Article History Submitted, Accepted, Published, Continuity of care (CoC) is a service that is achieved when there is an ongoing relationship between a woman and a midwife. Continuing care relates to the quality of service over time which requires a continuous relationship between patients and health professionals. Obstetric services should be provided from preconception, early pregnancy, during all trimesters, birth and delivery up to the first six weeks postpartum which can reduce numbers Maternal and infant mortality affects the health status of a nation. The aim of providing comprehensive midwifery care to Mrs E (Continuity of Care) includes pregnancy, labor, postpartum, newborns and neonates up to family planning. In this research method, the author used a data collection method, namely using interviews, observation with primary and secondary data through the KIA Book, physical examination and this research began in February - August2024, the research instrument used SOAP. Based on the results of a comprehensive case study (Continuity of Care) on Mrs E from pregnancy, labor, postpartum, newborns and neonates, it was found that Mrs. E, 30 years old, G2P1A0, 39 weeks of gestation, no problems were found, gave birth to Mrs. E was carried out at Puri Asih General Hospital. The postpartum period was normal, there was no bleeding, uterine contractions were good, lochea rubra, perineal abrasions, the mother received vitamin A. In the newborn the results of the anthropometric examination were normal. Mrs. E decided to use contraceptive injections for 3 months. Abstrak Continuity of care (CoC) adalah pelayanan yang dicapai ketika terjalin hubungan yang terus-menerus antara seorang wanita dan bidan. Asuhan yang berkelanjutan berkaitan dengan kualitas pelayanan dari waktu kewaktu yang membutuhkan hubungan terus menerus antara pasien dengan tenaga profesional kesehatan. Layanan kebidanan harus disediakan mulai prakonsepsi, awal kehamilan, selama semua trimester, kelahiran dan melahirkan sampai enam mingggu pertama postpartum yang dapat menurunkan Angka Kematian Ibu dan bayi untuk derajat kesehatan suatu bangsa. Tujuan memberikan asuhan kebidanan Pada Ny E secara Komperehensif (Continuity Of Care) meliputi masa kehamilan, masa persalinan, nifas, bayi baru lahir dan neonatus sampai KB. Metode dalam penelitian ini penulis menggunakan metode pengumpulan data yaitu menggunakan wawancara, observasi dengan data primer dan sekunder melalui Buku KIA, pemeriksaan fisik serta penelitian ini dimulai sejak bulan Februari – Agustus 2024 instrumen penelitian menggunakan SOAP. Berdasarkan hasil studi kasus secara Komperehensif (Continuity Of Care) pada Ny E dari kehamilan, masa persalinan, nifas, bayi baru lahir dan neonatus didapatkan Ny. E usia 30 Tahun G2P1A0 usia kehamilan 39 minggu tidak ditemukan masalah, Persalinan pada Ny. E dilakukan di Rumah Sakit Umum Puri Asih. Masa nifas berlangsung normal tidak ada pendarahan, kontraksi uterus baik, lochea rubra, luka lecet perinium, ibu mendapatkan vitamin A. Pada bayi baru lahir hasil pemeriksaan antropometri normal. Ny. E memutuskan menggunakan KB Suntik 3 bulan.