Method: The method used is counseling with an open-ended process-based approach using PowerPoint Presentation (PPT) media and leaflets. The type of data obtained is primary data (pretest and posttest). Results: The results of the counseling obtained an average knowledge before counseling of 54.44% and after counseling of 88.04%.