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All Journal Indonesian Journal of Global Health research Deli Medical and Health Science Journal
Rachmasari, Novita
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Rosa Damascena Extract on Angiotensin-Converting Enzyme Activity in Wistar Rats Receiving Sodium Diet Rachmasari, Novita
Indonesian Journal of Global Health Research Vol 6 No S6 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6iS6.5329

Abstract

The prevalence of hypertension continues to rise in line with lifestyle changes. Often referred to as "the silent killer," hypertension can develop without warning. One of its contributing factors is excessive sodium intake, which disrupts the body's fluid balance regulated by the renin-angiotensin-aldosterone system. Elevated activity of the Angiotensin-Converting Enzyme within the Renin Angiotensin Aldosterone System mechanism can further lead to the development of hypertension. This study aims to investigate the impact of administering ethanol extract of Rosa damascena on the activity of Angiotensin-Converting Enzyme in Wistar rats fed a sodium-enriched diet. This experimental study utilized a post-test-only control group design. The subjects were 30 male Wistar rats, divided into five groups: 1) P0=control group; 2) P1=8% NaCl+RDEE 500mg/kgBW; 3) P2=0.35% NaCl+RDEE 500mg/kgBW; (4) P3=8% NaCl; and (5) P4=0.35% NaCl. The treatments were administered over 28 days. After the treatment period, the rats were anesthetized using a combination of Ketamine and Xylazine. The data were analyzed using a One-Way ANOVA test to assess differences among the treatment groups. A significant difference in Angiotensin-Converting Enzyme activity was observed in Wistar rats before receiving a sodium-enriched diet, with a p-value of <0.05. The ethanol extract of Rosa damascena was proven effective in reducing ACE activity in these rats, with a p-value of <0.05. The ethanol extract of Rosa damascena has demonstrated nephroprotective properties.
ANALISIS FAKTOR KINERJA PETUGAS KESEHATAN DI UNIT PELAYANAN TEKNIS RUMAH SAKIT KHUSUS MATA PROVINSI SUMATERA UTARA TAHUN 2022 Rachmasari, Novita; Andreas, Rusdi; Hadi, Milvan; Anwar, Khairil
Deli Medical and Health Science Journal Vol 1 No 2 (2024): Deli Medical And Health Science Journal (JDMHC)
Publisher : Fakultas Kedokteran, Institut Kesehatan Deli Husada Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jdmhc.v1i2.1819

Abstract

control of human assets is crucial in attaining desires. commonly, leaders assume excellent. health services will no longer run properly if the performance of the medical experts is not effective. The decline in the great of fitness offerings for eye sufferers apart from the overall performance factors of employees also can be influenced with the aid of other factors. This examine targets to decide the performance aspect analysis of health workers at UPT unique Eye sanatorium in North Sumatra Province. The populace in this have a look at had been all medical experts at UPT Eye unique health center, North Sumatra Province, particularly 148 humans with a total sample of 108 human beings. The sampling approach in this study changed into the consecutive sampling method, the information were analyzed the usage of the chi-square take a look at and logistic regression. based totally on the examine, it showed that there was a great courting between motivation, work discipline, rank magnificence, incentives, work skills, workload, tenure with the performance of medical examiners. The most dominant variable related to the overall performance of health workers is paintings area with a p-price of zero.00 where the cost of Exp (B) is 22.834 where health workers who have top work area 22 instances have appropriate performance in comparison to individuals who aren't disciplined. it's far was hoping that the clinic can pay extra interest to the performance of medical examiners such as motivation, incentives, cooperation, awards or praise for employees so one can enhance the overall performance of health workers in creating outstanding provider and assisting better paintings effects.
ANALISIS PERILAKU HIDUP BERSIH DAN SEHAT DENGAN KEJADIAN COVID-19 TAHUN 2022-20223 DI RUMAH SAKIT UMUM PUSAT H. ADAM MALIK Harahap, Mery Silvia; ., Irwandi; Rusli, Kevin; Hasian, Muhammad Tsawaby; Rachmasari, Novita; Sembiring, Rasman Gunadi; Sitorus, Friska Ernita; Rosa, Amelia
Deli Medical and Health Science Journal Vol 2 No 1 (2024): Deli Medical And Health Science Journal (JDMHC)
Publisher : Fakultas Kedokteran, Institut Kesehatan Deli Husada Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jdmhc.v2i1.2097

Abstract

Clean and healthy living behavior (PHBS) is a software established to improve health. for the reason that Covid-19 pandemic, the PHBS program, in particular hand washing with soap, has all started to be socialized on a large scale. therefore, analyzing the fundamental relationship between Covid-19 and one's behavior in dwelling easy and wholesome is crucial. This look at aimed to investigate clean and wholesome living behavior with the preval__ence of Covid-19 in 2022-2023 at H. Adam Malik valuable preferred medical institution.The kind of research used in this observe is quantitative with a Case-manage studies design. The sample on this observe have been patients who had and had never been wonderful for Covid-19 and have been treated at the H. Adam Malik principal trendy health facility in the range of 2022 - 2023, namely eighty human beings. records collection on this observe using a questionnaire. records have been analyzed quantitatively with univariate and bivariate eval__uation. most respondents in this have a look at were aged 26-35 years, male and woman respondents had the equal range, and the general public of respondents in this observe labored as non-medical examiners. The results confirmed that there has been a dating among the use of a mask, washing arms with soap, the use of a hand sanitizer, keeping distance, keeping off crowds, converting garments and bathing when you get home after traveling, consuming nutritious food, and physical pastime for at the least 30 minutes an afternoon, getting sufficient relaxation, masking your mouth when coughing, sneezing, along with your higher arm or tissue and then immediately throwing the tissue right into a closed trash can and straight away washing your fingers (ethics when sneezing and coughing) with the occurrence of Covid-19 with a p-price <zero.05.it is recommended to everybody, in particular health workers in hospitals, to continually practice easy and wholesome living behaviors (PHBS) in normal life, not handiest all through the Covid-19 pandemic.
Peran Hipertensi sebagai Faktor Risiko Terjadinya Gagal Ginjal Kronik Rachmasari, Novita; Asyraf, Mhd. Teguh
Deli Medical and Health Science Journal Vol 3 No 1 (2025): Deli Medical And Health Science Journal (JDMHC)
Publisher : Fakultas Kedokteran, Institut Kesehatan Deli Husada Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jdmhc.v3i1.2752

Abstract

The prevalence of chronic kidney disease continues to increase in Indonesia and ranks second after heart disease. Hypertension is one of the dominant factors causing chronic kidney disease. This study aims to analyze the relationship between hypertension and the risk of chronic kidney disease. The method used is a Systematic Literature Review (SLR) by reviewing articles from accredited national journals (SINTA) and international journals indexed in Scopus published between 2020 and 2025. The results of the analysis show that hypertension is significantly associated with the risk of chronic kidney disease. The underlying mechanism of hypertension and chronic kidney disease is through the activation of the renin-angiotensin-aldosterone system (RAAS).
Co-Authors Andreas, Rusdi Asyraf, Mhd. Teguh Hadi, Milvan Harahap, Mery Silvia Hasian, Muhammad Tsawaby Irwandi Irwandi Khairil Anwar Rosa, Amelia Rusli, Kevin Sembiring, Rasman Gunadi Sitorus, Friska Ernita