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All Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Akademika Kimia
Baharuddin Hamzah
Tadulako University
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Materials Science & Nanotechnology Physics

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The Effectiveness of Bougainvillea (Bougainvillea spectabilis willd) Extract on Reducing Blood Glucose in Hypercholesterolaemia White Rats Muhammad Fakhrul Hardani; Baharuddin Hamzah; Ririen Hardani; Magfirah; Sitti Rahmawati; Purnama Ningsih
Jurnal Penelitian Pendidikan IPA Vol 11 No 1 (2025): January
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i1.9762

Abstract

Bougainvillea leaves are often used by the public as a treatment by drinking boiled water, but their use as a blood sugar-lowering agent is not supported by scientific data. The purpose of this study was to determine the effect of reducing blood glucose levels and to determine the dose of extract that is effective in in white rats. The plant's herbal extract was prepared using the reflux method with 90% ethanol solvent. This study uses a laboratory experimental method to compare blood glucose levels in white rats before and after administration of herb extract at doses of 100, 200, and 300 mg/kg BW orally using high-fat feed induction and streptozotocin. Blood glucose levels were measured using a glucometer, and mice were declared positive for diabetes with fasting blood sugar levels above 126 mg/dL. The number of test animals used in this study was 30 mice, divided into 6 groups. A randomized block design was used as the research design. The study's findings revealed that administering Bougainville spectabilis willd herb extract at doses of 100, 200, and 300 mg/kg BW can reduce blood glucose in test animals with an effective dose of 200 mg/kg BW
Determination of Tanin Extract of Belimbing Wuluh Leaves (Averrhoa Bilimbi L.) by Uv-Vis Spectroscopy Methods Ririen Hardani; Muhammad F. Hardani; Baharuddin Hamzah; Sindy T. Tamala
Jurnal Akademika Kimia Vol. 14 No. 3 (2025)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24775185.2025.v14.i3.pp138-143

Abstract

Wuluh star fruit plant (Averrhoa bilimbi L.) was a traditional medicinal plant that was rarely utilized as a natural medicine and contained many secondary metabolite compounds, one of which was tannin. This study aimed to determine the type of tannin and the amount of tannin content in belimbing wuluh leaves. Wuluh star fruit leaf powder was extracted by the maceration method using 96 % ethanol solvent, and then the filtrate was concentrated by rotary evaporator. Identification of tannin types in the extract was performed using CH3COOH 10 %, (Pb(CH3COO)2) 10 %, HCl, FeCl3, and KBr. For analysis of tannin content, Folin-Ciocalteau reagent and 15 % Na2CO3 solution were added, and then analyzed using UV-Vis spectrophotometry at a wavelength of 765 nm. The results of the identification of tannin types showed that belimbing wuluh leaves included condensed tannins, and the results of the analysis showed that the tannin content was 7.282 mg/g extract.
Determination of Total Flavonoid Content in Local Sakura Leaf Extract or Small Bungur (Lagerstroemia indica L.) Nur S. Damayanti; Sri H. V. Pulukadang; Sitti Aminah; Baharuddin Hamzah; Reny Reny
Jurnal Akademika Kimia Vol. 14 No. 3 (2025)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24775185.2025.v14.i3.pp151-156

Abstract

The small bungur plant (Lagerstroemia indica L.) is one of the plants with potential as a medicinal plant. Almost all parts of this plant can be used, namely the leaves, stems, fruit and roots. Bungur leaves can be used for skin diseases, leaf powder for malaria, and decoction of old leaves for diabetes. Bungur leaves contain chemical compounds, one of which is flavonoids. This study aims to determine the total flavonoid content of extracts from young and old leaves of local cherry blossoms (small bungur), using UV-Vis spectrophotometry. The extraction method used was multistage maceration using three different solvents: hexane (nonpolar), ethyl acetate (semipolar), and methanol (polar). The results showed that the average total flavonoid content of young leaf extracts and old leaves of small bungur, measured by UV-Vis spectrophotometry at a maximum wavelength of 410 nm, was 8.810 mg/100g and 7.301 mg/100g, respectively. Among the three solvents used, extracts of young and old leaves of small bungur using hexane and ethyl acetate do not contain flavonoids, whereas extracts of young and old leaves of small bungur using methanol do.
Co-Authors Magfirah Muhammad F. Hardani Muhammad Fakhrul Hardani Nur S. Damayanti Purnama Ningsih Reny Reny Ririen Hardani Sindy T. Tamala Sitti Aminah Sitti Rahmawati Sri H. V. Pulukadang