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All Journal JURNAL ILMIAH OBSGIN : Jurnal Ilmiah Ilmu Kebidanan & Kandungan Jurnal Medicare Health Care : Journal of Community Service
Dwi Lestari, Yusri
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Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Nursing Public Health

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Peran Genetik dan Lingkungan dalam Diabetes Gestasional: Systematic Review Dwi Lestari, Yusri; Ayu Wulandari, Putri
JURNAL ILMIAH OBSGIN : Jurnal Ilmiah Ilmu Kebidanan & Kandungan P-ISSN : 1979-3340 e-ISSN : 2685-7987 Vol 16 No 4 (2024): DESEMBER
Publisher : NHM PRESS

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Abstract

Gestational diabetes mellitus (GDM) is a condition that arises during pregnancy due to impaired glucose metabolism. Its development is influenced by a complex interaction between genetic and environmental factors. Genetic factors, such as insulin resistance and glucose metabolism, alongside environmental influences including diet, physical activity, air pollution, and stress, play significant roles in increasing GDM risk. This analysis is based on a literature review examining the relationship between genetic factors, environmental factors, and their interaction in GDM risk. The review includes data from studies on lifestyle, environmental exposures, and underlying genetic mechanisms contributing to GDM development. Research indicates that unhealthy lifestyles, such as high-fat diets and physical inactivity, significantly exacerbate GDM risk in individuals with a genetic predisposition. Environmental exposures, such as air pollution and stress, further deteriorate glucose metabolism through epigenetic changes. These interactions demonstrate that both genetic and environmental factors simultaneously contribute to the elevated risk of GDM. A deeper understanding of the interplay between genetic and environmental factors offers valuable insights for the prevention and management of GDM. Personalized strategies emphasizing healthy lifestyles and mitigating environmental exposures could be effective approaches, particularly for individuals with high genetic risk.
Pengaruh diabetes gestasional terhadap perkembangan otak janin: systematic review Dwi Lestari, Yusri; Zerlina Elysia, Naflah
JURNAL ILMIAH OBSGIN : Jurnal Ilmiah Ilmu Kebidanan & Kandungan P-ISSN : 1979-3340 e-ISSN : 2685-7987 Vol 16 No 4 (2024): DESEMBER
Publisher : NHM PRESS

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Gestational diabetes mellitus (GDM) has been identified as having a significant impact on fetal brain development. The underlying mechanisms involve a combination of biological, environmental, and lifestyle factors. This study aims to evaluate findings from ten journal articles related to GDM and its influence on fetal brain development. A systematic review was conducted on ten selected journal articles, focusing on the effects of GDM on cognitive and motor development, structural brain changes, and risk factors exacerbating the condition. The review revealed that GDM can lead to delays in cognitive and motor development in children and structural changes in fetal brain regions associated with executive and motor functions. Factors such as oxidative stress, inflammation, maternal obesity, and high-calorie diets were found to worsen the effects of GDM through insulin resistance and disrupted neurogenesis. Additionally, poor maternal sleep quality, psychological stress, and lack of social support were shown to increase the risk of fetal developmental disorders. Intervention studies highlighted the potential to mitigate these risks through balanced diets and effective glucose management. These findings underscore the importance of a holistic approach to mitigating the adverse effects of GDM on fetal brain development. This approach includes metabolic control, healthy lifestyles, stress management, and early interventions. Further research is necessary to explore preconception prevention strategies, long-term interventions, and multifactorial influences on fetal development risks.
Efektivitas Edukasi Berbasis Multimedia dan Suplementasi Zat Besi terhadap Pengetahuan Anemia dan Kadar Hemoglobin pada Santri Perempuan Kelas VII di SMP Nurul Jadid Dwi Lestari, Yusri; Ahmad Kholid Fauzi
Jurnal Medicare Vol. 4 No. 3: JULY 2025
Publisher : Rena Cipta Mandiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62354/jurnalmedicare.v4i3.194

Abstract

Anemia is one of the common health problems affecting adolescent girls, including those in Islamic boarding school (pesantren) environments, which have distinctive lifestyle and learning patterns. Low levels of knowledge and poor adherence to iron supplementation are major contributors to the high prevalence of anemia in this population. This study aimed to analyze the effectiveness of animation-based education and iron tablet supplementation on improving knowledge and hemoglobin levels among seventh-grade female students at SMP Nurul Jadid. A quasi-experimental design with a pretest-posttest approach without a control group was used, involving 45 students selected from one of five classes through purposive sampling. The intervention consisted of educational sessions using animated videos covering topics on adolescent nutrition, anemia, and the importance of iron tablet consumption, alongside the provision of one iron tablet per week over a six-month period. Data were collected through a knowledge questionnaire and hemoglobin measurements before and after the intervention, and analyzed using a paired t-test. The results showed a significant improvement in both knowledge (p = 0.001) and hemoglobin levels (p = 0.002). Therefore, animation-based education combined with iron tablet supplementation is proven effective in enhancing nutritional and anemia-related knowledge and in increasing hemoglobin levels among adolescent girls.
Deteksi Dini Risiko Diabetes Melitus melalui Pemeriksaan Gula Darah pada Remaja Putri Dwi Lestari, Yusri; Ahmad Kholid Fauzi
Health Care : Journal of Community Service Vol. 3 No. 2 (2025)
Publisher : Rena Cipta Mandiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62354/healthcare.v3i2.112

Abstract

The rising prevalence of Type 2 Diabetes Mellitus among young populations is becoming an alarming public health issue. One of the key contributing factors is the lack of awareness and delayed early detection, particularly among adolescent girls who are vulnerable to unhealthy lifestyle changes. This community service project aimed to perform early detection of type 2 diabetes melitus risk through random blood glucose screening and interactive health education for seventh-grade female students at SMP Nurul Jadid. The method involved random blood glucose testing using calibrated digital glucometers on 42 participants, followed by health education sessions through lectures and discussions, and evaluation using pretest and posttest questionnaires. Results showed that 21.4% of participants were in the prediabetes category, while the average knowledge score increased significantly from 56.2 to 92.6 after the education session. Participants also demonstrated high levels of active engagement and interest in health-related topics. These findings highlight the importance of early detection and school-based health education in preventing type 2 diabetes melitus. This activity proved effective in improving students' knowledge and awareness and holds strong potential to be developed into a sustainable preventive health program within the educational environment.
Co-Authors Ahmad Kholid Fauzi Ayu Wulandari, Putri Zerlina Elysia, Naflah