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All Journal International Journal of Evaluation and Research in Education (IJERE) The Indonesian Biomedical Journal
Fauzee, Mohd Sofian Omar
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Biochemistry, Genetics & Molecular Biology Education Public Health

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Unveiling the role of organizational commitment on job satisfaction and job performance in Islamic education Yaakob, Mohd Faiz Mohd; Habibi, Akhmad; Halili, Siti Hajar; Abdullah, Hamdy; Yaqin, Lalu Nurul; Alqahtani, Turki Mesfer; Fauzee, Mohd Sofian Omar
International Journal of Evaluation and Research in Education (IJERE) Vol 14, No 2: April 2025
Publisher : Institute of Advanced Engineering and Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijere.v14i2.31071

Abstract

This study evaluates the influences of organizational commitment components on job satisfaction and job performance among Islamic boarding school (IBS) teachers. It also aimed to decide the mediating effect of job satisfaction on the relationship between organizational commitment and job performance. This comparative study compares the path coefficient between exogenous and endogenous constructs based on respondents’ countries, Malaysia and Indonesia. Through a simple random sampling, the data were gathered from 247 respondents. The analysis was conducted through partial least square structural equation modeling (PLS-SEM) approaches (measurement model, structural model, and multi-group analysis). The measurement model informed that the obtained data was valid and reliable. The structural model examination reports that normative and continuance commitment strongly predict job satisfaction. Similarly, continuance commitment and job satisfaction are significant predictors of job performance. As a mediator, job satisfaction successfully mediates the relationships between continuance commitment and job performance and between normative commitment and job performance. No significant differences emerge from the multi-group analysis results between IBS teachers from Kedah (Malaysia) and Jambi (Indonesia), regarding all direct paths between the constructs. This article provides knowledge contributions from Indonesia and Malaysia, in the context of Islamic education.
Luteolin Suppresses Endothelial Permeability and Nitric Oxide Scavenging Effects Yoong, Wong Theen; Choong, Shuit Siew; Fauzee, Mohd Sofian Omar; Ahmad, Zuraini; Hakim, Muhammad Nazrul
The Indonesian Biomedical Journal Vol 16, No 5 (2024)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v16i5.3198

Abstract

BACKGROUND: Numerous inflammatory diseases are linked to increased endothelial permeability through the nitric oxide (NO) flux in endothelial cells. Luteolin has in vitro and in vivo anti-inflammatory properties and has been reported to reduce endothelial permeability. However, the exact mechanism/s are yet to be determined. Thus, the present study was conducted to investigate the effects of luteolin in reducing endothelial permeability in vitro using bradykinin (BK) or sodium nitroprusside (SNP) through the NO pathway and the NO radical scavenging property of luteolin.METHODS: Human umbilical vein endothelial cells (HUVECs) in the treatment groups were dosed with luteolin at 5, 10, and 25 µM concentrations and allowed to incubate for one hour prior to induction. The L-NAME or HOE 140 were administered prior to the induction of BK or SNP in HUVECs. The NO radical scavenging test, the nitrite determination assay using L-NAME as antagonist, and the in vitro vascular permeability testing using HOE 140 as antagonist were performed.RESULTS: Endothelial permeability was decreased dose-dependently by 5, 10, and 25 µM luteolin in vitro via lowering NO generation. In comparison to HOE 140, luteolin suppressed the enhanced endothelial permeability more effectively. The suppression was 98.02% by 25 µM luteolin compared to HOE 140 94.05%. It was also discovered that luteolin, when incubated with SNP in a dose-dependent manner, possessed potent NO radical scavenging activities.CONCLUSION: The current data demonstrated luteolin's ability to scavenge NO radicals and significantly decrease endothelial permeability through the NO route. Thus, in complementary medicine, luteolin might be potential to improve endothelial permeability suppressor in reducing inflammation.KEYWORDS: luteolin, endothelial permeability, NO, scavenging property, HUVECs
Co-Authors Abdullah, Hamdy Ahmad, Zuraini Akhmad Habibi, Akhmad Alqahtani, Turki Mesfer Choong, Shuit Siew Hakim, Muhammad Nazrul HALILI, SITI HAJAR YAAKOB, MOHD FAIZ MOHD Yaqin, Lalu Nurul Yoong, Wong Theen