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All Journal Manuju : Malahayati Nursing Journal Indonesian Journal of Global Health research
Putra, Gian Dwi
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Education Health Professions Languange, Linguistic, Communication & Media Nursing Public Health

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Hubungan Depresi dengan Fatigue pada Pasien Kanker yang Menjalani Radioterapi Putri, Hadeci Lovenda; Putra, Gian Dwi
Malahayati Nursing Journal Vol 7, No 3 (2025): Volume 7 Nomor 3 (2025)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v7i3.19389

Abstract

ABSTRACT Approximately 10.9 million people are diagnosed with cancer globally each year, with many requiring radiotherapy as part of their treatment. A significant concern is that nearly 80% of cancer patients undergoing radiotherapy experience fatigue, which can interfere with daily activities and adversely affect their long-term quality of life. This study aims to determine the relationship between depression and fatigue in cancer patients undergoing radiotherapy. A correlational analytic research design with a cross-sectional approach was employed. The population included all cancer patients undergoing radiotherapy at Andalas University Hospital in 2024, and a sample of 130 patients was selected using the Purposive Sampling method. The research utilized two primary instruments: the Brief Fatigue Inventory (BFI) and the Depression Anxiety Stress Scale (DASS). Two enumerators were involved in the data collection process, ensuring consistency in perceptions. The collected data were processed using SPSS, and the analysis was conducted using the Kruskal Wallis test. The results indicated a significant relationship between depression and fatigue (p < 0.05). Most patients reported moderate fatigue, which was exacerbated by moderate levels of depression. This suggests that fatigue is influenced by the interplay between the physical effects of radiotherapy and the psychological conditions that significantly affect patients' quality of life. Keywords: Cancer, Depression, Fatigue, Radiotherapy  ABSTRAK Sekitar 10,9 juta orang seluruh dunia didiagnosis menderita kanker setiap tahunnya, sebagian di antaranya membutuhkan radioterapi sebagai bagian dari pengobatan. Namun, hampir semua pasien kanker (80%) yang menjalani radioterapi mengalami fatigue, yang dapat menggangu aktivitas sehari-hari memengaruhi kualitas hidup pasien dalam waktu yang panjang. Penelitian ini bertujuan untuk mengetahui hubungan depresi dengan fatigue pada pasien kanker yang menjalani radioterapi. Jenis penelitian yang digunakan analitik korelatif dengan pendekatan cross-sectional. Populasi dalam penelitian ini mencakup semua pasien kanker yang menjalani radioterapi di Rumah Sakit Universitas Andalas Tahun 2024. Sampel terdiri dari 130 pasien kanker yang menjalani radioterapi dan dipilih melalui Purposive Sampling method. Alat penggumpulan data yang digunakan yaitu kuesioner Brief Fatigue Inventory (BFI) dan Depression Anxiety Stress Scale (DASS). Peneliti melibatkan dua enumerator yang telah dilakukan persamaan persepsi dalam pengumpulan data. Data yang terkumpul diolah menggunakan SPSS, dan di analisis menggunakan uji Kruskal Wallis. Hasil penelitian menunjukkan adanya hubungan yang signifikan antara depresi dengan fatigue (p < 0,05). Sebagian besar pasien melaporkan fatigue sedang yang diperburuk oleh depresi sedang, yang menunjukankan bahwa fatigue dipengaruhi oleh interaksi antara efek fisik radioterapi dan kondisi psikologis yang memengaruhi kualitas hidup. Kata Kunci: Depresi, Fatigue, Kanker, Radioterapi
Factors Associated with Fatigue in Patients Undergoing Radiotherapy: A Literature Review Putra, Gian Dwi; Nelwati, Nelwati; Rahman, Dally
Indonesian Journal of Global Health Research Vol 6 No S5 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6iS5.4702

Abstract

Fatigue is one of the most common and disturbing symptoms among cancer patients, affecting almost all individuals undergoing radiotherapy, which lasts for a long time and interferes with the quality of life in performing daily activities. There has been a lot of research on the causative factors of fatigue in cancer patients undergoing radiotherapy. However, there is still a lack of literature review that looks at what are the factors that cause fatigue in cancer patients in general who undergo radiotherapy. This study aims to review existing literature to screen for factors contributing to fatigue in breast cancer patients undergoing radiotherapy. This study is a systematic review using The Joanna Briggs Institute Guideline and Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Of the 220 articles found in PubMed, ScienceDirect, and JSTOR databases (years 2017-2022), 77 articles met the full-text access criteria. After rigorous selection, 7 articles were selected for analysis. These articles were reviewed using a quantitative analysis approach to identify demographic, clinical, treatment, and psychosocial factors associated with fatigue in cancer patients undergoing radiotherapy. The results showed that there are several factors that cause fatigue in cancer patients undergoing radiotherapy including demographic factors (age, occupation, education level), clinical factors (hemoglobin level, comorbidities, cancer stage), treatment factors (number of fractions, fraction dose), and psychosocial factors (insomnia, anxiety, and depression). Management of fatigue in cancer patients undergoing radiotherapy requires a comprehensive approach that considers demographic, clinical, treatment, and psychosocial factors that influence the patient's condition. Thus, effective interventions should include all these factors to improve patients' quality of life.
Co-Authors Dally Rahman Nelwati, Nelwati Putri, Hadeci Lovenda