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All Journal Jurnal An-Najat: Jurnal Ilmu Farmasi dan Kesehatan
Salma Fitriyanti
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Dentistry Health Professions Nursing Public Health Veterinary

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Implementasi Sistem ISO 14001 dalam Pengelolaan Limbah Industri Farmasi di Indonesia Hairunnisa Hairunnisa; Salma Fitriyanti; Nor Latifah
An-Najat Vol. 3 No. 3 (2025): Agustus : An-Najat : Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v3i3.3119

Abstract

This review explores the implementation of ISO 14001 in pharmaceutical waste management within Indonesia’s industry context. ISO 14001, as an Environmental Management System (EMS), offers a structured approach to reducing environmental risks and improving operational efficiency. The review analyzes five peer-reviewed articles published between 2023 and 2025, focusing on hospitals and pharmaceutical-related sectors. Findings reveal that ISO 14001 adoption contributes significantly to better waste segregation, reduced environmental impact, and enhanced organizational sustainability when implemented comprehensively. However, challenges such as lack of cross-unit coordination, limited policy support, and inadequate staff training hinder full system integration. The review also identifies the synergy of ISO 14001 with other standards such as ISO 45001 and ISO 22000 as a strategic advantage for industry-wide performance. Implications suggest the need for stronger regulatory frameworks and internal organizational commitment to transform ISO 14001 from a compliance tool into a driver of sustainable innovation.
Review: Perbedaan Penggunaan Pelarut Terhadap Nilai Rendemen yang Dihasilkan dengan Berbagai Metode Ekstraksi dalam Proses Ekstraksi Nur Latipah Sulistiawanti; Hairunnisa Hairunnisa; Niken Widya Ningrum3; Salma Fitriyanti
An-Najat Vol. 3 No. 3 (2025): Agustus : An-Najat : Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v3i3.3169

Abstract

The extraction process plays a crucial role in isolating bioactive compounds from natural materials. The success of the extraction process is heavily influenced by the type of solvent used and the extraction method applied. This review aims to evaluate the impact of solvents with varying polarities—both polar and non-polar—and compare the efficiency of various extraction techniques, such as Soxhlet extraction, reflux, and Ultrasonic Assisted Extraction (UAE) in obtaining extracts from various medicinal plants. Based on a review of previous studies, polar solvents generally yield higher rendemen compared to non-polar solvents, although non-polar solvents are more effective in selectively extracting non-polar compounds. Therefore, the selection of solvents should be tailored to the type of compound to be extracted to achieve optimal results. The UAE method has been proven to be more efficient than conventional extraction techniques, such as Soxhlet and reflux. The use of ultrasonic waves in UAE enhances solvent penetration into plant cells, resulting in higher yields in a shorter time. Several factors also significantly affect the extraction results, such as the solvent-to-material ratio, extraction time, and temperature. Variations in these three factors can lead to significant differences in both the quantity and quality of the extract obtained. Overall, choosing the right solvent and extraction method is essential for achieving optimal extraction results. By using solvents suited to the properties of the target compounds and selecting the most efficient method, the resulting extracts can be of higher quality and quantity. Therefore, further laboratory research is necessary to apply these findings in developing extraction methods that are not only effective but also environmentally friendly, particularly on an industrial scale. Future research could also focus on developing extraction methods that reduce the use of harmful solvents and enhance the sustainability of the extraction process at an industrial scale.
Co-Authors Hairunnisa Hairunnisa Niken Widya Ningrum3 Nor Latifah Nur Latipah Sulistiawanti