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Peran suplementasi asam folat pada masa kehamilan sebagai strategi preventif terhadap risiko neural tube defects Kinasih, Prananingrum; Jannah, Miftahul; Zetta, Adelia Paradya; Anshari, Alfirqan; Walter, Beatrice Cynthia
Holistik Jurnal Kesehatan Vol. 19 No. 7 (2025): Volume 19 Nomor 7
Publisher : Program Studi Ilmu Keperawatan-fakultas Ilmu Kesehatan Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/hjk.v19i7.1082

Abstract

Background: Neural tube defects (NTDs) are congenital abnormalities of the central nervous system that result from failure of the neural tube to close during embryonic development. They can cause permanent disability or death, and are a significant public health problem, especially in developing countries. Purpose: To review the role of folic acid supplementation during pregnancy as a preventive strategy against the risk of neural tube defects. Method: This study was a literature review using the narrative method. Selected articles published between 2020 and 2025 were reviewed, obtained from PubMed and ScienceDirect databases. Results: Folic acid consumption of 400 microgram per day can reduce the risk of NTDs by 50-70%. However, public compliance with folic acid consumption remains low due to lack of awareness, limited access, and lack of mandatory fortification policies in many countries. In addition, education and socioeconomic factors affect the level of knowledge and supplement consumption. Conclusion: Folic acid supplementation is an effective preventive strategy in reducing the incidence of NTDs. In addition to preventing NTDs, folic acid supplementation during pregnancy can reduce the risk of pregnancy complications and support fetal development.   Keywords: Folic Acid; Neural Tube Defects; Pregnancy; Supplementation.   Pendahuluan: Neural Tube Defects (NTD) adalah kelainan bawaan pada sistem saraf pusat yang terjadi akibat kegagalan penutupan tabung saraf selama perkembangan embrio. Kelainan ini dapat menyebabkan kecacatan permanen atau kematian, dan menjadi masalah kesehatan masyarakat yang signifikan, terutama di negara berkembang. Tujuan: Untuk mereview peran suplementasi asam folat pada masa kehamilan sebagai strategi preventif terhadap risiko neural tube defects (NTD). Metode: Penelitian ini merupakan literature review dengan metode naratif. Dikaji beberapa artikel terpilih yang dipublikasikan antara tahun 2020 hingga 2025, diperoleh dari basis data PubMed dan ScienceDirect. Hasil: Menunjukkan bahwa konsumsi asam folat sebesar 400 mikrogram per hari dapat menurunkan risiko NTD hingga 50-70%. Namun, tingkat kepatuhan masyarakat terhadap konsumsi asam folat masih rendah karena kurangnya kesadaran, akses terbatas, dan minimnya kebijakan fortifikasi wajib di banyak negara. Selain itu, faktor pendidikan dan sosial ekonomi memengaruhi tingkat pengetahuan dan konsumsi suplemen. Simpulan: Suplementasi asam folat merupakan strategi preventif yang efektif dalam menurunkan angka kejadian NTD. Selain dapat mencegah NTD, suplementasi asam folat pada masa kehamilan dapat menurunkan risiko komplikasi kehamilan dan mendukung perkembangan janin.   Kata Kunci: Asam Folat; Kehamilan; Neural Tube Defects; Suplementasi.
Narrative review: Ultra-processed foods and the risk of metabolic syndrome Kinasih, Prananingrum; Jannah, Miftahul
AcTion: Aceh Nutrition Journal Vol 11, No 1 (2026): March
Publisher : Department of Nutrition at the Health Polytechnic of Aceh, Ministry of Health

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/action.v11i1.3017

Abstract

Ultra-processed foods generally contain high levels of energy, sugar, sodium, and saturated fat, and low levels of fiber and micronutrients. Excessive consumption of ultra-processed foods can potentially trigger metabolic dysfunction via inflammatory pathways, insulin resistance, and lipid homeostasis disorders. This study aimed to review the scientific evidence regarding the relationship between ultra-processed food consumption and the risk of metabolic syndrome. This narrative literature review was conducted using a systematic search of the PubMed and ScienceDirect databases (2020–2025). The inclusion criteria were observational studies on related topics, articles in English, and full texts, while the exclusion criteria were studies on animals/cell cultures and non-full-text articles. The results of this study showed a consistent relationship between UPF consumption and an increased risk of metabolic syndrome. Individuals in the highest quartile of UPF consumption were 3.27 times more likely to develop metabolic syndrome (OR=3.27; 95% CI: 2.76–3.89; p<0.001). Additionally, high UPF consumption was associated with increased weight, BMI, waist circumference, blood pressure, fasting blood glucose, HbA1c levels, and triglyceride levels. In conclusion, high UPF consumption consistently increases the risk of metabolic syndrome; therefore, limiting UPF and improving the diet may be a preventive strategy.
Peningkatan Literasi Mahasiswa tentang Ultra Processed Food dan Sedentary Lifestyle melalui Forum Diskusi Ilmiah Kinasih, Prananingrum; Miftahul Jannah; Adelia Paradya Zetta; Beatrice Cynthia Walter
JURNAL AKADEMIK PENGABDIAN MASYARAKAT Vol. 4 No. 3 (2026): Mei
Publisher : CV. KAMPUS AKADEMIK PUBLISING

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61722/japm.v4i3.9925

Abstract

Changes in modern lifestyles have driven the emergence of a dual epidemic characterized by increased consumption of ultra-processed foods (UPF) and a sedentary lifestyle. As a productive age group, college students are at high risk for both of these factors due to unhealthy activity patterns and consumption habits. This scientific discussion forum aims to improve students’ literacy regarding UPF and sedentary lifestyles. The method used was an interactive discussion involving faculty members as resource persons and students as participants. The activity was held on November 14, 2025, in the video conference (ViCon) room at Batam International University with 24 participants. The results of the activity showed an increase in students’ knowledge and awareness regarding the characteristics of UPF, its impact on health, and the risks of a sedentary lifestyle. Students also demonstrated a critical attitude in choosing consumption patterns and began to realize the importance of physical activity. The conclusion of this activity is that scientific discussion forums are effective as an educational medium in improving student literacy regarding the double epidemic and strengthening the role of students as agents of change in implementing and disseminating healthy lifestyle behaviors. Keywords: health education; sedentary lifestyle; student literacy; ultra processed food.   Abstrak Perubahan gaya hidup modern telah mendorong terjadinya fenomena epidemi ganda yang ditandai dengan meningkatnya konsumsi UPF dan sedentary lifestyle. Mahasiswa sebagai kelompok usia produktif memiliki risiko tinggi terhadap kedua faktor tersebut akibat pola aktivitas dan kebiasaan konsumsi yang kurang sehat. Kegiatan forum diskusi ilmiah ini bertujuan untuk meningkatkan literasi mahasiswa terkait UPF dan sedentary lifestyle. Metode yang digunakan adalah diskusi interaktif yang melibatkan dosen sebagai narasumber dan mahasiswa sebagai peserta. Kegiatan dilaksanakan pada 14 November 2025 di ruang video conference (ViCon) Universitas Internasional Batam dengan jumlah peserta sebanyak 24 orang. Hasil kegiatan menunjukkan adanya peningkatan pengetahuan dan kesadaran mahasiswa terkait karakteristik UPF, dampaknya terhadap kesehatan, serta risiko sedentary lifestyle. Mahasiswa juga menunjukkan sikap yang kritis dalam memilih pola konsumsi dan mulai menyadari pentingnya aktivitas fisik. Kesimpulan dari kegiatan ini adalah forum diskusi ilmiah efektif sebagai media edukasi dalam meningkatkan literasi mahasiswa mengenai epidemi ganda serta memperkuat peran mahasiswa sebagai agen perubahan dalam menerapkan dan menyebarluaskan perilaku hidup sehat. Kata kunci: edukasi kesehatan; literasi mahasiswa; sedentary lifestyle; ultra processed food.