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The Analysis Study of Effectiveness of Vitamin D Supplementation for Prevention of Open Angle Glaucoma: A Comprehensive Systematic Review Cintya Ristimawarni; Kaharuddin; Nazza Rizky Ramdhagama
The International Journal of Medical Science and Health Research Vol. 8 No. 1 (2025): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/z22gdr33

Abstract

Background: Over 70 million people worldwide suffer from glaucoma. Over the next 20 years, this is anticipated to rise to 111 million. Primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG) are the two principal subtypes of glaucoma. The most prevalent glaucoma subtype is POAG. The aim: The aim of this study to show about effectiveness of vitamin D supplementation for prevention of open angle glaucoma. Methods: By the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. This search approach, publications that came out between 2014 and 2024 were taken into account. Several different online reference sources, like Pubmed, SagePub, and Sciencedirect were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done. Result: Seven publications were found to be directly related to our ongoing systematic examination after a rigorous three-level screening approach. Subsequently, a comprehensive analysis of the complete text was conducted, and additional scrutiny was given to these articles. Conclusion: Despite being mostly unknown, the relationship between vitamin D and POAG is particularly intriguing because, when taken as directed, vitamin D is a reasonably priced and safe supplement. It seems that vitamin D protects against oxidative damage and the generation of reactive oxygen species (ROS). Consequently, hypotheses linking vitamin D to POAG include the vitamin's antioxidant properties and its function in inhibiting inflammatory gene expression.
The Comprehensive Systematic Review of Traumatic Brain Injury and Visual Disorders Cintya Ristimawarni; Kaharuddin Yunus; Nazza Rizky Ramdhagama
The International Journal of Medical Science and Health Research Vol. 8 No. 3 (2025): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/ktc29w90

Abstract

Background: Traumatic brain injury (TBI) is a leading cause of death and disability globally, affecting predominantly children, young people, and the elderly. Complications include concussions, focal injuries, and diffuse damage. Visual impairments caused by traumatic brain injury can have an influence on quality of life and functional independence. Understanding the relationship between TBI and visual abnormalities is critical for creating effective diagnostic tools and treatment plans. Methods: This systematic review followed PRISMA 2020 guidelines, concentrating solely on full-text articles published in English from 2014 to 2024. Editorials and review articles lacking a DOI were excluded to ensure the use of high-quality sources. A literature review was performed using reputable databases such as ScienceDirect, PubMed, and SagePub to identify pertinent studies. Result: The preliminary database search revealed more than 200 relevant papers on the subject. Following a comprehensive three-stage screening process, eight studies were selected that met the specified inclusion criteria for in-depth analysis. The research were subjected to rigorous critical assessment, enabling an in-depth analysis of traumatic brain injury and visual disorders. This focused approach ensured that the analysis employed strong evidence closely linked with the study's objectives. Conclusion: TBI patients often experience visual dysfunctions, affecting their outcomes. The severity and type of injury significantly influence these issues. Comprehensive eye examinations are crucial for detecting subtle impairments, and long-term monitoring and rehabilitation strategies are essential for improved patient care.