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All Journal Indonesian Journal of Pharmaceutical Science and Technology Biology, Medicine, & Natural Product Chemistry Jurnal Kedokteran Jurnal Biologi Tropis JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Gema Ngabdi Jurnal Pengabdian Masyarakat Sains Indonesia (Indonesian Journal Of Science Community Services) Jurnal Abdi Insani Jurnal Kesehatan Tambusai Sasambo Journal of Pharmacy
Aini, Siti Rahmatul
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Penggunaan Psikotropika pada Anak dan Remaja Penderita Asma di Belanda 1999-2006 Aini, Siti Rahmatul
Jurnal Kedokteran Vol 1 No 1 (2012)
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction: To determine the association between asthma and the use of psychotropic drugs by focusing on whether the asthmatic children receive more often psychotropic drugs compared with non asthmatic children in the population based cohort design. Method: Using InterAction Database (IADB), drug dispensing data from Dutch community pharmacies (55 community pharmacies) in 1999 – 2006, children and adolescents aged 0 to 19 years in the study period (1 Januari 1999 to 31 Desember 2006 were divided into two groups; the index (asthmatic children and adolescents) and the reference (antibiotic children and adolescents) groups. We calculated the incidences of psychotropic drugs use (in both groups) and the incidence risk ratio (IRR). Results: The incidences of psychotropic drug use were 0.058 cases/1000 person-days in index group and 0.048 cases/1000 person-days in reference group. The incidence risk ratio of anti psychotropic drug use was 1.21 ( CI 1.18-1.29). Conclusions : Asthmatic patients are 1.21 times more likely than non asthmatic patients to receive psychotropic drugs over the 8 years period in this study.
Skrining fitokimia ekstrak air dan ekstrak etanol 70% Propolis Trigona sp. asal Lombok Utara Ananta, Muhammad Naufal Farras; Nuralyza, Imasayu; Solehah, Kurnia; Pratama, Iman Surya; Aini, Siti Rahmatul
Sasambo Journal of Pharmacy Vol. 5 No. 1 (2024): April
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v5i1.305

Abstract

Propolis Trigona sp. has many benefits closely related to the secondary metabolites contained therein. Previous research related to propolis screening of Trigona sp. from North Lombok has been carried out. Still, it has yet to be carried out in the maceration method (1:20 w/v) with 70% water and ethanol solvent to obtain a comparison of secondary metabolites between the two solvents. This study aims to identify the content of secondary metabolites in the water extract and 70% ethanol extract of propolis Trigona sp. from North Lombok. Propolis was macerated with water and 70% ethanol solvent. The viscous extract was identified for its physical characteristics, consistency, color, and chemical characteristics through phytochemical screening. The results of the phytochemical screening showed that the aqueous extract and 70% ethanol extract contained alkaloids, flavonoids, tannins, triterpenoids, and quinones. Both extracts showed negative saponin results.
Pharmacist Goes to School: Promoting DAGUSIBU As A Pharmaceutical Education Tool for Adolescents Saputra, Yoga Dwi; Ulya, Tuhfatul; Hasina, Raisya; Aini, Siti Rahmatul; Puspitasari, Candra Eka; Andanalusia, Mahacita; Lisnasari, Baiq Risky Wahyu; Hamdin, Candra Dwipayana
Jurnal Gema Ngabdi Vol. 6 No. 3 (2024): JURNAL GEMA NGABDI
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jgn.v6i3.522

Abstract

Drug misuse is an urgent public health issue, often arising from a lack of knowledge about proper medication use. Research shows that over half of the medications worldwide are used irrationally. The DAGUSIBU program (Dapatkan, Gunakan, Simpan, Buang or known as Get, Use, Store, Dispose) was developed as a solution to address this issue by providing education on proper medication management. This community service activity was organized by the Pharmacy Study Program and the Pharmacy Professional Education Program (PSPPA), Faculty of Medicine and Health Sciences (FKIK), Universitas Mataram, on August 9, 2024, at Kesuma Catholic High School in Mataram. The primary goal of this activity was to teach students the correct ways to obtain, use, store, and dispose of medications, as well as to introduce the pharmacist profession and the Pharmacy program at UNRAM to high school students. The activity included interactive presentations on DAGUSIBU, an introduction to the pharmacist profession, and a quiz competition as an evaluation method. The quiz encouraged active student participation, with prizes to boost motivation. Despite challenges such as varying levels of student comprehension and time constraints, the activity successfully improved students’ understanding of rational drug use and introduced career opportunities in pharmacy. Overall, this activity proved effective in raising student awareness and knowledge, positively impacting their health literacy.
In Vitro Mucolytic Activity of Cardamom Fruit (Amomum compactum) Decoction on Duck Egg Albumens Vitri, Desy Aryanti Pardilla; Aini, Siti Rahmatul; Saputri, Legis Ocktaviana
Biology, Medicine, & Natural Product Chemistry Vol 13, No 2 (2024)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2024.132.541-547

Abstract

Cardamom (Amomum compactum) is empirically used as a cough medicine by using its seeds and fruits. Cardamom seeds have been shown to have mucolytic activity at a concentration of 0.8%, while cardamom fruit has not been studied. This study aimed to determine the mucolytic activity of cardamom fruit decoction at variation concentrations. Mucolytic activity tests were carried out in vitro on duck egg albumens at 3%, 6%, and 12% variation concentrations of cardamom fruit decoction. N-acetylcysteine 0.1% was positive control, while phosphate buffer and Tween 80 were negative controls. The mucolytic activity was determined based on the viscosity value measured by flow time using an Ostwald viscometer and density measurement using a pycnometer. Data from each group were analyzed using SPSS with parametric One-Way ANOVA and Post Hoc tests. The results showed that cardamom fruit decoction at concentrations of 3%, 6%, and 12% had values that were not significantly different from N-acetylcysteine (p>0.05) and there was no significant difference (p>0.05) between each concentration group. Accordingly, the research concludes that cardamom fruit decoction at concentrations of 3%, 6%, and 12% has mucolytic activity comparable to N-acetylcysteine.
Anti –Inflammatory Activity of Propolis Trigona sp. Water Extract from North Lombok with Red Blood Cell Membrane Stability Method Humaira, Ani Fatin; Aini, Siti Rahmatul; Hasina, Raisya
Biology, Medicine, & Natural Product Chemistry Vol 13, No 2 (2024)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2024.132.555-558

Abstract

Propolis is a bee product that can be used as an anti-inflammatory. Cultivation of propolis-producing bees is also carried out in North Lombok. However, propolis has not been utilized optimally by the people of North Lombok. Apart from that, testing of North Lombok propolis is still limited to the chemical content and antioxidant activity of propolis extracted with ethanol solvent. Therefore, this study aims to determine the activity and effective concentration of North Lombok propolis water extract as an anti-inflammatory using the red blood cell membrane stability method. Groups include control groups such as positive control (diclofenac sodium), negative control (distilled water), and test groups (propolis water extract concentrations of 10%, 12.5%, 15%, 17.5%, 20%, 22.5%, 25%, 27.5%, and 30%). In The first step human blood was centrifuged of human blood, and then part of the red blood cells (sediment) was taken and saline was added to obtain a red blood cell suspension. Next, mixing the test solution was carried out in the order of 0.5 ml of red blood cell suspension, then 0.5 ml of extract was added (0.1% w/v Na-diclofenac solution in the positive control, distilled water in the negative control), 1 mL of buffer solution and 2 mL of hyposaline solution, then homogenized. Each group was incubated at 37°C for 30 minutes, then centrifuged for 10 minutes at 3000 rpm. The supernatant was taken, and the absorbance was read with a UV-Vis spectrophotometer at 560 nm. Next, the percentage value of red blood cell hemolysis protection was calculated. The data obtained were tested statistically using One-way ANOVA and post-hoc (LSD) tests SPSS version 29. The results showed that propolis water extract concentrations were 10%, 12.5%, 15%, 17.5%, 20%, 22.5%, 25%, 27.5%, and 30% have anti-inflammatory activity because they can increase the stability of the red blood cell membrane with a percentage of hemolysis protection of respectively 57.92%, 59.99%, 60.99%, 61.99%, 64.31%, 69.59%, 75.07%, 79.77% and 84.45%. Propolis water extract concentrations of 10%, 12.5%, 15%, 17.5%, 20%, 22.5%, and 25% had anti-inflammatory effects that were not significantly different from the positive control (p>0.05). The 27.5 % and 30% concentrations had a higher percent hemolysis protection value than the positive control (p<0.05).
Tingkat Pengetahuan Mahasiswa Tahun Pertama Bersama (TPB) tentang Penggunaan Antibiotik dalam Swamedikasi Fatmah, Siti; Aini, Siti Rahmatul; Pratama, iman Surya
JSFK (Jurnal Sains Farmasi & Klinis) Vol 6 No 3 (2019): J Sains Farm Klin 6(3), Desember 2019
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.6.3.200-205.2019

Abstract

Prevalensi penggunaan antibiotik dalam swamedikasi cukup tinggi di berbagai kalangan tak terkecuali mahasiswa. Penggunaan antibiotik dalam swamedikasi dapat meningkatkan resistensi antibiotik dan efek samping. Tingkat pengetahuan berpengaruh pada penggunaan  antibiotik dalam swamedikasi yang tepat dan bijak. Penelitian bertujuan untuk menggambarkan tingkat pengetahuan mahasiswa tentang penggunaan antibiotik dalam swamedikasi. Penelitian dilakukan pada bulan Maret-Juli 2018 di Unit Pelaksana Tahun Pertama Bersama Universitas Mataram menggunakan desain potong lintang. Sejumlah 400 sampel dipilih secara acak. Data karakteristik demografi dan tingkat pengetahuan diperoleh dari kuesioner yang sudah tervalidasi, kemudian dianalisis secara deskriptif. Dari 421 mahasiswal, 379 pernah menggunakan antibiotik yang terdiri dari  119 laki-laki dan 260 perempuan  dengan rata-rata usia 17-18 tahun.  Latar belakang mahasiswa sebagian besar berasal dari SMA. Hasil penelitian menunjukkan tingkat pengetahuan mahasiswa tergolong  tinggi (5,4%), sedang (63,1%), dan rendah (31,4%). Pengetahuan terkait kondisi dan dampak penggunaan antibiotik yang tidak tepat perlu diperbaiki. Tingkat pengetahuan responden tergolong sedang sehingga diperlukan peningkatan pemahaman penggunaan antibiotik yang tepat dan bijak.
Acute Toxicity Test of Pineapple Peel Aqueous Extract (Ananas comosus L.) With BSLT Method Fardiaz, Muhammad Abdurrahman; Pratama, Iman Surya; Aini, Siti Rahmatul
Indonesian Journal of Pharmaceutical Science and Technology Vol 12, No 1 (2025)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v12i1.48332

Abstract

Pineapple peel waste can be processed into pharmaceutical dosage form, but research related to the toxicity of pineapple peel is  still limited. Based on the LC50 value and the description of morphological damage in Artemia salina larvae, this study seeks to establish the acute toxicity of pineapple peel aqueous extract. The method used is the Brine Shrimp Lethality Test (BSLT). Preliminary tests were carried out using each of 10 Artemia salina larvae in 10 mL of pineapple peel water extract at concentrations of 10000;1000;100;10;1; 0.1 ppm. Based on the results of the preliminary test, the definitive test was conducted with seven concentration variations, plus a saltwater negative control and a potassium dichromate 39.06 ppm positive control. After 24 hours, observations were performed on the number of deaths and morphological damage of Artemia salina larvae. An LC50 value will be generated by performing a probit analysis on data regarding the number of larvae deaths using Microsoft Excel. A morphological damage of Artemia salina larvae were analyzed descriptively. Results of the preliminary test are presented as concentration ranges for the final test, including 100, 251, 630, 1583, 3975, 6987, and 10,000 ppm. The LC50 value obtained based on the definitive test was 1185 ppm. Morphological damage to Artemia salina larvae due to exposure to water extract of pineapple peel occurred in the antenula, appendages, abdomen, and digestive tract. Pineapple peel water extract belongs to the non-toxic category with LC50 value is > 1000 ppm. Morphological damage to Artemia salina larvae occurred at concentrations of 630-10000 ppm.
EDUKASI DAN DEMONSTRASI PEMANFAATAN TANAMAN KATANG-KATANG (IPOMOEA PES- CAPRAE) DALAM PENGOBATAN TRADISIONAL DI DUSUN MUARA PUTAT, DESA PEMENANG TIMUR, LOMBOK UTARA Hasina, Raisya; Aini, Siti Rahmatul; Hamdin, Candra Dwipayana; Ulya, Tuhfatul; Ananta, Muhammad Naufal Farras; Alamanda, Baiq Irzana Putri; Putri, Dheden Nurhani Bija; Yazid Maula
Jurnal Abdi Insani Vol 12 No 7 (2025): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v12i7.2704

Abstract

Ipomoea pes-caprae (katang-katang) adalah tanaman liar pesisir yang tersebar luas di wilayah tropis dan subtropis serta mampu beradaptasi di lingkungan berkadar garam tinggi. Perannya penting dalam ekosistem pantai, seperti mencegah erosi dan mendukung restorasi vegetasi. Daunnya umum digunakan secara tradisional untuk pengobatan gangguan pencernaan dan penyakit kulit. Di Dusun Muara Putat, Lombok Utara, tanaman ini belum dimanfaatkan secara optimal meski potensinya besar secara ekologis, terapeutik, dan ekonomis. Kegiatan ini bertujuan untuk meningkatkan wawasan dan keterampilan warga Dusun Muara Putat, Kabupaten Lombok Utara, dalam memanfaatkan katang-katang sebagai alternatif pengobatan tradisional. Pendekatan yang digunakan mencakup penyuluhan berupa sosialisasi dan praktik langsung. Kegiatan ini menggabungkan pendekatan sosialisasi dan praktik langsung, diawali dengan pre-test untuk mengukur pengetahuan awal peserta. Materi mencakup identifikasi morfologi tanaman katang-katang, kandungan bioaktif, manfaat farmakologis, dan teknik pengolahan sederhana. Peserta dilatih secara langsung, lalu dievaluasi melalui post-test untuk mengukur peningkatan pemahaman. Hasil menunjukkan peningkatan pengetahuan peserta, dengan rata-rata nilai pre-test sebesar 60 yang meningkat menjadi 80 pada post-test. Selain itu, peserta juga menunjukkan kemampuan praktik dalam mengolah tanaman untuk pengobatan rumah tangga. Penyuluhan melalui metode sosialisasi dan demonstrasi langsung dengan pendekatan partisipatif ini terbukti efektif dalam meningkatkan pengetahuan masyarakat Dusun Muara Putat tentang pengobatan tradisional, khususnya dalam pemanfaatan tanaman katang-katang (Ipomoea pes-caprae). Kesimpulannya, penyuluhan partisipatif di Dusun Muara Putat efektif meningkatkan pemahaman dan keterampilan masyarakat dalam pemanfaatan katang-katang sebagai obat tradisional.  
Nucleoside Antiviral Therapy for Herpes Zoster: A Literature Review Ain, Nisrina Huurul; Rahmatullah, Lalu Mas’ud; Utari, Widi Gustita; Nuralyza, Imasayu; Salsabiella, Baiq Rani; Maghfirahandini, Reivirly Khairadaty; Aini, Siti Rahmatul; Nurhidayati, Nurhidayati
Jurnal Biologi Tropis Vol. 25 No. 3 (2025): Juli-September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i3.10006

Abstract

Herpes zoster is a viral skin infection caused by the reactivation of the varicella-zoster virus, which remains latent in the dorsal root ganglia of the spinal cord and the cranial sensory ganglia. One of the most widely used classes of antiviral agents in the treatment of herpes zoster is nucleoside analogs. This study aims to review the use of nucleoside analogs in the management of herpes zoster. The method employed was a literature review of relevant research articles. The findings indicate that nucleoside analogs commonly used in herpes zoster therapy include acyclovir, valacyclovir, famciclovir, and brivudine. These agents are administered in various doses, routes, and therapeutic purposes, such as alleviating acute symptoms, accelerating skin lesion healing, preventing postherpetic neuralgia, and serving as prophylactic therapy in special conditions such as cancer or organ transplantation. Overall, the use of nucleoside analogs has proven effective in inhibiting varicella-zoster virus replication, reducing symptom intensity, and minimizing the risk of complications.
Pattern of Type-II Anti-Diabetes Mellitus Drug Use in Inpatients in Regional General Hospital of NTB Province in 2023 Adinda, Putri; Hasina, Raisya; Aini, Siti Rahmatul
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): in Progress
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10114

Abstract

Diabetes Mellitus is a disease with the fifth highest mortality rate in the world because it can cause serious complications such as neuropathy, nephropathy, and retinopathy. This study aims to determine the pattern of use of antidiabetic type 2 drugs in hospitalized patients at the NTB Provincial Hospital in 2023. This study was retrospective using the Probability Sampling method, namely the Simple Random Sampling type, so that a sample of 90 medical records of patients with type 2 diabetes mellitus was obtained. The data were analyzed using chi-square test using Microsoft Excel and SPSS version 25. The results of the study showed that the use of insulin antidiabetic drugs with a fast-acting insulin class was the most prescribed antidiabetic drug with a total of 603 (42.33%), while oral antidiabetic drugs with a biguanide class, namely metformin, were the most widely used oral antidiabetic drugs with a total of 246 (52.45%). Gender, age, and BMI did not significantly correlate with patient blood sugar management, according to the Chi-Square test analysis (p value > 0.05). However, the blood sugar control treatment time revealed a p value < 0.05, indicating a substantial correlation between the two variables. The study concludes that, according to the pattern of type 2 antidiabetic medication usage among hospitalized patients at the NTB Provincial Hospital in 2023, the most commonly used medications in the NTB Provincial General Hospital during that year were 603 (42.33%) insulin class antidiabetic medications, specifically rapid-acting insulin.  
Co-Authors Adinda, Putri Ain, Nisrina Huurul Alamanda, Baiq Irzana Putri Ananta, Muhammad Naufal Farras aurelia, laili Candra Eka Puspitasari Fardiaz, Muhammad Abdurrahman Hamdin, Candra Dwipayana Hasina, Raisya Humaira, Ani Fatin Inggit, Baiq Putri Maharani Bine Lisnasari, Baiq Risky Wahyu Maghfirahandini, Reivirly Khairadaty Mahacita Andanalusia Mardiyah, Raudatul Ni Made Amelia Ratnata Dewi Nuralyza, Imasayu Nurhidayati Nurhidayati Ocktaviana Saputri, Legis Praditama, Lalu Denendra Pratama, Iman Surya Putri, Dhea Rizma Demula Putri, Dheden Nurhani Bija Rahmatullah, Lalu Mas’ud Salsabiella, Baiq Rani Saputra, Yoga Dwi Siti Fatmah, Siti Solehah, Kurnia Ulya, Tuhfatul Utari, Weny Syafitri Utari, Widi Gustita Vitri, Desy Aryanti Pardilla Yazid Maula