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All Journal Bioscientia Medicina : Journal of Biomedicine and Translational Research Open Access Indonesian Journal of Medical Reviews Bioscientia Medicina : Journal of Biomedicine and Translational Research JISE
Davin
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Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience

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Guava Leaf Extract: A Promising Alternative to Chlorhexidine for Reducing Streptococcus mutans Colonization on Orthodontic Appliances Davin; Firdha Muharraran; Weni Selvina
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 4 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i4.1252

Abstract

Background: Streptococcus mutans is a major contributor to the formation of dental plaque and the initiation of caries. Orthodontic appliances, particularly removable ones, can create favorable conditions for S. mutans colonization, increasing the risk of caries and other oral health issues. Chlorhexidine is a commonly used antimicrobial agent in dentistry, but it can have side effects like tooth staining and altered taste. Guava leaf extract has shown promising antibacterial properties due to its rich content of flavonoids, tannins, and other bioactive compounds. This study aimed to compare the effectiveness of guava leaf extract and chlorhexidine in reducing S. mutans colonization on acrylic-based removable orthodontic appliances. Methods: This in vitro study used 25 acrylic plates, which were divided into five groups: guava leaf extract at concentrations of 75%, 80%, and 90%, chlorhexidine gluconate 0.2% (positive control), and aquades (negative control). The acrylic plates were first contaminated with S. mutans and then immersed in the respective solutions for 10 minutes. The number of S. mutans colonies was then counted using a colony counter. Results: The mean number of S. mutans colonies was significantly lower in the chlorhexidine group (27.8 ± 6.6 CFU/ml) and the guava leaf extract groups (9.4 ± 3.3 CFU/ml for 90%, 42 ± 7.8 CFU/ml for 80%, and 381 ± 81.1 CFU/ml for 75%) compared to the aquades group (1461.2 ± 274.5 CFU/ml). There was no significant difference between the chlorhexidine group and the 90% and 80% guava leaf extract groups. Conclusion: Guava leaf extract, particularly at concentrations of 90% and 80%, is as effective as chlorhexidine in reducing S. mutans colonization on orthodontic appliances. Guava leaf extract may be a promising natural alternative to chlorhexidine for maintaining oral hygiene in orthodontic patients, especially those with concerns about chlorhexidine's side effects.
Implementation of the utilization of PT BNI (Persero) Tbk CSR funds at Raden Intan State Islamic University Lampung Davin
JOURNAL OF INTERDISCIPLINARY SCIENCE AND EDUCATION Vol 1 No 1 (2021): Journal of Interdisciplinary Science and Education
Publisher : STIES ALIFA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70371/jise.v1i1.6

Abstract

CSR is a company's concern for the interests of other parties more broadly, not just the interests of the company itself. For companies that consistently implement CSR in their activities, in the long term they will benefit in the form of trust from their stakeholders. The purpose of this study was to determine the implementation of the utilization of CSR funds of PT BNI (Persero) at Raden Intan State Islamic University, Lampung. The research method used in this study uses qualitative methods. The results of this study indicate that the implementation of the utilization of CSR funds of PT BNI (Persero) at UIN Raden Intan Lampung is quite good, namely the provision of pensions and allowances; education funds; contribute to improving the quality of life of the community and the environment.
Knowledge and Attitude Influence on Oral Hygiene Practices among University Dental Students with Fixed Orthodontic Appliances Davin; Maorina; Stevanus Daniel
Open Access Indonesian Journal of Medical Reviews Vol. 5 No. 2 (2025): Open Access Indonesian Journal of Medical Reviews
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/oaijmr.v5i2.707

Abstract

Fixed orthodontic appliances can complicate oral hygiene maintenance, increasing the risk of dental caries and periodontal diseases. This study aimed to assess the relationship between knowledge, attitude, and oral hygiene practices among university dental students undergoing fixed orthodontic treatment. A cross-sectional study was conducted among dental students at Universitas Prima Indonesia. Data were collected using a self-administered questionnaire that included questions on oral hygiene knowledge, attitude towards oral health, and oral hygiene practices. Descriptive statistics, Chi-square tests, and logistic regression were used to analyze the data. A total of 40 dental students participated in the study. The majority of the participants (95%) had good knowledge about oral hygiene. A positive correlation was found between knowledge and attitude (p=0.027), indicating that students with better knowledge exhibited more positive attitudes towards oral health. Furthermore, students with good knowledge were more likely to perform proper oral hygiene practices, including brushing twice daily (95%), using interdental brushes (97.5%), and visiting the dentist regularly (52.5%). In conclusion, this study highlights the importance of oral health knowledge and positive attitudes in promoting proper oral hygiene practices among dental students with fixed orthodontic appliances. Educational interventions aimed at improving knowledge and shaping attitudes may be beneficial in enhancing oral hygiene behavior and ensuring successful orthodontic treatment outcomes.
Guava Leaf Extract: A Promising Alternative to Chlorhexidine for Reducing Streptococcus mutans Colonization on Orthodontic Appliances Davin; Firdha Muharraran; Weni Selvina
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 4 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i4.1252

Abstract

Background: Streptococcus mutans is a major contributor to the formation of dental plaque and the initiation of caries. Orthodontic appliances, particularly removable ones, can create favorable conditions for S. mutans colonization, increasing the risk of caries and other oral health issues. Chlorhexidine is a commonly used antimicrobial agent in dentistry, but it can have side effects like tooth staining and altered taste. Guava leaf extract has shown promising antibacterial properties due to its rich content of flavonoids, tannins, and other bioactive compounds. This study aimed to compare the effectiveness of guava leaf extract and chlorhexidine in reducing S. mutans colonization on acrylic-based removable orthodontic appliances. Methods: This in vitro study used 25 acrylic plates, which were divided into five groups: guava leaf extract at concentrations of 75%, 80%, and 90%, chlorhexidine gluconate 0.2% (positive control), and aquades (negative control). The acrylic plates were first contaminated with S. mutans and then immersed in the respective solutions for 10 minutes. The number of S. mutans colonies was then counted using a colony counter. Results: The mean number of S. mutans colonies was significantly lower in the chlorhexidine group (27.8 ± 6.6 CFU/ml) and the guava leaf extract groups (9.4 ± 3.3 CFU/ml for 90%, 42 ± 7.8 CFU/ml for 80%, and 381 ± 81.1 CFU/ml for 75%) compared to the aquades group (1461.2 ± 274.5 CFU/ml). There was no significant difference between the chlorhexidine group and the 90% and 80% guava leaf extract groups. Conclusion: Guava leaf extract, particularly at concentrations of 90% and 80%, is as effective as chlorhexidine in reducing S. mutans colonization on orthodontic appliances. Guava leaf extract may be a promising natural alternative to chlorhexidine for maintaining oral hygiene in orthodontic patients, especially those with concerns about chlorhexidine's side effects.
Co-Authors Firdha Muharraran Maorina Stevanus Daniel Weni Selvina