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All Journal Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan Praeparandi: Jurnal Farmasi dan Sains
Supardi Rifani Hutami
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Health Professions Medicine & Pharmacology Nursing Public Health

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Karakteristik Senyawa Kimia Ekstrak Ikan Gabus (Channa striata) dari Danau Tondano Menggunakan Fourier Transform Infra Red (FTIR) Sangkal Ahlan; Supardi Rifani Hutami
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 1 (2025): January: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i1.1056

Abstract

Snakehead fish (Channa striata) is a freshwater fish that is widely found in Indonesia. Snakehead fish has many benefits, including increasing albumin levels in the blood, increasing endurance, can heal wounds, both internal wounds, external wounds and post-operative wounds. The purpose of this study was to determine the character of the chemical compounds of snakehead fish extract in Lake Tondano. The method used for extraction is the Steaming method and analyzed using FTIR. The results of the study of Snakehead fish extract were analyzed in the FTIR computer application and obtained results showing 11 absorption band peaks. At the absorption band peaks of 3626.34 cm-1 and 3445.20 cm-1 indicate the O-H group suspected of having an alcohol compound. At the absorption band peak of 2097.19 cm-1 indicates the C = C group suspected of having an alkene compound. The peak of absorption band 1651.21 cm-1 and 1644.98 cm-1 indicates C=O group which is suspected to be amide compound I. The absorption band 1551.19 cm-1 indicates bending vibration of N-H group and stretching vibration of C-N which is suspected to be amide compound II. The absorption band 1458.33 cm-1 indicates CH3 group in the presence of collagen. The absorption band 1400.04 cm-1 indicates COO group which is suspected to be amino acid compound, aspartic acid and glutamic acid. The absorption band 1080.74 cm-1 indicates C-N group which is suspected to be amine compound. And the last absorption band is 562.15 cm-1 and 494.05 cm-1 indicates stretching vibration which indicates other compounds
Skrining Fitokimia dan Uji Kualitatif Aktivitas Antioksidan Ekstrak Etanol Daun Ketepeng Cina (Cassia Alata L) dengan Metode DPPH Husen Ernawati; Supardi Rifani Hutami; Mantali M. Fathurrachman
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 2 (2025): March: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i2.1068

Abstract

Cassia alata L or generally knowles as Chinese leaves contain phytochemical compounds, one of which is flavonoids which have the potential as antioxidants, antioxidants can be used to prevent diseases with oxidative stress. The purpose of this study was to determine the content of phytochemical screening and qualitative testing of antioxidant activity ethanol ekstract of Chinese leaves (Cassia alata L) using the DPPH method. This study is a qualitative study with an extraction process using the maceration method with 96% ethanol solvent. Phytochemical screening and antioxidant activity testing were carried out by adding specific reagents. The results of phytochemical screening and antioxidant activity testing of Chinese leaves (cassia alata L) ekstract contain bioactive compounds such as flavonoids, saponins, tannins and antioxidant activity testing with DPPH reagents showed that Chinese leaves (cassia alata L) extract has antioxidant activity which is indicated by a change of the color from purple to yellow. From the results obtained, it can be concluded that the flavonoid compound content in Chinese leaves (cassia alata L) extract can potentially act as an antioxidant.
SKRINING FITOKIMIA DAN UJI KUALITATIF AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAUN KELOR (Moringa oleifera Lam) DENGAN METODE KROMATOGRAFI LAPIS TIPIS (KLT) Siti Fatimah Azzahra Mahmud; Supardi Rifani Hutami; Chabibah A. Ike
Praeparandi : Jurnal Farmasi dan Sains Vol 9 No 1 (2025): Praeparandi : Jurnal Farmasi dan Sains
Publisher : Fakultas Farmasi Universitas YPIB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51997/r7x6dp75

Abstract

Indonesia memiliki keanekaragaman hayati tinggi, termasuk tanaman kelor (Moringa oleifera) yang dikenal sebagai obat tradisional. Penelitian ini bertujuan mengidentifikasi metabolit sekunder dan aktivitas antioksidan dari ekstrak etanol daun kelor. Metode yang digunakan meliputi maserasi dengan etanol 96%, skrining fitokimia, dan uji DPPH menggunakan KLT. Hasil menunjukkan ekstrak etanol daun kelor mengandung alkaloid, flavonoid, saponin, tanin, dan steroid, namun tidak terdeteksi terpenoid. Aktivitas antioksidan ditunjukkan dari perubahan warna pada plat KLT. Nilai Rf masing-masing 0,67 dan 0,8 di bawah sinar UV, dan rendemen ekstrak sebesar 5,698%, di bawah standar farmakope (≥10%). Kesimpulannya, daun kelor mengandung senyawa bioaktif yang berpotensi sebagai antioksidan alami.
Co-Authors Chabibah A. Ike Husen Ernawati Muhammad Fathurrachman Mantali Sangkal Ahlan Siti Fatimah Azzahra Mahmud