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All Journal Klinikal Sains (Jurnal Analis Kesehatan) Journal of Innovation Research and Knowledge
Meka Faizal Farabi
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Social Sciences

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UJI EFEKTIVITAS SEDIAAN GEL KOMBINASI EKSTRAK DAUN KELOR (Moringa oleifera L.) DAN MINYAK SEREH (Cimbopogan citratus) TERHADAP BAKTERI Staphylococcus aureus ATCC 25923 Elisa Issusilaningtyas; Nikmah Nuur Rochmah; Meka Faizal Farabi
Journal of Innovation Research and Knowledge Vol. 4 No. 7: Desember 2024
Publisher : Bajang Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53625/jirk.v4i7.9136

Abstract

Penelitian ini bertujuan untuk menguji efektivitas sediaan gel kombinasi ekstrak daun kelor (Moringa oleifera L.) dan minyak sereh (Cimbopogon citratus) terhadap bakteri Staphylococcus aureus ATCC 25923. Pengujian dilakukan menggunakan metode sumuran, dengan formula gel yang terdiri atas tiga konsentrasi ekstrak daun kelor (5%, 10%, dan 20%) serta minyak sereh sebesar 2%. Sebagai kontrol positif digunakan klindamisin, sementara kontrol pembanding berupa gel tanpa zat aktif, dan kontrol negatif menggunakan aquades steril. Hasil penelitian menunjukkan bahwa sediaan gel kombinasi menghasilkan zona hambatan dengan kategori "kuat" untuk semua formula, masing-masing sebesar 10,6 mm (F1), 11 mm (F2), dan 12 mm (F3). Kontrol positif klindamisin menunjukkan aktivitas "sangat kuat" dengan zona hambatan 20,7 mm, sementara minyak sereh sendiri menghasilkan zona hambatan yang lebih besar (27 mm) dibandingkan kombinasi dengan ekstrak daun kelor. Analisis statistik menunjukkan tidak adanya perbedaan signifikan antara formula gel (p = 0,058).
PERBANDINGAN KADAR HEMOGLOBIN, GLUKOSA DARAH, DAN LEUKOSIT SEBELUM DAN SESUDAH HEMODIALISA PADA PASIEN GAGAL GINJAL KRONIS KOMORBID DAN NON KOMORBID DIABETES MELLITUS DI RSPC Risma Adzkia Putri; Ira Pangesti; Meka Faizal Farabi
Klinikal Sains : Jurnal Analis Kesehatan Vol. 12 No. 2 (2024): Desember
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/klinikal_sains.v12i2.4956

Abstract

Chronic Kidney Disease (CKD) is an impairment of the glomerular organ function of the kidneys. The process of blood purification by collecting waste is called hemodialysis. The prevalence of CKD increased from 1990 to 2017 globally by 21.3% and the mortality rate increased by 41.5%. The purpose of this study was to compare hemoglobin, leukocyte, and blood glucose levels before and after hemodialysis in patients with and without comorbid Diabetes Mellitus (DM) at Pertamina Cilacap Hospital (RSPC). The method used was cross sectional using univariate and bivariate analysis with JASP program. The results showed that in CKD patients without DM, hemoglobin levels were significantly different (p<0.05) after hemodialysis. While leukocyte and glucose levels had no significant difference (p>0.05). In CKD patients with DM, there is a significant difference in hemoglobin levels (p<0.05) after hemodialysis. In addition, there is a significant difference in glucose levels (p<0.05) after hemodialysis. Meanwhile, there was no significant difference in leukocyte levels (p>0.05). Comparison of pre and post hemodialysis between CKD without DM and CKD with DM there is a significant difference (p<0.05) in hemoglobin and blood glucose levels but there is no significant difference (p>0.05) in leukocyte levels.
Co-Authors Elisa Issusilaningtyas Ira Pangesti Nikmah Nuur Rochmah Risma Adzkia Putri