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All Journal CoMPHI Journal : Community Medicine and Public Health of Indonesia Journal Hang Tuah Medical Journal The International Journal of Medical Science and Health Research Journal of Tropical Pharmacy and Chemistry Surabaya Biomedical Journal
Retno Wisanti
Universitas Hang Tuah Surabaya
Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Pediatric Covid-19 Patients Laboratory Characteristics in Dr.Ramelan Central Navy Hospital: A-Year Epidemiology Study RETNO WISANTI; RUSDIAN NIATI NINGSIH
HANG TUAH MEDICAL JOURNAL Vol 20 No 1 (2022): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v20i1.326

Abstract

Covid-19 in children has several different characteristics with the adults, from clinical manifestation to laboratory result. There is also challenges in Covid-19 diagnosis in children with their inability to describe their condition clearly. Laboratory examination used to confirm the diagnosis, but the accuracy still in doubt. We aims to describe the laboratory examination result of pediatric Covid-19 patients. We analyze the medical records of 69 children with suspect Covid-19 who hospitalized in isolation room in a year period, from May 2020 to April 2021. All of the suspect patient were examined by PCR test, rapid antibody test, chest x-ray, and complete blood count. 40 patients were Covid-19 positively-confirmed by the PCR test. Chest x-ray gave better sensitivity and specificity for early screening than rapid antibody test. The complete blood count gave normal results in general, only slight relative lymphocytosis occurred. The neutrophilia and lymphopenia pattern in adults with Covid-19 are different with the children’s result. The increase of NLR, who commonly used as an early screening test in adult Covid-19, cannot be used in children. The lower inflammatory response and physiologically higher lymphocyte cell count in younger age explain these results. In conclusion, the laboratory test should be performed for pediatric Covid-19 cases, but not for confirm the diagnosis.
Studi Efek Samping Obat pada Pasien Neonatus yang Menjalani Rawat Inap Di Rumah Sakit Angkatan Laut Dr. Ramelan Surabaya Victoria Yulita Fitriani; Widyati Widyati; Azis Huibeis; Retno Wisanti
Journal of Tropical Pharmacy and Chemistry Vol. 1 No. 1 (2010): J. Trop. Pharm. Chem.
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jtpc.v1i1.11

Abstract

ABSTRACT Rational drug treatments to avoid adverse drug reactions in neonates are depend on physiologic immaturity and age-related changes in pharmacokinetic and pharmacodynamic factor. This condition lead neonates more prone to adverse drug reaction than adults.The aim of this study was to estimate the prevalence of adverse drug reactions that occured at Dr. Ramelan Navy Hospital's NICU observed in November 26th 2007 to January 26th 2008. It was also to analyze kind of medication that caused adverse drug reactions.The study employed 94 patients (5 premature neonates and 89 term neonates) who were observed perspectively from November 26th 2007 to January 26th 2008. Demographic data, drug therapy, relevant medical histories, laboratory data were recorded in this study. The study result was assessed by literature study. The study result were analysed with Descriptive analysis. The most common adverse drug reaction occurred in this population was potential adverse drug reaction (99.5%). The most adverse drug reaction generated from this study was come from the use of ampicillin sulbactam (42.7%), gentamisin (31.4%), ceftriaxone (16.2 %), amikacin (7.6 %), aminofilin (1.1 %), ampicillin (0.5 %), and dexamethasone (0.5 %). The study showed that almost all of adverse drug reaction occurred in this study was potential adverse drug reaction (99.5%). Keywords: neonates; adverse drug reactions; NICU ABSTRAK Terapi obat yang rasional untuk menghindari efek samping dari obat pada neonatus bergantung pada ketidakmatangan fisiologik dan perubahan faktor farmakokinetika dan farmakodinamika yang terkait usia. Kondisi ini membawa neonatus lebih mudah terpapar efek samping obat daripada orang dewasa. Tujuan dari penelitian ini adalah untuk memperkirakan angka kejadian efek samping obat yang terjadi di NICU Rumah Sakit Angkatan Laut Dr. Ramelan Surabaya diamati secara prospektif sejak 26 November 2007 hingga 26 Januari 2008. Penelitian ini juga menganalisa jenis obat yang menyebabkan efek samping obat. Penelitian ini melibatkan 94 pasien (5 neonatus premature dan 89 neonatus term) yang diamati secara prospektif sejak 26 November 2007 hingga 26 Januari 2008. Penelitian ini mencatat data demografi, terapi obat, sejarah penyakit yang terkait, dan data laboratorium. Data tersebut dianalisa melalui studi literatur. Hasil penelitian dianalisa dengan menggunakan analisis deskriptif. Efek samping obat yang sering muncul pada penelitian ini adalah efek samping potensial (99.5%). Efek samping yang terjadi pada penelitian ini terjadi akibat penggunaan ampisilin sulbaktam (42.7%), gentamisin (31.4%), ceftriaxon (16.2%), amikasin (7.6%), aminofilin (1.1%), ampisilin (0.5%), dan deksametason (0.5%). Penelitian ini menunjukkan bahwa sebagian besar efek samping obat yang terjadi pada penelitian ini adalah efek samping obat potensial. Kata kunci: neonatus; efek samping obat; NICU
Tuberculous Spondylitis : A Case Report Stefany Palyama; Retno Wisanti; Rusdian Niati Ningsih
The International Journal of Medical Science and Health Research Vol. 10 No. 3 (2025): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/07cbk506

Abstract

Objective: Tuberculous spondylitis is an infection of the spine caused by the Mycobacterium tuberculosis , is one of the most common infections. The WHO reports that 10.6 million TB cases are worldwide by 2022. By 2022, TB is the disease that causes the most deaths, with 1.3 million per year. Spondylitis Tuberculosis was extra pulmonary TB. The symptoms are fever, sweating especially at night, weight loss and loss of appetite, and palpable mass on the back. The sass can lead to permanent neurological deficits. The early identification and treatment is very important to avoid permanent damage in the future. Case: A 4 years old female patient with complaints of disappearing pain in the back since 10 days. A fever that has persisted for ten days and sweating at night. The patient's weight also decreased by 6kg. Immunization history is incomplete. There are no BCG vaccines. Her uncle had TB from 2018 and her neighbors too. Impression nutritional status was undernourished. Enlargement of the lymph in the neck area, and rhonci sounds in both fields of the lung were observed during the physical examination of the thorax. Tuberculin test showed induration 10mm. There was fixed palpable mass at the back, hard, no fluctuations, no rebound tenderness. Lumbosacral examination without contrast revealed a mass between vertebrathoracal ( VTh ) 4-9, it showed cold abscess. Lumbosacral MRI revealed compression anterior of the veterbralthoracal corpus ( VTh ) 7, and pushing to the spinal cord posteriorly, and showed gybus formation, and abscess on the anterior of veterbralthoracal ( VTh 4-7). Based on the patient's medical history, physical examination, laboratory, the patient was diagnosed with TB spondylitis. The patient underwent spinal stabilization and decompression, in addition to receiving OAT treatment. Conclusion: TB spondylitis is a rare case in children, but it is common in children with primary TB infection. Systemic and neurological symptoms can be found in patients with TB Spondylitis . The prognosis of TB Spondylitis is influenced by the age of the patient, the severity of bone deformity, the number of spinal bone involvement, and the patient's health history such as immunization status, nutritional status, and other accompanying diseases.
Bilateral Mumps with Orchitis : A Case Report Stefany Palyama; Retno Wisanti; Esthy Peospitaningtyas; Rusdian Niati Ningsih
The International Journal of Medical Science and Health Research Vol. 10 No. 3 (2025): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/3aeqvz04

Abstract

Background: Mumps or epidemic parotitis is an acute disease that often occurs in the salivary glands caused by infection from paramyxovirus . This virus spreads easily through airborne droplets and saliva. In the world, the incidence of mumps is 500,000 cases each year. Incomplete basic vaccination is one of the risk factors for mumps. Case Description: An 11-year-old male patient came with complaints of swelling in the right and left parotid glands. Initially the swelling was on the left. The patient had never been like this before. The patient's basic immunization history was incomplete. From physical examination, enlargement of both salivary glands was found. 2 weeks earlier at the patient's school, there were several students who experienced the same thing. The patient was referred to dr. Ramelan Central Naval Hospital after 5 days of hospitalization at the previous hospital and experienced swelling in the left scrotum. Discussion: Mumps often occurs in children aged 2-12 years. The occurrence of mumps can be caused by infection with the paramyxovirus virus which spreads from airborne droplets and salivary glands. One of the complications of mumps that often occurs in children is orchitis . Providing basic vaccines to children is one effort to prevent mumps. Bed rest, adequate fluid intake, and intravenous administration of NSAIDs and antibiotics can be options for mumps therapy. Conclusion: In this case, Mumps with Orchitis complications were diagnosed based on anamnesis, physical examination, and laboratory examination. Management of mumps is symptomatic. Incomplete basic vaccination is one of the biggest factors in the occurrence of mumps.
Pengaruh Fortifikasi Besi pada Makanan dalam Tatalaksana Anemia Defisiensi Besi pada Anak Ahmad Iqbal Romdloni; Adinda Rizka Ramadhini; Abdillah Maulana Satrioaji; Adil Abdullah; Agam Febbrian Syam; Retno Wisanti
Surabaya Biomedical Journal Vol. 4 No. 3 (2025): May
Publisher : Fakultas Kedokteran, Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/v4i3.151

Abstract

Tujuan Penelitian: Defisiensi besi adalah masalah nutrisi paling banyak di seluruh dunia melampaui malnutrisi energi protein. Anemia defisiensi besi pada anak berdampak negatif terhadap pertumbuhan, perkembangan kognitif, akademik, dan imunitas. Di seluruh dunia, tercatat 273 juta anak kurang dari 5 tahun menderita anemia dengan 60% di antaranya dikarenakan defisiensi besi. Fortifikasi besi disebut sebagai pendekatan preventif terbaik untuk mencegah anemia defisiensi besi. Meskipun demikian, pengetahuan terkait fortifikasi besi di Indonesia masih rendah. Penelitian ini bertujuan untuk mengetahui pengaruh fortifikasi besi pada makanan dalam tatalaksana anemia defisiensi besi pada anak. Metode Penelitian: Penelitian ini menggunakan metode studi literatur dengan sampel berupa 16 artikel pada jurnal internasional yang terindeks SCIMAGO dengan tahun publikasi 2019 hingga 2024. Artikel pada studi literatur ini diambil melalui Mendeley, Google Scholar, ScienceDirect, dan PubMed. Hasil: Fortifikasi besi berperan dalam menurunkan angka kejadian anemia defisiensi besi pada anak. Fortifikasi besi berguna sebagai upaya preventif dan terapi adjuvan terhadap suplementasi besi oral atau parenteral. Peran fortifikasi besi diperkuat dengan penambahan vitamin A, vitamin C, dan antihelmintik dalam regimen suplementasi besi. Kesimpulan: Fortifikasi besi pada makanan berpengaruh positif dalam tatalaksana anemia defisiensi besi pada anak.
Breaking The Cycle: Maternal Knowledge, Sanitation, dan Diarrhea Prevention in Toddlers widya fadhilascha; Danny Wresniwira Danandjaja; Ronald Pratama Adiwinoto; Retno Wisanti
CoMPHI Journal: Community Medicine and Public Health of Indonesia Journal Vol. 6 No. 3 (2026): Februari
Publisher : Perhimpunan Dokter Kedokteran Komunitas dan Kesehatan Masyarakat Indonesia (PDK3MI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37148/comphijournal.v6i3.326

Abstract

This research aims to explore the relationship between maternal knowledge and sanitation hygiene with the incidence of diarrhea in young children within the Socah Community Health Center's service area. The study employs a quantitative approach with an observational cross-sectional design. Primary data was gathered using a questionnaire assessing maternal knowledge and daily sanitation hygiene practices. Data analysis was conducted using both univariate and bivariate methods, including the chi-square test. The findings reveal that, among 101 mothers with toddlers who met the inclusion criteria, most had low knowledge (40.6%) and moderately implemented hygiene and sanitation practices (37.6%). Additionally, 47.5% of the children had experienced diarrhea in the past two weeks. The chi-square test showed a significant correlation between maternal knowledge and the occurrence of diarrhea (p < 0.001), as well as between hygiene and sanitation practices and the incidence of diarrhea in children (p < 0.001). The study concludes that both maternal knowledge and sanitation hygiene significantly affect the occurrence of diarrhea in children in the Socah Community Health Center area. It is recommended that health education regarding diarrhea prevention, personal hygiene, and environmental sanitation be enhanced to reduce diarrhea rates among infants. This research is intended to serve as a foundation for the planning of health support and prevention programs in the Community Health Center's service area.
Co-Authors Abdillah Maulana Satrioaji Adil Abdullah Adinda Rizka Ramadhini Agam Febbrian Syam Ahmad Iqbal Romdloni Azis Huibeis Danny W. Danandjaja Esthy Peospitaningtyas Ronald Pratama Adiwinoto Rusdian Niati Ningsih RUSDIAN NIATI NINGSIH Stefany Palyama VICTORIA YULITA FITRIANI widya fadhilascha Widyati Widyati