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Le, Tien Xuan
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Chemical Engineering, Chemistry & Bioengineering Chemistry

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High Potential of Herbal Plant Extracts for Skin Protection from Ultraviolet Radiation Le, Tien Xuan; Dang, Phuong Yen; Tran, Uyen Khanh Nguyen; Nguyen, Nhu Quynh Trung; Tran, Thanh Truc
Indonesian Journal of Chemistry Vol 25, No 1 (2025)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.99167

Abstract

This research is dedicated to exploring the photoprotective qualities of extracts from 10 different herbal plants to identify natural ultraviolet (UV) filtering agents suitable for use in cosmetics. The study pinpointed specific plant parts that showed promising photoprotective capabilities, including the fruits of Gardenia jasminoides L., the flowers of Chrysanthemum morifolium Ramat., as well as the leaves of Camellia sinensis L. and Moringa oleifera L. Among these, G. jasminoides extracts stood out for their superior photoprotection. Specifically, G. jasminoides led with an impressive in vitro SPF of 40.8 ± 0.2, with C. morifolium, C. sinensis, and M. oleifera trailing closely. Hence, the extracts were added to the base of the lotion cream to evaluate the stability and photoprotective activity. Additionally, even though natural extracts cannot completely replace conventional UV filters, they have substantially decreased the reliance on physical or chemical UV filters. Thus, this study provides a strong foundation for natural antioxidants' status and potential use for UV filtration.                                                                                                    
Enriching 1,8-Cineole Content in Eucalyptus camaldulensis D. Raw Essential Oil: An Investigation on Optimizing Vacuum Fractional Distillation Process Le, Tien Xuan; Nguyen, Minh Nhat; Le, Trung Minh; Pham, Minh Chau Vu
Indonesian Journal of Chemistry Vol 25, No 2 (2025)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.99211

Abstract

This study addressed the gap in optimizing the 1,8-cineole content in Eucalyptus camaldulensis essential oil, an area with a limited focus in existing literature. While previous research has explored distillation methods for essential oils, this study is the first to systematically investigate the effects of key operational parameters on cineole enhancement using batch vacuum fractional distillation. The optimization process was carried out using a single–factor method focusing on operating pressures (60, 80, 100, 120, 140, and 160 mmHg), column types (Vigreux and Hempel), packing materials (wire mesh, large strings, small strings), and column heights (300, 400, 500, and 600 mm). After each distillation experiment, the essential oil samples were analyzed using GC-MS to quantify the concentration of 1,8-cineole and other components. The best result, achieved at 60 mmHg with a 500 mm Hempel column packed with small metal helixes (2 × 10 mm), increased 1,8-cineole content from 47.9% to 74.6%, with 97% recovery and over 60% yield. These findings highlight the impact of distillation parameters on cineole concentration, marking a 1.5-fold improvement. This optimized distillation process offers an efficient alternative for producing high-bioactivity cineole oil, with potential pharmaceutical and personal care applications, reducing reliance on complex synthesis.
Co-Authors Dang, Phuong Yen Le, Trung Minh Nguyen, Minh Nhat Nguyen, Nhu Quynh Trung Pham, Minh Chau Vu Tran, Thanh Truc Tran, Uyen Khanh Nguyen