Article Per Year (5 Year)
p-Index From 2020 - 2025
0.61
P-Index
This Author published in this journals
All Journal Indonesian Journal of Medicine Indonesian Basic and Experimental Health Sciences
Matea, Ari
Unknown Affiliation
Health Professions Medicine & Pharmacology Nursing Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
The Correlation between Allergic Diseases and Systemic Lupus Erythematosus Pratiwi, Dewi; Wediningsih, Yulyani; Matea, Ari; Nareswari, Kirana Pawitra; Aryani, Niken Dyah
Indonesian Journal of Medicine Vol. 7 No. 1 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: The prevalence of autoimmune diseases and major chronic allergic diseases such as allergic rhinitis, asthma, and atopic dermatitis are increasing in line with the occurrence of climate change. Allergy and systemic lupus erythematosus (SLE) are sometimes being linked since both are immune diseases involving gene-environment interactions. The purpose of this research is to investigate the correlation between allergic diseases and SLE.Method: This case-control study was performed on 39 SLE subjects from the Tittari Community and 39 non-SLE subjects aged 15-49 years old, from September until October 2021. All of them were females. The independent variable was allergic disease and the dependent variable was SLE. Partici­pants' characteristics and allergy data were collected through answering the online Score for Allergic Rhinitis (SFAR) questionnaire, then the results were processed with bivariate and multivariate analyses.Results: The correlation between allergic diseases and SLE was significant for atopic dermatitis but not for allergic rhinitis and asthma (p=0.018; p=0.352; p=0.151 respectively). The bivariate analysis revealed that the risk of SLE was 3.17 times higher in atopic dermatitis patients (OR=3.17; 95% CI=1.20-8.39; p=0.018). Furthermore, the multivariate analysis found that subjects with atopic dermatitis had the highest risk of SLE (OR= 3.18; 95% CI= 1.07-9.51; p=0.031).Conclusion: Among allergic diseases, atopic dermatitis was found to be significantly correlated with SLE, where the risk of SLE was raised as the number of atopic dermatitis increased.Keywords: systemic lupus erythematosus, allergic diseases, allergic rhinitis, asthma, atopic dermatitisCorrespondence: Dewi Pratiwi. Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine, Universitas Sebelas Maret – Moewardi Hospital, Indonesia. Email: pratiwidewi81@staff.uns.ac.id. Phone: (0271) 664569.Indonesian Journal of Medicine (2022), 07(01): 19-27https://doi.org/10.26911/theijmed.2022.07.01.03
The Effect Of Administration Of Mecobalamin & Curcumin As Antioxidants In Nasopharynx Carcinoma Patients Post Cisplatin Regimen Chemotherapy With Hearing Impairment Matea, Ari; Primadewi, Novi
Indonesian Basic and Experimental Health Sciences Vol. 13 No. 1 (2024): November
Publisher : Rumah Sakit Umum Daerah Dr. Moewardi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/ibehs.vol13iss1pp1-6

Abstract

INTRODUCTION Nasopharyngeal carcinoma (NPC) is a common type of cancer in Southeast Asia, and its treatment often involves a cisplatin chemotherapy regimen. Ototoxicity is a side effect that often occurs in patients receiving this regimen. Antioxidant therapy, both synthetic and natural, such as curcumin, has been studied as having the potential to reduce ototoxicity due to cisplatin. This study was conducted to evaluate the effect of administering mecobalamin and curcumin as antioxidants in patients with nasopharyngeal carcinoma after cisplatin chemotherapy regimen with hearing loss. METHOD This study was an observational study with a cross sectional design, using consecutive sampling with inclusion criteria, namely patients diagnosed with NPC receiving the cisplastin regimen and willing to take part in the study. The data obtained was then analyzed using the Rank-Biserial Correlation's Test. Research approval was obtained from the Medical Research Ethics Commission, Faculty of Medicine, Sebelas Maret University/RSUD Dr. Moewardi Surakarta. RESULTS Of the 30 NPC patients who received cisplatin from the ENT-KL installation section of Dr Moewardi Hospital in the period March - September 2023, 30 data were obtained for each right ear and left ear. The average hearing threshold before intervention was 33.79 ± 10.40 dB and 34.10 ± 9.75 for the right and left ears. There was a difference in the average increase in hearing threshold for all parameters (Group I: Mecobalamin, Group II: Curcumin, Group III: Curcumin + Mecobalamin), with a value of p=0.000 (p<0.05). From these data it was concluded that the combined therapy of both was able to increase the hearing threshold along with the chemotherapy series. CONCLUSION Based on the research results, administration of mecobalamin and curcumin as antioxidants has a significant effect on patients with nasopharyngeal carcinoma after cisplatin chemotherapy regimen with hearing loss.
Co-Authors Aryani, Niken Dyah Dewi Pratiwi Nareswari, Kirana Pawitra Novi primadewi Wediningsih, Yulyani