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All Journal Jurnal Biologi Tropis
Mardiyah, Raudatul
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology

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Hippocratic Screening of Pineapple Peel (Ananas comosus (L.) Merr) Water Extracts Alamanda, Baiq Irzana Putri; Mardiyah, Raudatul; Aini, Siti Rahmatul
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.7873

Abstract

Pineapple (Ananas comosus (L.) Merr.) is the fruit with the highest production in Indonesia, with West Nusa Tenggara as one of the largest producers. However, high pineapple production causes an increase in pineapple peel waste. Pineapple peel has potential as a traditional medicine because it contains beneficial compounds. This study aims to conduct a hypocratic screening on pineapple peel water extract to determine its pharmacological activity. The research method involved the use of Swiss Webster mice as test animals, where pineapple peel water extract was administered intraperitoneally in five doses (1, 10, 100, 300 and 1000 mg/KgBW). Observations were made on the mice's physical activity every 5 minutes for 4 hours, and continued after 2, 4, and 7 days of treatment. The results showed significant stimulant activity in the central nervous system (CNS) at certain doses, characterized by changes in the physiological activity of mice. Symptoms include increased motor activity, hyperemia, and diarrhea.
Co-Authors Aini, Siti Rahmatul Alamanda, Baiq Irzana Putri