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All Journal International Journal of Integrated Health Sciences eScience Humanity Journal Research Horizon
Takaryanto, Davin
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Arts Humanities Economics, Econometrics & Finance Education Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Social Sciences

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Ifosfamide-Induced Encephalopathy in Relapsed Lymphoma: Report of Two Cases Takaryanto, Davin; Harti, Gusti Fungani; Oehadian, Amaylia
International Journal of Integrated Health Sciences Vol 12, No 2 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v12.n2.3558

Abstract

Objective: Ifosfamide is a chemotherapeutic drug available for various malignancy, including lymphoma. Ifosfamide has adverse effects including myelosuppression, nephrotoxicity, hemorrhagic cystitis, and neurotoxicity. Encephalopathy is a severe manifestation of neurotoxicity due to ifosfamide, with an incidence of 10–40%. This study aimed to report two cases of ifosfamide-induced encephalopathy.Case: This case studies reported two relapsed lymphoma patients with almost similar characteristics who received ifosfamide chemotherapy. The first case of 48-year-old woman with relapsed High-Grade B-cell lymphoma stage IIIBE while the second case of 38-year-old woman with relapsed non-hodgkin lymphoma. The first case showed a good outcome with improvement in consciousness 48 hours after stopping ifosfamide and thiamine, while the second case experienced tumor lysis syndrome, leading to the death of the patient.Conclusion: Mechanism of ifosfamide-induced encephalopathy remains unclear, with the hypothesis from the neurotoxic effects of the resultant metabolite chloracetyldehide. Radiology examination of the brain and electroencephalography is required to rule out other differential diagnoses. Early recognition of adverse effects, followed by immediate discontinuation of ifosfamide, administration of therapy, such as methylene blue and/or thiamine, and supportive treatment usually produced good outcomes.
Juridical Analysis of Business Dispute Resolution in Strategic Technology and Services Procurement Contract Disputes through the Indonesian National Arbitration Board (BANI) Hamdan, Angkasa Ramatuan; Nugroho, Enggar Adi; Takaryanto, Davin; Ciptawan STP, Beni; Syahruddin, Syahruddin; Anggraeni, Happy Yulia
eScience Humanity Journal Vol 5 No 2 (2025): eSience Humanity vol 5.2. May 2025
Publisher : Asosiasi Ide Bahasa Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37296/esci.v5i2.262

Abstract

This research examines legal issues arising from business disputes in contractual agreements, specifically focusing on the Availability Payment (AP) Service Level Agreement (SLA) between PT Palapa Ring Barat and the Ministry of Communication and Informatics of the Republic of Indonesia. Disputes emerged due to differing interpretations of tax clauses, where PT Palapa Ring Barat demanded additional VAT (10%) on AP payments, while Kemenkominfo argued the payments already included VAT. This study employs a normative juridical method, analyzing primary sources such as BANI Decision No. 45016/II/ARB-BANI/2022 and relevant legal frameworks, including Law No. 30 of 1999 on Arbitration and Alternative Dispute Resolution. Findings indicate that arbitration plays a critical role as an effective, binding dispute resolution mechanism, as demonstrated by BANI's decision, which affirmed the validity of the agreement and ordered Kemenkominfo to pay additional VAT. The case highlights the importance of clear contractual clauses, particularly regarding taxation, to prevent disputes. In comparison, other dispute resolutions, such as mediation, are evident in cases like the collaboration between RSUD Mataram and CV. Ijen Perkasa on hospital information system management. This research contributes to the field by emphasizing the need for clear, comprehensive contracts and effective dispute resolution mechanisms. The findings provide insights for businesses and policymakers to develop contracts that minimize potential conflicts while promoting adherence to legal frameworks
Legal Protection of Personal Data in the Exchange of Electronic Medical Record in Healthcare Services Takaryanto, Davin; Lany, Arman
Research Horizon Vol. 5 No. 6 (2025): Research Horizon - December 2025
Publisher : LifeSciFi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54518/rh.5.6.2025.897

Abstract

Digital transformation in Indonesia’s health sector has fundamentally changed the way patient information is collected, stored, and managed through Electronic Medical Records (EMR). This study aims to (1) map the active legal basis governing the confidentiality of EMRs in Indonesia; (2) identify normative and practical gaps in its implementation; (3) propose auditable technical and governance standards for healthcare facilities and system providers; and (4) outline procedural and judicial mechanisms for resolving health data breach disputes. Using a normative legal approach, this study analyzes the constitutional, legislative, and regulatory legal framework, such as Law Number 17 of 2023 concerning Health, Law Number 27 of 2022 concerning Personal Data Protection, Law Number 1 of 2024 concerning Electronic Information and Transactions, Government Regulation Number 71 of 2019, and Minister of Health Regulation Number 24 of 2022. The results of the study show overlapping authorities, weak institutional coordination, and the absence of procedural standards related to the verification of RME in court. The study’s findings reveal that EMR confidentiality protection in Indonesia is weak not due to a lack of legal regulations, but due to inadequate technical readiness and governance for its implementation.
Co-Authors Amaylia Oehadian Angkasa Ramatuan Hamdan Arman Lany, Arman Ciptawan STP, Beni Happy Yulia Harti, Gusti Fungani Nugroho, Enggar Adi Syahruddin Syahruddin