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Meta-Analysis the Effect of Chlorhexidine and Povidone Iodine Mouthwashes on Viral Load SARS-CoV-2-Saliva Narulita, Danti; Rahardjo, Setyo Sri; Murti, Bhisma
Indonesian Journal of Medicine Vol. 7 No. 4 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2022.7.4.589

Abstract

Background: The strategy to reduce the risk of transmission of COVID-19 is to reduce the salivary SARS-CoV-2 viral load. Chlorhexidine and povidone iodine mouthwash are common active ingredients in oral antiseptics that have efficient viral activity against salivary SARS-CoV-2. This study aims to combine the results of several effect sizes regarding the effect of using chlorhexidine and povidone iodine mouthwash on the salivary SARS-CoV-2 viral load from various countries.Subject and Method: This study is a meta-analysis with the following PICO model, P: COVID-19 patients. I: use of chlorhexidine and povidone iodine mouthwash. C: no mouthwash. O: salivary SARS-CoV-2 viral load. A search for the articles used in this study was carried out using the keywords “COVID-19” OR “SARS-CoV-2” OR “viral load” OR “SARS-Cov-2 viral load” OR “Chlorhexidine mouthrinse” OR “Povidone Iodine mouthrinse ” OR “Randomized Controlled Trial” OR “RCT” between 2012-2022 from the PubMed, Springerlink, Elsevier, Google Scholar and Wiley Online Library databases. The inclusion criteria used in this study were full-text articles using a Randomized Controlled Trial (RCT) design. The analysis used was multivariate with Standardized Mean Difference (SMD). The articles collected were then critically reviewed using the PRISMA checklist, then the data were analyzed using the Review Manager 5.4 tool.Results: This meta-analysis examined 10 articles with a Randomized Controlled Trial (RCT) study design originating from Singapore, Saudi Arabia, Iran, Brazil, Italy, South Korea and Malaysia. A meta-analysis of 7 articles showed that the use of chlorhexidine mouthwash could reduce salivary SARS-CoV-2 viral load by 0.12 units lower than without the use of mouthwash (SMD= -0.12; 95% CI= -0.33 to 0.09; p=0.250). Meanwhile, 7 articles showed that the use of povidone iodine mouthwash could reduce the salivary SARS-CoV-2 viral load by 0.64 units lower than without the use of mouthwash (SMD= -0.64; 95% CI= -1.51 to 0.23; p=0.150).Conclusion: The use of chlorhexidine and povidone iodine mouthwashes can reduce the amount of salivary SARS-CoV-2 viral Keywords: mouthwash, chlorhexidine, povidone iodine, COVID-19, salivary SARS-CoV-2 viral load.Correspondence: Danti Narulita. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Jawa Tengah. Email: dantinarulita@yahoo.co.id. Mobile: +6282158818400.Indonesian Journal of Medicine (2022), 07(04): 387-400https://doi.org/10.26911/theijmed.2022.07.04.04
Meta-Analysis Study: Is Dental Health Education Effective to Improve Knowledge, Attitude, and Behavior in Adolescents? Narulita, Danti; Aprilianto, Danu
Journal of Health Promotion and Behavior Vol. 7 No. 3 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Good oral and dental health can help a person chew, talk and socialize with confidence without any discomfort. Teenagers are the next generation of the nation starting from the age of about 12 years to 20 years. At the age of adolescence, deciduous teeth have been replaced by permanent teeth so it is necessary to pay attention to the maintenance of teeth and mouth. This study aimed to analyze the effect of Dental Health Education (DHE) on the knowledge, attitudes and behavior of adolescents.Subjects and Method: This research is a meta-analysis study using PRISMA flowchart guidelines. The search for articles was carried out by considering the eligibility criteria determined using the following PICO model: Population= teenagers, Intervention= DHE (dental health education), Comparison= without DHE, Outcome= Knowledge, attitudes and behavior The article search process was carried out between 2020-2021 using a database from PubMed, Google Scholar, Mendeley and the Wiley Online Library. Based on the database, there were 7 articles that met the inclusion criteria. The analysis was carried out using RevMan 5.3 software.Results: A total of 7 articles reviewed in the meta-analysis showed that Dental Health Education (DHE) increased knowledge (SMD= 0.63; 95% CI= 0.53 to 0.73; p<0.001), attitudes (SMD= 0.41; 95% CI= 0.32 to 0.51; p<0.001) and behavior (SMD= 0.21; 95% CI= 0.11 to 0.32; p<0.001) adolescent.Conclusion: The influence of dental health education increase knowledge, attitudes and behavior among adolescents.Keywords: knowledge, attitude, practice, adolescent, dental health educationCorrespondence:Danti Narulita. Health Polytechnics, Ministry of Health Surakarta. Jl. Letjen Sutoyo, Mojosongo, Jebres, Surakarta, Central Java 57127. Email: danukalih@icloud.com. Mobile: +62821-3329-5468.Journal of Health Promotion and Behavior (2022), 07(03): 197-207DOI: https://doi.org/10.26911/thejhpb.2022.07.03.03
Pengaruh Sistem Jaminan Kesehatan Nasional (Jkn) Terhadap Pelayanan Konservasi Gigi Di Fktp Kota Surakarta Widyastuti, Noor Hafida; Narulita, Danti
Prosiding University Research Colloquium Proceeding of The 15th University Research Colloquium 2022: Bidang MIPA dan Kesehatan
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

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Abstract

Background of this study was National Health Insurance started on 1st January 2014. Dentist in Primary Health Care as a provider in primary case, these are promotive, preventive, curative and rehabilitative. This principle as a focus service in national Health Insurance System as gatekeeper. These concepts are credentialing and re-credentialing, four function of primary care these are first contact, continuity, comprehensive, coordination, competit ion and quality and cost control. Aim of this study to determine the impact of National Health Insurance system toward conservative dentistry treatment in Primary Health Care in Surakarta. Methods of this study was observational analytic with cross sectional study. The research subject were dentist who work in Primary Health Care in Surakarta. This research performed at Primary Health Care at Surakarta on February 2019. Instrument of this study were questionnare of National Health Insurance system and conservative dentistry treatment. Result of this study was majority of respondent (92%) have an optimal categorical applying National Health Insurance system and respondent (42%) have a good categorical giving a conservative dentistry treatment. Based on statistical test that has been done there is significant impact on both variables with p<0,05. Conclusion was there is an impact beetween National Health Insurance system and conservative dentistry treatment in Primary Health Care in Surakarta