Article Per Year (5 Year)
p-Index From 2020 - 2025
0.61
P-Index
This Author published in this journals
All Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Kesehatan Jurnal Penelitian Pendidikan, Psikologi Dan Kesehatan (J-P3K)
Nasution, Atika Rimalda
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Health Professions Materials Science & Nanotechnology Nursing Physics Public Health Social Sciences

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
Sunscreen Effect of Andaliman Methanol Extract Nano Gel on The Amount of Melanin in Wistar Rats Exposed to UV-B Light Vera, Vera; Chiuman, Linda; Ginting, Chrismis Novalinda; Nasution, Atika Rimalda; Bangun, Chrismas Gideon; Bangun, Primta
Jurnal Kesehatan Vol 15 No 3 (2024): Jurnal Kesehatan
Publisher : Poltekkes Kemenkes Tanjung Karang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jk.v15i3.4486

Abstract

Excessive exposure to UV-B rays can increase melanin production, potentially causing skin damage, making it necessary to prevent this through the use of natural-based sunscreens, such as nano gel from methanol extract of andaliman, to protect the skin from the harmful effects of UV-B radiation. This study aims to evaluate the sunscreen effect of andaliman methanol extract nanogel on the amount of melanin in Wistar rats exposed to UV-B light. The method used was a laboratory experimental study with a randomized posttest only with a control group design using mice as the research subjects. The results of the study showed that the SPF values of andaliman extract at concentrations of 2%, 3.5%, and 5% were 2.11, 2.49, and 2.45, respectively, which are considered low for sunscreen protection standards. Additionally, the amount of melanin obtained from each treatment group was also categorized as small, indicating that the andaliman extract in nano gel form did not significantly reduce melanin production in Wistar rats exposed to UV-B rays. In conclusion, there is no sunscreen effect of andaliman methanol extract nanogel on the amount of melanin in Wistar rats exposed to UV-B light. This could be due to factors such as the low SPF value, the lack of stability of the active ingredients in the nano gel, or the need for an increased dosage. The implications of these findings suggest the need for further research to optimize the formulation or explore other more effective ingredients in preventing melanin production caused by UV-B exposure.
Pengaruh Pemberian Gel Ekstrak Daun Buncis (Phaseolus Vulgaris L.) Sebagai Anti-Inflamasi Penyembuhan Luka Bakar Tikus Putih (Rattus norvegicus) Galur Wistar Ahdiah, Amalia; Nasution, Atika Rimalda; Nelda, Fitri
JURNAL PENELITIAN PENDIDIKAN, PSIKOLOGI DAN KESEHATAN (J-P3K) Vol 6, No 2 (2025): J-P3K
Publisher : Yayasan Mata Pena Madani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51849/j-p3k.v6i2.616

Abstract

Penelitian ini bertujuan untuk mengetahui pengaruh pemberian gel ekstrak daun buncis (Phaseolus vulgaris L.) sebagai agen anti-inflamasi dalam penyembuhan luka bakar pada tikus putih (Rattus norvegicus) galur Wistar. Luka bakar dapat menyebabkan peradangan yang menghambat proses penyembuhan, sehingga dibutuhkan agen yang dapat mengurangi inflamasi dan mempercepat penyembuhan luka. Ekstrak daun buncis diketahui mengandung senyawa aktif yang memiliki efek anti-inflamasi dan dapat mendukung proses regenerasi jaringan. Pada penelitian ini, tikus putih galur Wistar dibagi menjadi beberapa kelompok, yang masing-masing diberikan perlakuan luka bakar dan pemberian gel ekstrak daun buncis. Setelah periode pengobatan tertentu, dilakukan evaluasi terhadap perubahan kadar inflamasi dan tingkat penyembuhan luka. Hasil penelitian menunjukkan bahwa pemberian gel ekstrak daun buncis secara signifikan dapat mengurangi inflamasi dan mempercepat proses penyembuhan luka bakar pada tikus putih. Temuan ini menunjukkan potensi ekstrak daun buncis sebagai agen terapi anti-inflamasi dalam penyembuhan luka bakar.
The Effect of Andaliman Fruit Extract (Zanthoxylum acanthopodium DC) on α-Synuclein Levels in Rotenon-Induced Wistar Rats Maulidza, Citra Puan; Halim, Binarwan; Chiuman, Linda; Nasution, Atika Rimalda; Theresia, Yohani
Jurnal Penelitian Pendidikan IPA Vol 11 No 2 (2025): February
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i2.10362

Abstract

Parkinson's disease is a neurodegenerative disorder characterized by loss of dopamine and formation of α-synuclein aggregates in the substantia nigra pars compacta (SNpc). This study aims to evaluate α-synuclein levels in the plasma of rotenone-induced Wistar rats as a model of Parkinson's disease and the therapeutic effect of Andaliman fruit extract. The design of this study was experimental with 25 male Wistar rats divided into five groups, negative control group (K-, only given distilled water), positive control (K+, induced rotenone 3 mg/kgBB/day for two weeks), and three treatment groups (P1, P2, P3) induced rotenone and given Andaliman extract orally at a dose of 150 mg/kgBB, 300 mg/kgBB, and 450 mg/kgBB respectively for 14 days. Measurement of levels was performed using ELISA on day 14 after induction and day 28 after therapy. The results of one-way ANOVA analysis showed that Andaliman extract significantly reduced α-synuclein levels at all doses compared to the positive control (p=0.000). The decrease in α-synuclein levels indicates the potential of Andaliman fruit extract in reducing Parkinson's disease-related pathology in mouse models.
Co-Authors Ahdiah, Amalia Bangun, Chrismas Gideon Bangun, Primta Binarwan Halim Chiuman, Linda Ginting, Chrismis Novalinda Maulidza, Citra Puan NELDA, FITRI Theresia, Yohani vera vera, vera