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All Journal Mengabdi: Jurnal Hasil Kegiatan Bersama Masyarakat Mikroba: Jurnal Ilmu Tanaman, Sains dan Teknologi Pertanian
Tiara Nabila Putri
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Agriculture, Biological Sciences & Forestry Humanities Computer Science & IT Education Health Professions Social Sciences

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Analisis Ekstrak Metanol Daun Sirsak (Annona Muricata Linn.) Terhadap Sel Kanker Prostat Tiara Nabila Putri; Ardi Mustakim
Mikroba : Jurnal Ilmu Tanaman, Sains Dan Teknologi Pertanian Vol. 2 No. 1 (2025): April : Mikroba : Jurnal Ilmu Tanaman, Sains Dan Teknologi Pertanian
Publisher : Asosiasi Riset Ilmu Tanaman Dan Hewani Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/mikroba.v2i1.255

Abstract

Soursop leaves contain active compounds annonaceous acetogenins which are known to have cytotoxic activity against cancer cells. This study aims to evaluate the effect of soursop leaf methanol extract (EMDS) on the viability and growth inhibition of PC3 prostate cancer cells. The research method used was an in vitro experiment with subjects in the form of PC3 cell lines divided into five groups, namely the cell control group, the treatment group with EMDS at concentrations of 6.25; 12.5; and 25 mg/mL, and the group given doxorubicin as a positive control. Cell viability was analyzed using the MTT assay method after incubation for 0 and 24 hours, and cell morphology was observed. Data analysis was carried out using the ANOVA test. The results showed that the EMDS group with concentrations of 6.25 and 12.5 µg/mL experienced a decrease in OD values, although statistically there was no significant difference. The concentration of 12.5 µg/mL had the highest inhibitory effect on cell viability with an OD value of 0.94. Observation of cell morphology indicates the presence of cytotoxic effects. Conclusion: methanol extract of soursop leaves has potential as an anticancer agent against PC3 prostate cancer cells, although the inhibitory effect is relatively small.
A Local Wisdom-Based Campus Bazaar as a Means of Public Service Education for Students Erinaldi Erinaldi; Muhalida Zia Ibhar; Sri Rahayu; Tiara Nabila Putri
MENGABDI : Jurnal Hasil Kegiatan Bersama Masyarakat Vol. 3 No. 2 (2025): April : MENGABDI : Jurnal Hasil Kegiatan Bersama Masyarakat
Publisher : Asosiasi Riset Ekonomi dan Akuntansi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/mengabdi.v3i2.2100

Abstract

This Community Service Program (PKM) is designed to enhance students' knowledge and practical skills in public service, while also promoting local economic empowerment through the organization of a campus bazaar that highlights local wisdom. Held at the Lancang Kuning Dumai College of Administrative Sciences, the program involved collaboration between lecturers, students, micro, small, and medium enterprises (MSMEs), and the wider community. Using a participatory approach, students played an active role in planning, implementing, and evaluating the bazaar, allowing them to apply theoretical knowledge in a real-world context. The program provided valuable hands-on experience in public service delivery, business management, and marketing, focusing on products derived from local traditions and culture. For local MSMEs, the bazaar served as an opportunity to increase product sales and expand their marketing reach, strengthening their presence in the community. The program successfully demonstrated the power of collaboration between educational institutions and local businesses in fostering economic development. By aligning academic activities with community needs, this initiative contributes to creating a sustainable local economy, emphasizing the importance of local wisdom in modern business practices.
Co-Authors Ardi Mustakim Erinaldi Erinaldi Muhalida Zia Ibhar SRI RAHAYU