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All Journal Medula Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan
Swastini, Ni Putu
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Education Health Professions Medicine & Pharmacology Neuroscience Public Health

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One-bottle drainage system in Tuberculosis-Associated Secondary Spontaneous Pneumothorax: A Case Report : Gede Ardi Saputra; Pratama, Muhammad Reqza; Munthe, Eva Lydia; Swastini, Ni Putu
Medula Vol 14 No 9 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i9.1190

Abstract

Tuberculosis (TB) is one of the ten leading causes of death in the world. Indonesia ranks second in the world in terms of TB cases and is the largest contributor to the increase in new cases. This study reports a man suffering from TB with a rare complication, secondary spontaneous pneumothorax. We describe a 27-year-old male smoker who reported sudden shortness of breath two hours ago, accompanied by pain in the left side of the chest when breathing. He is currently undergoing advanced antituberculosis treatment. A physical examination and chest X-ray revealed spontaneous pneumothorax. A GeneXpert sputum test 2 months ago was positive for Mycobacterium tuberculosis. We performed chest tube placement. After 19 days, the patient showed clinical improvement and responded well to treatment. In conclusion, secondary spontaneous pneumothorax (SSP) in tuberculosis patients is a rare occurrence. The patient received chest tube placement, as well as oxygen therapy, anti-TB drugs, and chest physiotherapy. We treated the individual using a one-bottle system because this type of pneumothorax is simple, practical, and easy for mobile individuals.
Efficacy and Safety of Pravastatin in Placental-Related Disorders: Systematic Review And Meta-Analysis Of Randomized Controlled Trials: english Saputra, Gede Ardi; Pandiangan, Asri; Suryatman, Muhammad Villiandy; Swastini, Ni Putu
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 19 No 1 (2025): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan (In Press)
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Placental-related disorders impact over 33% of pregnancies. Several of these syndromes lead to higher rates of maternal and fetal death and morbidity and can have long-term health consequences. Several RCTs have found that pravastatin is associated with a significant reduction in the incidence of preterm preeclampsia and preterm birth. However, alternatives require substantial evidence. On the methods, two writers assessed the risk of bias. The Cochran test was used to assess heterogeneity among studies. The Mantel-Haenszel technique was used to obtain the results. The study's results were described using forest plots. The study used six randomized controlled trials. Findings showed a reduced risk of preeclampsia, preterm birth, and NICU admission in pregnant women taking pravastatin. There was no significant reduction in the risk of neonatal respiratory distress, congenital disorders, and adverse events of headache, heartburn, and musculoskeletal pain. Our conclusion, this study suggests that pravastatin use may have beneficial effects in reducing the risk of placental-related disorders in patients.
Co-Authors Gede Ardi Saputra Munthe, Eva Lydia Pandiangan, Asri Pratama, Muhammad Reqza Saputra, Gede Ardi Suryatman, Muhammad Villiandy