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All Journal Falah : Jurnal Ekonomi Syariah Jurnal Riset Kesehatan Poltekkes Depkes Bandung
Luqman, Arif
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Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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The Effect of Transparency and Accountability on Muzakki's Trust in the Amil Zakat Institution: Case Study on the Ash Shohwah Social Charity Foundation Malang Sholihah, Hannysa Rohmatul; Luqman, Arif; Hakim, Rahmad
Falah: Jurnal Ekonomi Syariah Vol. 9 No. 2 (2024): AUGUST
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/jes.v9i2.37160

Abstract

The purpose of this study was to determine the influence of transparency and accountability of financial reports on muzakki’s trust in the Amil Zakat Institution, Ash-Shohwah Malang Social Charity Foundation. The method in this research uses a quantitative by applying a questionnaire to 100 respondents who are permanent muzakki from 2020-2023 at the Amil Zakat Institute, Ash-Shohwah Social Charity Foundation Malang. The sample od this study was purposive sampling and hypothesis testing and analysing by the SmartPLS 4.0 tool. The results found that the transparency variable had a significant effect on muzakki's trust in the Amil Zakat Institution, Ash Shohwah Social Charity Foundation, Malang. The accountability variable has a significant effect on muzakki's trust in the Amil Zakat Institution, Ash Shohwah Social Charity Foundation, Malang. This study contribute to the cooperation between zakat management institutions, educational institutions, and stakeholders to increase the willingness to pay for zakat donator to zakat institutions.
Analisis Penambatan Molekuler Hidrokarbon Seskuiterpen Gaharu Merauke terhadap protein pengikat penisilin pada Acinetobacter baumanii Prasetya, Yulianto Ade; Luqman, Arif
JURNAL RISET KESEHATAN POLTEKKES DEPKES BANDUNG, Online ISSN 2579-8103 Vol 18 No 1 (2026): Jurnal Riset Kesehatan Poltekkes Depkes Bandung
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/juriskesbdg.v18i1.3219

Abstract

Background: Acinetobacter baumannii is a critical nosocomial pathogen associated with a high level of antibiotic resistance, necessitating the exploration of alternative antibacterial candidates from natural sources. Merauke agarwood (Aquilaria malaccensis) essential oil contains various sesquiterpenes; however, molecular-level evidence targeting A. baumannii penicillin-binding proteins (PBPs) remains limited. Objective: This study evaluated the interactions of selected sesquiterpene hydrocarbons, γ-cadinene, kessane, and α-gurjunene, from Merauke agarwood using an in silico approach. Methods: Drug-likeness and ADMET properties were predicted using ADMETLab 3.0, while potential biological activities were assessed with PASS Online. Molecular docking was performed against A. baumannii PBP1a (3UE3) and PBP3 (3UDF) using CB-Dock2, followed by protein–ligand interaction analysis with PLIP. Results: All compounds complied with Lipinski’s rule and showed moderate quantitative estimates of drug-likeness, although high lipophilicity and plasma protein binding were predicted. Docking analysis revealed moderate binding affinities toward both PBPs (−6.2 to −6.7 kcal/mol) and identified conserved hydrophobic interaction regions involving recurrent amino acid residues within each protein. PASS predictions indicated higher probabilities of antibacterial-related activity than inactivity for all ligands Conclusions: These sesquiterpene hydrocarbons from agarwood form stable interactions with A. baumannii PBPs, providing a structural basis for lead scaffolds in structure-based screening. Further studies on oxygenated derivatives, formulation strategies, and experimental validation are recommended. These sesquiterpene hydrocarbons from agarwood form stable interactions with A. baumannii PBPs, providing a structural basis for lead scaffolds in structure-based screening. Further studies on oxygenated derivatives, formulation strategies, and experimental validation are recommended.
Co-Authors Rahmad Hakim Sholihah, Hannysa Rohmatul Yulianto Ade Prasetya, Yulianto Ade