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All Journal Jurnal Riset Kefarmasian Indonesia Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Hayatus Sa'adah
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Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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FORMULASI ORALLY DISINTERGRATING TABLET (ODT) EKSTRAK ETANOL DAUN KEMANGI (Ocimum americanum L.) DENGAN VARIASI KONSENTRASI EXPLOTAB® Yulistia Budianti Soemarie; Hayatus Sa'adah; Tri Marginingsih
Jurnal Ilmiah Manuntung Vol 4 No 1 (2018): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v4i1.142

Abstract

Bad breath is usually caused by bacteria and leftovers in the mouth. Utilization of natural ingredients that can be used to overcome the problem of bad breath one of them by using basil leaves (Ocimum americanum L.), which has activity as an antibacterial. The development of the preparations was done on basil leaves to overcome bad breath is by formulating the basil leaves ethanol extract into the Orally Disintegrating Tablet (ODT) preparation. The purpose of this study was to investigate the effect of explotab® concentration variations on the physical properties of ODT and to determine the best of concentrations of Explotab® that fulfill the physical properties of ODT. The type of research conducted was an experimental study. Research object was basil leaves ethanol extract formulated into ODT with Explotab® 2% w/b, 4% w/w, 6% w/b and 8% w/w variation. Physical evaluations test then conducted including : the uniformity of weight evaluation, the hardness test, the friability test, and the dissolved time. The results showed that the explotab® concentration variations had an effect on the physical properties of tablets and the formula with the Explotab® 8% b/b concentration was the best formula that could produce the best ODT tablet with physical properties. Keywords : Basil leaves (Ocimum americanum L.), Explotab®, Orally Disintegrating Tablet (ODT)
FORMULASI DAN UJI PERTUMBUHAN RAMBUT KELINCI DARI SEDIAAN HAIR TONIC KOMBINASI EKSTRAK DAUN SELEDRI (Apium graveolens Linn) DAN DAUN MANGKOKAN (Polyscias scutellaria (Burm.f.) Fosberg) Siti Jubaidah; Ria Indriyani; Hayatus Sa'adah; Heri Wijaya
Jurnal Ilmiah Manuntung Vol 4 No 1 (2018): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v4i1.146

Abstract

Apium graveolens Linn and Polyscias scutellaria (Burm.f.) leaves are empirically widely used to stimulate hair growth. The purpose of this research is to combine celery leaf extract and mangkokan leaf extract formulated in hair tonic. The hair tonic preparations made were evaluated by performing a physical test of the preparation and knowing the best concentration of celery leaf extract and mangkokan leaf extract on rabbit hair growth. The hair tonic were prepared in 3 formulations with the ratio of Celery leaf extract and mangkokan leaf extract (5:5 ; 7,5:2,5 and 2.5:7,5)% w / v. The positive control used is hair tonic Minoxidil 2%. Physical tests of the preparation include organoleptic test, pH and viscosity test. Hair growth activity test is done by applying hair tonic on the 3 rabbits shaved hair and hair growth measurements until the 21st day. The data of hair growth measurements were tested statistically by ANOVA test method. Based on the research result, it can be concluded that hair tonic combination of celery leaf extract and mangkokan leaf extract with ratio (7.5: 2,5)%, has average hair length 2,459 cm and hair weight 0,199 g is the optimum concentration in stimulating hair growth activity with positive control has average hair length 2,493 cm and hair weight 0,285 g. Test statistically there was no significant difference between extract and positive control. Keywords : Apium graveolens Linn, Polyscias scutellaria (Burm.f.) Fosberg, hair tonic.
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL BIJI BUAH NYIRIH (Xylocarpus granatum) DENGAN METODE DPPH SECARA SPEKTROFOTOMETRI UV-VIS Achmad Kadri Ansyori; Mutmainna Tamrin; Hayatus Sa'adah
Jurnal Riset Kefarmasian Indonesia Vol. 6 No. 2 (2024): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v6i2.527

Abstract

   The nyirih plant (Xylocarpus granatum) is a type of mangrove that has been used for generations by coastal communities as traditional medicine. The flavonoid compounds contained in the nyirih plant are a group of polyphenols which have potential as antioxidants that can reduce free radicals. The aim of this research was to determine the antioxidant activity of ethanol extract of nyirih fruit seeds. The research carried out was non-experimental research, the stages of this research started from plant determination and sample collection, making simplicia, making extracts using the maceration method with 70% ethanol, phytochemical screening, and antioxidant activity testing using the DPPH method as free radicals which were measured using a spectrophotometer. UV-Vis. The research results obtained showed that the ethanol extract of nyirih fruit seeds positively contained secondary metabolites in the form of alkaloids, flavonoids, tannins and saponins. The results of the antioxidant activity test of the ethanol extract of nyirih fruit seeds obtained an IC50 value of 8.2729 ppm in the very strong antioxidant category.
Co-Authors Achmad Kadri Ansyori Heri Wijaya Mutmainna Tamrin Ria Indriyani Siti Jubaidah Tri Marginingsih Yulistia Budianti Soemarie