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Systematic Review of Green Seaweed Caulerpa racemosa as an Anti-Inflammatory Agent: Current Insights and Future Perspectives Prayogo, Ega Widya; Irawati Sholikhah; Suciati; Dej-adisai, Sukanya; Retno Widyowati
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 11 No. 2 (2024): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v11i22024.156-173

Abstract

Background: Seaweed is a marine biota with many benefits, one of which is C. racemosa. It is one type of seaweed that is quite widely found in Indonesia. Objective This study investigated the anti-inflammatory activity of C. racemosa using various in vitro and in vivo approaches. Methods: A literature review was conducted by searching for research data on C. racemosa. The literature was obtained from PUBMED, ScienceDirect, Scopus, SpringerLink, and Google Scholar using the keywords C. racemosa, sea grapes, in vivo, in vitro, and anti-inflammatory. The search identified 1313 articles with 100 articles in Scopus, 100 articles in ScienceDirect, 0 articles in PubMed, 3 articles in SpringerLink, and 1,110 articles in Google Scholar. Results: The study showed 12 articles found C. racemosa has the ability as an anti-inflammatory both with in vitro and in vivo study approaches and supported by data on proximate composition which is quite high and substance consisting of various bioactive constituents including flavonoids, phenolics, phytosterols, terpenoids, saponins and alkaloids where the anti-inflammatory active isolate caulerpin was successfully isolated. C. racemosa is able to reduce the inflammatory response by inhibiting NO production and the release of cytokines and inflammatory mediators such as AMPK, mTOR, TNF-α and IL4. Conclusion: C. racemosa indicated that this species is a rich source of phytochemicals with many pharmacological activities, one of which is anti-inflammatory. Further research is required to explore the relationship between secondary metabolites and their activities.
Sosialisasi dan pelatihan inovasi produk berbahan dasar jahe dan sereh sebagai aset ekonomi desa Pulungdowo Ekasari, Wiwied; Suciati, Suciati; Iswajuni, Iswajuni; Lahardo, Devanus; Prayogo, Ega Widya; Nirmala, Afrida Yunda; Minnah, Fakhrina Fauzul; Imelda, Viola Puspa; Idayati, Dihan Isro; Putri, Lailatul Pratama; Putri, Nindya Tresiana
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 8, No 1 (2024): March
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v8i1.22208

Abstract

AbstrakDesa Pulungdowo yang terletak di Kecamatan Tumpang, Kabupaten Malang, Jawa Timur memiliki sumber daya alam melimpah yakni jahe dan sereh, yang berpotensi dijadikan produk olahan inovatif dan dapat menjadi komoditas unggulan di Desa Pulungdowo, namun sampai saat ini pemanfaatannya belum maksimal karena kurangnya pengetahuan masyarakat dalam pengolahan serta pemasaran produknya di pasaran. Fokus utama program pengabdian adalah memberikan penyuluhan serta pelatihan baik secara teori ataupun aplikasi dalam pengembangan produk olahan berbasis jahe dan sereh, serta pemanfaatan teknologi guna memasarkan produk secara luas serta bernilai jual. Tujuan khusus yang diharapkan tercapai lewat program pengabdian masyarakat ini adalah produk olahan berbasis jahe dan sereh sebagai industri kreatif yang dapat meningkatkan perekonomian Desa Pulungdowo. Adapun materi penyuluhan diberikan dengan metode ceramah mengenai pemanfaatan tanaman jahe, sereh, dan tanaman sekitar untuk kesehatan serta pembuatan produk olahannya; dan teknik pemasaran produk yang baik. Dilanjutkan dengan pelatihan pembuatan produk yakni sirup JARECANG, permen agar JARECANG, dan stik daun kelor melalui pendampingan fasilitator. Berdasarkan hasil pre-test dan post-test yang dianalisis secara kuantitatif diperoleh nilai rata-rata sebesar 57,67 dan 72,67; yang menunjukkan adanya peningkatan pengetahuan mitra terhadap materi penyuluhan yang diberikan. Kata kunci: desa pulungdowo; jahe; sereh; kelor. AbstractPulungdowo Village, which is located in Tumpang District, Malang Regency, East Java, had abundant natural resources such as ginger and lemongrass, which had the potential to be developed into innovative processed products and become superior commodities in Pulungdowo Village. However, their utilization was not yet optimal due to the lack of knowledge among the community in processing and marketing of the products in the market. The main focus of the community service program was to provide education and training, both in theory and application, in the development of ginger and lemongrass-based processed products, as well as the use of technology to market the products widely and of high value. The specific goal that was expected to be achieved through this community service program was the development of ginger and lemongrass-based processed products as a creative industry that could improve the economy of Pulungdowo Village. The education materials were provided through lectures on the use of ginger, lemongrass, and other plants for health and the making of processed products, as well as techniques for marketing the products effectively. This was followed by training on the making of JARECANG syrup, JARECANG agar candy, and moringa leaf sticks through facilitator guidance. Based on the results of pre-tests and post-tests analyzed, an average score of 57.67 and 72.67 was obtained, respectively, indicating an increase in participants’ knowledge. Keywords: pulungdowo village; ginger; lemongrass; moringa.