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Meta-Analysis: Effect of Probiotics on the Frequency and Duration of Diarrhea in Children Under Five Ciptaningtyas, Wahyu Agustin Dwi; Murti, Bhisma; Rahardjo, Setyo Sri
Indonesian Journal of Medicine Vol. 5 No. 4 (2020)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (31.039 KB) | DOI: 10.26911/theijmed.2020.5.4.352

Abstract

Background: Digestive tract disease is still a health problem around the world, currently there are 2,544,084 cases of diarrhea in Indonesia in 2016. In the Central Java region, there are an estimated of 911,901 cases of diarrhea, while 95,635 cases of diarrhea have been handled. This study aims to estimate the magnitude of the effect of probiotics on the frequency and duration of diarrhea among toddler based on the results of a number of similar previous studies.Subjects and Method: This study was a systematic study and meta-analysis, with PICO as follows: Population= children under five. Intervention= Probiotics. Comparison= Not Probiotic. Outcome= Frequency and Duration of Diarrhea in toddlers. The articles used in this study were obtained from several databases including PubMed, Springer Link, Cochrane Database, Hindawi, Elsevier, JBBA, LWW, Google Scholar. The keywords for search­ing articles are as follows: "Probiotic", OR "fre­quency", OR "diarrhea", "kid", OR child "AND" Randomized Controlled Trial (RCT). The articles included in this study were full text articles with a randomized controlled trial study design. Articles were collected using PRISMA flow diagrams. Articles were analyzed using the Review Manager 5.3 application.Results: A total of 12 articles reviewed in this meta-analysis study originated from India, Canada, Indonesia, America, Iran. Studies showed that the effect of probiotics decreased the frequency (Standarized mean difference -0.32; 95% CI= -0.67 to 0.03 p= 0.070). The effect of probiotics reduced the duration of diarrhea in children under five (Standarized mean diffe­rence= -0.74; 95% CI= -1.60 to 0.12 p= 0.090).Conclusion: Probiotics reduced the frequency and duration of diarrhea in toddlers.Keywords: Probiotics, Frequency, Diarrhea, ToddlersCorrespondence: Wahyu Agustin Dwi Ciptaningtyas. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126,  Central Java. Email: agustinfaa@gmail.com.Indonesian Journal of Medicine (2020), 05(04): 321-330https://doi.org/10.26911/theijmed.2020.05.04.07. 
Meta-Analysis: The Effect of Diabetes Mellitus Comorbidity on the Risk of Death in Covid-19 Patients Kun'ain, Utin Ilma Agni; Rahardjo, Setyo Sri; Tamtomo, Didik Gunawan
Indonesian Journal of Medicine Vol. 5 No. 4 (2020)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (30.841 KB) | DOI: 10.26911/theijmed.2020.5.4.357

Abstract

Background: Corona Virus Deases 2019 (COVID-19) is an infectious disease caused by the corona virus. COVID-19 is currently a challenge for diabetes patients. Diabetes mellit­us predisposes to a very severe disease course and increases the risk of death from COVID-19. This study aims to estimate the average mag­ni­tude of the effect of diabetes mellitus comor­bi­dity on the risk of death of COVID-19 patients.Subjects and Method: This was a systematic review and meta-analysis. This research was conducted using secondary data that will be conducted by searching and selecting data from the results of clinical trials conducted around the world. Search for articles through syste­matic and comprehensive databases from Pub­med, Google Scholar, Springer Link. The ana­lysis in this study was carried out using the Review Manager 5.3 software. The results of the analysis are the effect size, heterogeneity and then the study model. Variations between studies are used to determine the analysis model which is divided into two models, namely the fixed effect model (FEM) and the random effect model (REM).Results: Based on the results of the analysis, there was high heterogeneity between experi­ments (I2= 85%; p= 0.04), so that the Random Effects Model (REM) was used. COVID-19 patients with comorbid diabetes mellitus were 2.17 times more likely to die than patients without comorbid diabetes mellitus (aOR 2.17; 95% CI 1.04 to 4.54).Conclusion: Diabetes mellitus co-morbidity increases 2.17 times the risk of death in COVID-19 patients compared to patients without dia­betes mellitus comorbidity.Keywords: COVID-19, Comorbidity, Diabetes Mellitus, DeathCorrespondence: Utin Ilma Agni Kun'ain. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36 A, Surakarta 57126, Central Java. Email: utinilmaagni8p@gmail.com. Mobile: +628111044542.Indonesian Journal of Medicine (2020), 05(04): 368-377https://doi.org/10.26911/theijmed.2020.05.04.12. 
Meta-Analysis of Risk Factors for Lower Extremity Amputation in Diabetes Mellitus Patients with Foot Ulcers Septiani, Anissa Eka; Rahardjo, Setyo Sri; Prasetya, Hanung
Indonesian Journal of Medicine Vol. 5 No. 4 (2020)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (31.044 KB) | DOI: 10.26911/theijmed.2020.5.4.355

Abstract

Background: Diabetic foot ulcer is a compli­cation of diabetes mellitus which costs high, takes long wound care, increases mortality, morbidity and causes non-traumatic amputa­tion. There are risk factors that are thought to be the cause of lower limb amputation in diabetic foot ulcers, namely peripheral artery disease, hypertension and gender. This study aims to estimate the influence of peripheral artery disease, hypertension and gender on the risk of lower limb amputation in diabetes mellitus patients with leg ulcers.Subjects and Method: Meta-analysis studies and systematic reviews were applied to this study using electronic databases of Pubmed, Scopus, Google Scholar, and Springer Link. The keywords to search for articles are as follows: "diabetic foot", "lower limb amputation", "low­er extremity amputation", "risk factor", "predic­tor", "cohort", "retrospective", "adjusted odds ratio". Articles were collected using PRISMA diagrams, and analyzed using the Review Manager 5.3 application.Results: Meta-analysis of 9 cohort articles of diabetic foot ulcer patients with peripheral artery disease (aOR= 2.46; 95% CI= 1.70 - 3.55; p<0.01); Meta-analysis of 8 cohort articles, diabetic foot ulcer patients with hypertension (aOR= 1.05; 95% CI= 0.66 - 1.68; p= 0.83); Meta-analysis of 9 cohort articles of male diabetic foot ulcer patients (aOR= 1.60; 95% CI= 1.32 - 1.94; p<0.01); Peripheral artery disease, hypertension and male gender are risk factors that can increase the incidence of lower limb amputation.Conclusion: Peripheral artery disease, hypertension and male gender are risk factors that can increase the incidence of lower limb amputation.Keywords: Peripheral artery disease, diabetic foot ulcer, lower limb amputationCorrespondence: Anissa Eka Septiani. Masters Program in Public Health. Universitas Sebelas Maret. Jl. Ir. Suta­mi 36A, Surakarta 57126, Central Java,. Email: sanissaeka@gmail.com. Mobile: 08951­464­6458.Indonesian Journal of Medicine (2020), 05(04): 343-355https://doi.org/10.26911/theijmed.2020.05.04.10. 
Meta-Analysis: The Effect of Malaria Infection on the Incidence of Low Birth Weight Anggara, Feri Yuda; Rahardjo, Setyo Sri; Murti, Bhisma
Journal of Maternal and Child Health Vol. 5 No. 5 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Malaria is a parasitic infectious disease. Malaria contributes to morbidity and mortality in high-risk groups, namely pregnant women and children under five. Malaria infec
Contextual Effect of Posyandu on the Risk of Stunting in Children Under Five, Klaten, Central Java Mariyana, Anna; Dewi, Yulia Lanti Retno; Rahardjo, Setyo Sri
Journal of Maternal and Child Health Vol. 5 No. 6 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Stunting is a condition of failure to thrive in children under five as a result of chronic malnutrition. Environmental inter
Contextual Effect of the Integrated Health Post and Social Capital on Completeness of Child Immunization in Pacitan, East Java Prabowo, Puspita Mayangsari; Rahardjo, Setyo Sri; Pamungkasari, Eti Poncorini
Journal of Maternal and Child Health Vol. 5 No. 5 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Background: Around 2-3 million deaths each yearwere caused by diseases that could be pre
Effects of Peer-Based Intervention on Prevention Behavior of Sexually Transmitted Infections and Unwanted Pregnancy in Adolescents: A Meta Analysis Safitri, Denanda Agnes; Rahardjo, Setyo Sri; Murti, Bhisma
Journal of Maternal and Child Health Vol. 5 No. 6 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Background:In facing the transition peri
Multilevel Analysis of Dengue Hemorrhagic Fever in Bantul Regency Nurkhairani, Nurkhairani; Rahardjo, Setyo Sri; Murti, Bhisma
Journal of Maternal and Child Health Vol. 6 No. 2 (2021)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Dengue Hemorrhagic Fever (DHF) is one of the main vector-borne diseases infecting humans. It remains a major public health problem in tropical and sub-tropical regions around the world. The poor physical and social environment are the leading cause of the increasing incidence of DHF. This study aimed to determine the effect of the physical and social environment on dengue incidence using multilevel analysis.Subjects and Method: This was an analytic a case-control study conducted in Bantul, Yogya
Meta-Analysis the Effect of Oral and Injection Contraceptives on Breast Cancer Dilma’aarij, Dilma’aarij; Rahardjo, Setyo Sri; Pamungkasari, Eti Poncorini
Journal of Maternal and Child Health Vol. 6 No. 2 (2021)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Background: Oral contraceptives and injec
Meta-Analysis the Effect of Complementary Feeding Practice on Stunting in Children Aged 6-59 Months Babys, Isna Yuswella; Dewi, Yulia Lanti Retno; Rahardjo, Setyo Sri
Journal of Maternal and Child Health Vol. 7 No. 4 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (34.567 KB) | DOI: 10.26911/thejmch.2022.07.04.10

Abstract

Background: A child's ability to achieve growth standards is determined by the adequacy of food intake. Malnutrition in toddlers increases the risk of stunting, which is a serious problem. Stunting is closely related to neurocognitive development, risk of non-communicable diseases, and decreased productivity. Appropriate complementary feeding is an important milestone in efforts to improve survival and promote healthier child growth and development and can significantly reduce stunting. This study aims to estimate the magnitude of the effect of poor complementary feeding practices on the incidence of stunting in toddlers using a meta-analysis study. Subjects and Method: The meta-analysis was carried out with the initial step of formulating the research problem using the PICO technique. The study population were children aged 6-59 months with poor complementary feeding, compare with good complementary feeding. The study outcome was stunting. Articles were selected from Google Scholar, PubMed, Springer Link, and Research Gate databases. The keywords used were "complementary Feeding practice" OR "meal frequency" OR "dietary diversity" AND "Stunting". The inclusion criteria were full text, observational studies, and the results reported in Adjusted Odds Ratio (aOR). Analysis of articles using RevMan 5.3. Results: A meta-analysis involved 16 articles. The results showed that the low variety of complemen­tary feeding increased the incidence of stunting 1.72 times compared to various types of complementary feeding (Aor= 1.72; 95% CI= 1.54 to 1.92; p < 0.001). Infrequent complementary feeding increased the incidence of stunting by 1.85 (aOR= 1.85; 95% CI 1.34 to 2.55; p <0.001). Conclusion: The diversity of types of complementary foods and low frequency of giving complementary foods increase the incidence of stunting in children aged 6-59 months. Keywords: complementary feeding practice, feeding frequency, food diversity, stunting. Correspondence: Isna Yuswella Babys. Master’s Program in Public Health Sciences, Universitas Sebelas Maret, Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: isnababys@gmail.com. Mobile: 082354707563.
Co-Authors Abda Abda Adi Magna Patriadi Nuhriawangsa Afifah Noer Agus Kristiyanto Akbar, Muh. Syaiful Ambarsari, Anggraini Anggara, Feri Yuda Anggriani, Atika Febri Arlina Azka Arum Nuryati Atika Mima Amalin Babys, Isna Yuswella Bachtiar, Erlangga Yusa Bhisma Murti Budinugroho, Agustaria Chasanah, Eka Siti Ciptaningtyas, Wahyu Agustin Dwi Daniyar, Pamogsa Ratri Adha Devi, Rhisma Mutiara Dewi, Patria Sari Didik Gunawan Tamtomo Dilafa, Rynda Arum Dilma’aarij, Dilma’aarij Dono Indarto Endang Sutisna Sulaeman Eti Poncorini Pamungkasari Fadhilah, Azzahra Nur Fatati, Muhibbah Firdausi Nuzula FIRDAUSI NUZULA Fitriyani, Ayu Laela Habibi, Mustainu Hapsari, Faricha Indra Hidayati, Khairina Nur Ichsan, Burhannuddin Ida Nurwati Inayati, Rizqi Indana, Alifiya Zulfa Irfandi, Julhan Karmany, Putu Anggi Widia Khoirunnisa' Maftuch, Atiqoh Kumala, Yovita Eka Ratna Kun'ain, Utin Ilma Agni Kurniagung, Philipus Prihantiko Lilik Wijayanti Mariyana, Anna Maya Ayu Riestiyowati MIFTAKHUL JANNAH Mujiran, Mujiran Narulita, Danti Noor Alis Setiyadi Novika, Revi Gama Hata Novika, Revi Gama Hatta Nurhayati, Farida Nuriza, Rizky Alfiqi Nurkhairani, Nurkhairani Nuswantari, Atika Pambudi, Gigih Cita Pardosi, Firman Pawito Pawito Prabowo, Puspita Mayangsari Praptiwi, Juni Prasetya, Hanung Pratama, Genn Andrean Purwaningtyas, Niniek Rahmawati, Rahmawati Ratih Puspita Febrinasari Ratna Kusumawati Retyono, Sugeng Rita Adriani Benya Adriani ROHMAH, LAILATUL Rr. Vita Nurlatif Safitri, Denanda Agnes Saputra, Rizki Kurniawan Sari, Niken Kartika Sari, Victoria Husadani Permata Septiani, Anissa Eka Sinu Andhi Jusup, Sinu Andhi Sri Wulandari Sukamto, Ika Sumiyarsi Sukandriani Utami Sulastomo, Heru Sulistyani, Retno Sumardiyono Sumardiyono Sunarto, S Suselo, Yuliana Heri Syafira, Muthia Tari, Putri Inrian Tri Nugraha Susilawati Tri Yonita, Maria Regina Vitri Widyaningsih Wicaksono, Satriyo Fajar Widiantoro, Reza Wijaya, Veronica Fenny yulia lanti retno dewi Yumafita, Tiara Yusuf Ryadi Zahra, Fathia Mutiara