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All Journal Smart Medical Journal Jurnal Info Kesehatan
Agung Prabowo, Nurhasan
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Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Difference of Cycle Threshold Value, Oxygen Saturation and D-dimer to COVID-19 Vaccination Redhono Harioputro, Dhani; Dasa Ramadhan, Arsyi; Nurhayatun, Evi; Budi Susilo, Satrio; Agung Prabowo, Nurhasan
JURNAL INFO KESEHATAN Vol 21 No 2 (2023): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol21.Iss2.1204

Abstract

Many factors can affect the prognosis of COVID-19 patients, and Cycle Threshold value can be used to estimate the amount of virus in the body. Oxygen saturation and D-dimer are important components in determining the severity. This study aims to analyze the difference of CT value, oxygen saturation, D-dimer, and degree of severity on vaccination state. This study is the observational analytic study of patients admitted to the isolation ward of a referral hospital in Surakarta, Indonesia. The analysis covered assessing the normality of the data, the Kruskal-Wallis correlation test, and ANOVA to assess the differences between variables. A total of 154 patients with, 65.6% of them did not participate in the full vaccination program. The results of the analysis showed a significant difference between the D-dimer and the degree of severity with a p-value of < 0.05, while the CT value and oxygen saturation had no significant difference with the vaccination state. Vaccination showed a significant difference with D-dimer and the degree of severity of COVID-19 infection, so giving a complete vaccine can reduce the severity of COVID-19 patients, and we recommended to be able to complete the vaccine for the whole community.
A 21-Year-Old Woman with Suspecting Gitelman Syndrome Denny, Berty; Agung Prabowo, Nurhasan; Puspa Putri, Desy; Myrtha, Risalina; Apriningsih, Hendrastutik
Smart Medical Journal Vol 5, No 2 (2022): Smart Medical Journal
Publisher : Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/smj.v5i2.61735

Abstract

Introduction: Gitelman syndrome (GS), is a hereditary condition marked by a specific kidney function impairment. GS symptoms do not normally manifest until beyond the age of six years. We present a rare case of a 21-year-old woman with a background in generalized weakness muscle cramps with tetany, fever, and dyspnea.  The goal of this study is to give a case report of Gitelman syndrome suspicion.Result: Gitelman syndrome is identified through clinical indicators and lab testing, such as low potassium and magnesium levels in the blood, metabolic alkalosis, and low calcium levels in the urine. We do a variety of physical and laboratory tests to determine the disease and rule out other possibilities. Molecular proof is difficult to get due to a lack of resources and the high expense of genetic testing, which has become one of our case report's flaws. This patient was diagnosed as suspecting Gitelman syndrome and treated for electrolyte imbalances. The patients were given replacement therapy, which comprised intravenous potassium, sodium, and chloride therapy, as well as calcium therapy. In addition, we also provided some symptomatic therapy. She was discharged five days later in fine condition.Conclusion : This is one of the few reports of a 21-year-old lady being suspected of having Gitelman syndrome (GS). We conduct a battery of physical and laboratory tests to diagnose the disease and rule out other possibilities. We provide the appropriate therapies in accordance with the guidelines, and the outcomes are favorable.
Co-Authors Apriningsih, Hendrastutik Budi Susilo, Satrio Dasa Ramadhan, Arsyi Denny, Berty Myrtha, Risalina Nurhayatun, Evi Puspa Putri, Desy Redhono Harioputro, Dhani